Gene Information

Name : Dbac_1915 (Dbac_1915)
Accession : YP_003158421.1
Strain : Desulfomicrobium baculatum DSM 4028
Genome accession: NC_013173
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 2203843 - 2207013 bp
Length : 3171 bp
Strand : -
Note : PFAM: acriflavin resistance protein; KEGG: sus:Acid_5798 acriflavin resistance protein

DNA sequence :
ATGAATATCGCGGAGTGGAGCATACGCAAGAGCGTCATCAGCTGGGTCATGACCATCCTTTTTCTGGTGGTCGGATGGTA
CTCCTTCAATAATCTGAGCAGGCTGGAAGACCCGGAGTTCACCATCAAGGAGGCGGTCATCATCACCCCGTATGCGGGGG
CCTCGGCGGAGCAGGTGGAGGAAGAGGTCACCAACGTGATCGAGAAGGCCTGCCAGGAGATGGGCCAATTGGAGCGGGTG
GAGTCGAGATCCTCGCGGGACTTGTCCATCGTGCAGGTCACGATGAAGGACAACTTTGACAAGTCCTCCTTGCCTCAGGT
CTGGGACGAGCTGCGGCGCAAGGTTTCCGACGCGCAGCGCAGTCTGCCGCCCGGCGCCGGGCCATCCATCGTCAATGACG
ATTTTGGCGATGTTTACGGCGTCTTTCTGGCCATCACCGGAGAGGGCTATACGCCGCGCGAACTTCACGAGTACGCCAAG
TTTCTGCAGCGCGAGCTCTTGAAGGCCAAGGACGTGAAGCGGATCATGCTTTACGGCGTGCAGAAGGAGGCCATCTTCAT
CGAGATGCGCCGCGAAAAAATGTCCCAATTCGGCGTTGCTCCGTCCGATATCGCAGGCGCCCTGAAGGCCAAGAACATTC
CGGCCAGCGGTGGGCATCTGCCGCTGGGGGGCGAATACATCCCCATCAGCCCCACGGGCGAATTCAAATCCGAGCAGGAC
ATCGGCGGGCTGCTCATCAAGGGCATGGGGTCGGACAGCACGGTCTATCTGCGTGACGTGGCCGACATCAAGCGCGACTA
CATCGCTCCGCCGGATGCGATCCTGCGTTACGACGGCAAGCCCGCCATCGGGCTGGCCGTGTCCACCGTTCTGGGCGGCA
ACGTGGTCGACATGGGCGAGTCTCTGGATCAGCGTTTCCGCGAGCTTGAATCCATGCGTCCGGTGGGCATGGAGCTGCAC
GTCATCTCGCACCAGAGCCGGGCCGTGACCGAGGCCATCAACGGTTTTCTGATCAACCTGCTGGAGGCCGTGGCCATCGT
CGTGGTGGTGCTGCTCATATTCATGGGGCTGCGCAGCGGGCTGATCATCGGGGCGGTCCTTGTGATCACCATCATGGCGA
CTTTTATCGTCATGGACCTGGGCGACATCACTCTGGAGAGGATCTCGCTCGGCGCGCTGGTCATCGCGCTGGGCATGCTG
GTCGACAATGCCATCGTGGTCACGGACGGGATGAAGGAGAAGATGAACCGGGGCGTCGACGCTCTGACCGCTGCCCGTGA
TGTCGTGGGACAGGTCGGGGTGCCGCTCCTGGGCGCGACCTTCGTGGCCGTGGCCGCCTTTGCCGCCATCGGCACTTCCC
AGGACAGCACGGGAGAATATTGCCGTTCCCTCTTTTATGTCATTCTCATTTCCCTGCTCATGAGCTGGGTCACGGCCGTG
AACACCACCCCGCTCTTTTGCAAGACGTTTCTGAAGGTCAGGCCGCAAAACGCGGACGGCTCAAGCGCCTCCCCCGATCC
TTATGGCGGGAGATTCTACTGCGCATATCGCGTCTTTCTGGCGTGGTGCATCCGCTGGCGCTGGGTCACTGTGGCGGTCG
TGGTCGCCCTGTTCATCGCGTCCATGGTCGGCTTTGGAACCCTCAAGAACAGCTTCTTCCCGGACTCGACCAGAGCACAG
TTCTACGTGGACTTCTGGTTCGCCGAGGGCACTGACATCCGCGAAACCCAGCGGCAACTGGAGCGGGCCGAAGCGGATAT
CGGCAGGCGCGAAGGCGTGACCCACATGACGACCATGATCGGGGGAGGGCAGGTCCGTTTCCTGCTGACCTATCCGACGG
AGAAGAGTTACGACGCCTTTGGCCAGATCCTTGTCGACGTTGACGATTACAAGCGCATCCCGGGCCTGACCAAGGAGATT
CAGCGGGATCTCGACCGCTTGTTCCCTGAGGCTCTGGTCAGCGTGCGGCTCTTTGTGCTTGGACCCTCCGTGGGCGGCAA
GCTCCAGCTGCGGCTGTACGGTCCCGATTCGACGGTCCTCAGGGAACTCGCCGCCAAGGCGGAGCAGGTGCTGCTGGATG
ACCCGCACGCCAAGTCCGTGCGCAACGAGTGGCGGCAGAAGGCCAAGGTCATGCGGCCCCGGATGGCCGAAGTTCCGGCG
CTCAAGGCCGGCATCGAGAGGCCGCAGATCGCCACGGCTTTCGAGTCTGTCTTCGAGGGTACCCGGGTGGGCGTGTTCAA
GGAGCGCGACGAACTGCTTCCGATCATCACGCGTGCTCCGGAAGAGGAGCGCGCCGACCTGGACAGCATGGAGGGCATGC
CCATCTGGAGTCCGGCCGCGCAATCCATGATTCCCATTGGTCAGGTGCTTTCCGGCATAACCATGGAGTTCGAGGACGCC
TATCTGTGGCGGCGGGATCGTTTCAAGATGCTGCGCATTCATGCCGATCCCAGCGAGGGCCTGCCGAGCGAGCTGATGCA
GCGCGTGAAGCCCAGGATCGAGCAGGTTCTGAACGTGGATGTGGCGCAGGTGCTCGGAAAAACCCTTCCGCCCGGAGAGG
ATCCCTTTCAAAAGGACTATGACGCCTCGACGCTCAAGGTCGGTTACTCAGACAAATGGCCCATAAAGGATATGCCCGGC
TACTACATGGCCTGGGGCGGTGAGTCCGAAGACTCGGCCAAGGCCAATGCGCGCCTCGCGGGCACCATCCCGGTGTTCTT
CGGCCTCATGGTGCTCATTGTCATCGTGCTCTTCAACTCCATCAAGAAGACCCTGGTCATCTGGCTTACCGTGCCCCTCT
CCGTCATCGGCGTGACCGCGGGCCTCTTGCTCTTCAACCAGCCTTTCGGGTTCATGTCCCTGCTTGGTCTCATGAGCCTC
TCGGGCATGCTCATCAAGAACGCCATCGTGCTGATCGATCAGATCGATGTGGAAACCGGGAGCGGCAAACCTCCCTTCAA
GGCAGTCCTCGATTCCGGCGTCAGTCGCCTCATTCCCGTGTCCATGGCCGCCCTGACCACGATTCTTGGCATGCTCCCCC
TGGTCCAGGATGCCTTCTTCGTGTCCATGGCGGTGACCATCATGTTCGGCCTCGGGTTCGCCACGGTCCTGACCCTGATT
GTCGTGCCGGTGCTCTATGCCATCTTTTTCAACGTGAAGTGCGAGGAATAG

Protein sequence :
MNIAEWSIRKSVISWVMTILFLVVGWYSFNNLSRLEDPEFTIKEAVIITPYAGASAEQVEEEVTNVIEKACQEMGQLERV
ESRSSRDLSIVQVTMKDNFDKSSLPQVWDELRRKVSDAQRSLPPGAGPSIVNDDFGDVYGVFLAITGEGYTPRELHEYAK
FLQRELLKAKDVKRIMLYGVQKEAIFIEMRREKMSQFGVAPSDIAGALKAKNIPASGGHLPLGGEYIPISPTGEFKSEQD
IGGLLIKGMGSDSTVYLRDVADIKRDYIAPPDAILRYDGKPAIGLAVSTVLGGNVVDMGESLDQRFRELESMRPVGMELH
VISHQSRAVTEAINGFLINLLEAVAIVVVVLLIFMGLRSGLIIGAVLVITIMATFIVMDLGDITLERISLGALVIALGML
VDNAIVVTDGMKEKMNRGVDALTAARDVVGQVGVPLLGATFVAVAAFAAIGTSQDSTGEYCRSLFYVILISLLMSWVTAV
NTTPLFCKTFLKVRPQNADGSSASPDPYGGRFYCAYRVFLAWCIRWRWVTVAVVVALFIASMVGFGTLKNSFFPDSTRAQ
FYVDFWFAEGTDIRETQRQLERAEADIGRREGVTHMTTMIGGGQVRFLLTYPTEKSYDAFGQILVDVDDYKRIPGLTKEI
QRDLDRLFPEALVSVRLFVLGPSVGGKLQLRLYGPDSTVLRELAAKAEQVLLDDPHAKSVRNEWRQKAKVMRPRMAEVPA
LKAGIERPQIATAFESVFEGTRVGVFKERDELLPIITRAPEEERADLDSMEGMPIWSPAAQSMIPIGQVLSGITMEFEDA
YLWRRDRFKMLRIHADPSEGLPSELMQRVKPRIEQVLNVDVAQVLGKTLPPGEDPFQKDYDASTLKVGYSDKWPIKDMPG
YYMAWGGESEDSAKANARLAGTIPVFFGLMVLIVIVLFNSIKKTLVIWLTVPLSVIGVTAGLLLFNQPFGFMSLLGLMSL
SGMLIKNAIVLIDQIDVETGSGKPPFKAVLDSGVSRLIPVSMAALTTILGMLPLVQDAFFVSMAVTIMFGLGFATVLTLI
VVPVLYAIFFNVKCEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 1e-180 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Dbac_1915 YP_003158421.1 acriflavin resistance protein BAC0428 Protein 0.0 47
Dbac_1915 YP_003158421.1 acriflavin resistance protein BAC0519 Protein 0.0 47
Dbac_1915 YP_003158421.1 acriflavin resistance protein BAC0526 Protein 5e-180 43
Dbac_1915 YP_003158421.1 acriflavin resistance protein BAC0425 Protein 0.0 42