Gene Information

Name : Bfae_08030 (Bfae_08030)
Accession : YP_003154247.1
Strain : Brachybacterium faecium DSM 4810
Genome accession: NC_013172
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase/cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 911865 - 912998 bp
Length : 1134 bp
Strand : +
Note : PFAM: Cys/Met metabolism PLP-dependent enzyme

DNA sequence : 
GTGCACATCCAGACCGCCGCCGTGCATACCCTGAGGGACTTCGAGCACGGGGCGGTGGTCCCGCCCGTCCACCTCGCCTC
GACCTTCGAGCTCGACCCCGCCACCGAGGACGGCGCCTACGCGTACCAGCGCGGCTCCAACCCGACCCGTGCGCAGCTCG
AGACGGTGCTGGCCGCGCTCGACGATGCGGAGCACGGCTTCGCCTTCGCCTCCGGCATGGCCGCGACCGCCGCCGCGCTG
TCCACCCTCACGGTCGGTGACGAGGTGCTGCTGCCGGCCAGCGTCTACGGCGGGACCTACCGCTTCGTGGACCTCGTCCT
GCCCGGCCGCGGGATCACCGGGCGCTTCGTGGACGACCTCGGGGCGCTCACGGACGCGGACTTCACGCCCAGCACCCGGG
CGGTCTTCATCGAGACGCCGGCCAACCCGACCCTGCGGATCACGGACCTGCGCCGCATCATCGAGCTCGCGCACCGCCAC
GGCGCGCTGGTGATCGTCGACAACACCTTCATGACCCCGGTGCTGCAGAAGCCCCTCGCGCTCGGCGCGGACATCGTCGT
GCAGTCCGCCACGAAGTACCTCGCCGGGCACTCCGACCTGCTCGCGGGCACCGTCACCACGAACGACGACACGCTCGCCG
AGGCCTTCGCCCTCGCCCAGAAGGCGCAGGGCGGCGTGCTCGCCCCGCAGGACTCCTTCCGCCTGATCCAGGCGATCAAG
ACCCTCCCGCTCCGGCTCGAGCGCCAGCAGTCCAACGCGGAGGCGATCGTCGCGCACCTGCGCGAGCACGAGGGCATCCG
GCAGGTGTGGTACCCCGGCTCGCACAGCGAGGAGGAGGCGCGCATCCACGCCTCGCAGGCCAGCGGAAACGGGGCGGTGC
TCTCCTTCGAGCTCGCCGCCGGCCTCGACAGCGTCGCCTTCCTGCGGGCGCTGCGGTTCCCGGCCTACGCCGTGAGCCTC
GGCGGCGTCGAGTCGCTGATCTGCCGCCCCGCCACCATGACGCACGAGGCGATGACCCCCGAGGCCCGGCAGAACGCGGG
CATCTCCGACGAGCTGCTGCGCCTGAGCGTCGGCATCGAGGACGTCGCGGATCTCCTCGCCGACCTGGACCAGGCGCTCG
CCGCCGCCCGCTGA

Protein sequence : 
MHIQTAAVHTLRDFEHGAVVPPVHLASTFELDPATEDGAYAYQRGSNPTRAQLETVLAALDDAEHGFAFASGMAATAAAL
STLTVGDEVLLPASVYGGTYRFVDLVLPGRGITGRFVDDLGALTDADFTPSTRAVFIETPANPTLRITDLRRIIELAHRH
GALVIVDNTFMTPVLQKPLALGADIVVQSATKYLAGHSDLLAGTVTTNDDTLAEAFALAQKAQGGVLAPQDSFRLIQAIK
TLPLRLERQQSNAEAIVAHLREHEGIRQVWYPGSHSEEEARIHASQASGNGAVLSFELAAGLDSVAFLRALRFPAYAVSL
GGVESLICRPATMTHEAMTPEARQNAGISDELLRLSVGIEDVADLLADLDQALAAAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-61 45
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-60 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 9e-53 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bfae_08030 YP_003154247.1 cystathionine beta-lyase/cystathionine gamma-synthase BAC0207 Protein 4e-47 43