Gene Information

Name : Bfae_28630 (Bfae_28630)
Accession : YP_003156217.1
Strain : Brachybacterium faecium DSM 4810
Genome accession: NC_013172
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 3223253 - 3224776 bp
Length : 1524 bp
Strand : +
Note : PFAM: Aldehyde dehydrogenase family

DNA sequence :
ATGAGCGTCTACGCACGCCCGGGCACCGACGGGGCGAAGGTCAGCTTCAAGGCCCGCTATGAGAACTACATCGGCGGTGG
TTGGGTCGCGCCCGTGAAGGGCGAGTACTTCGAGAACCCCACGCCCGTCACCGGCCAGGTGTTCACCGAGGTGGCGCGCT
CCACCGCGGAGGACATCGAGCTCGCGCTCGACGCCGCACACGCCGCCGCCCCCGCATGGGGGGCGACGTCGGTCGCCGAA
CGCGCGCTGATCCTGAACCGGATCGCCGACCGCATCGAGGAGAACCTCGAGATGCTGGCGGTGGCCGAGACGTGGGACAA
CGGCAAGCCGATCCGCGAGTGCCTGAACGCGGATCTGCCGCTGGCGGTGGACCATTTCCGGTACTTCGCCGGCGCGATCC
GGGCGCAGGAGGGTGCCCTGTCGCAGATCGACGACGACACCGTCGCCTATCACTTCCATGAGCCGCTCGGAGTGGTCGGC
CAGATCATCCCGTGGAACTTCCCGCTGCTCATGGCGACCTGGAAGCTGGCGCCCGCGCTCGCGGCCGGCAACGCCGTGGT
GCTCAAGCCCGCCGAGCAGACCCCGGCCTCGATCATGGTGCTCGCCGAGCTGATCGGCGATCTCCTGCCCGAGGGCGTGC
TGAACATCGTCAACGGCTTCGGCGCGGAGGCCGGCAAGCCGCTCGCCTCGAACAAGCGGATCCGGAAGATCGCCTTCACC
GGCGAGACCACCACCGGGCGTCTGATCATGCAGTACGCCTCGCAGAACCTGATCCCGGTCACCCTCGAGCTGGGCGGCAA
GAGCCCGAACATCTTCTTCGGCGACGTCGCCTCCGCCCAGGACGACTACTACGACAAGGCGCTCGAGGGCTTCGCGATGT
TCTCGCTGAACCAGGGCGAGGTGTGCACCTGTCCCTCGCGGGCGCTCGTGGAGTCCTCGATCTACGACTCCTTCGTGGCC
GACGGCATCGCCCGCGTGGAGGCCACGACGCAGGGCGACCCGCTGGACACCGACACGATGATCGGCGCGCAGGCCAGCAA
CGACCAGCTGGAGAAGATCCTCTCCTACCTCGACATCGGCACGCAGGAGGGCGCGAAGCTGCTCACCGGCGGCGAGCGCG
CCGATCTCGGCGGCGACCTCTCGGGCGGCTACTACGTCACCCCCACGATCTTCGAGGGCGACAACTCGATGCGGATCTTC
CAGGAGGAGATCTTCGGTCCGGTGCTCGCGCTGACGCGGTTCGACGGCTACGACGAGGCGATCTCGATCGCGAACGACAC
CCTGTACGGGCTGGGCGCCGGTGTGTGGTCGAGGCAGCAGAACACCGTCTACCGCGCCGGCCGCGCCATCCAGGCCGGTC
GCGTGTGGGTGAACCACTATCACAGCTACCCGGCGCACTCCGCGTTCGGCGGGTACAAGTCCTCGGGCATCGGTCGGGAG
AACCACCTGATGATGCTCGACCACTACCAGCAGACGAAGAACCTGCTGGTCAGCTACTCGGAGCAGAAGCTCGGCTTCTT
CTGA

Protein sequence :
MSVYARPGTDGAKVSFKARYENYIGGGWVAPVKGEYFENPTPVTGQVFTEVARSTAEDIELALDAAHAAAPAWGATSVAE
RALILNRIADRIEENLEMLAVAETWDNGKPIRECLNADLPLAVDHFRYFAGAIRAQEGALSQIDDDTVAYHFHEPLGVVG
QIIPWNFPLLMATWKLAPALAAGNAVVLKPAEQTPASIMVLAELIGDLLPEGVLNIVNGFGAEAGKPLASNKRIRKIAFT
GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFGDVASAQDDYYDKALEGFAMFSLNQGEVCTCPSRALVESSIYDSFVA
DGIARVEATTQGDPLDTDTMIGAQASNDQLEKILSYLDIGTQEGAKLLTGGERADLGGDLSGGYYVTPTIFEGDNSMRIF
QEEIFGPVLALTRFDGYDEAISIANDTLYGLGAGVWSRQQNTVYRAGRAIQAGRVWVNHYHSYPAHSAFGGYKSSGIGRE
NHLMMLDHYQQTKNLLVSYSEQKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-140 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-149 62
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-149 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-149 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-148 62
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bfae_28630 YP_003156217.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 2e-140 63