Gene Information

Name : Apre_0354 (Apre_0354)
Accession : YP_003152124.1
Strain : Anaerococcus prevotii DSM 20548
Genome accession: NC_013171
Putative virulence/resistance : Resistance
Product : arsenite-activated ATPase ArsA
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0003
EC number : 3.6.3.16
Position : 403469 - 405211 bp
Length : 1743 bp
Strand : +
Note : KEGG: bca:BCE_A0156 arsenite-translocating ATPase ArsA; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase

DNA sequence :
ATGAAACAATTTGATATCAAGGAAATTGACTTAACTAAATACTTATTTTTCACAGGAAAGGGAGGAGTCGGCAAGACTTC
TACTGCCTGTGCTAGTGCAATAAGTCTAGCTGATGAGGGCAATGAAGTCCTATTAATTAGTACTGACCCTGCTTCAAACC
TTCAAGATGTTTTTGAAACTGAGCTTGATAACAAGGGTGTGAGGATAGAAGGTGTGGATGGACTTACTGTAGCCAACCTA
GATCCTATAGAAGCTGCCAATGAGTATAAGGAAAGTGTAGTTGGTCCCTACAGAGGAAAGTTACCTAAGAGTGTAATAGA
AAATATGGAAGAGCAATTATCTGGATCTTGTACTGTAGAGATAGCTGCTTTTAATGAATTTTCTAAGTTTATAACTGATG
CTGACCTAAAGGACAAATATGATTATATAATATTTGACACAGCACCAACAGGCCACACCCTAAGGATGCTCCAACTTCCT
TCGGCTTGGACGAGCTTTATCAGCGAATCCACCCACGGAGCTTCATGCCTAGGTCAATTATCAGGTCTAGAAGATGAGAA
GGAAACATACAAGTATGCTGTGGATACCCTAGCTGATGGTAAACTTACAAGTCTAGTATTAGTTGCAAGACCTGAGGAGA
CTCCTCTACTTGAAGCAAATAGAGCCTCTTACGAGCTCGCAGAATTAGGTATTAACAATCAAATCCTTATCATAAATGGC
CTATTAAGTGGCCATGATGATGAAGTATCAGAAGCTTTTTATAAAAAGCAAAAAGAATCTTTAGATAAGATGCCAGAAGG
CATTAAGGATCTTAAAACTTTCTTTATTCCACTTAGGGGATACAACTTAAACAGTATCGAAAATTTAAGATCCCTTCTGG
TTGAGGATAAGGAAAATACTAGTGATGTAGACCTTAATATAGGAGAAATTCCAAGGCTAAAAGATATTATAGATGACTTA
TATAAGAATAAGAAAAAAGTTATCTTTACCATGGGAAAGGGCGGTGTAGGAAAGACCACGATGGCATCTGCTATCGCCAA
GGGCCTTACCGCTAAGGGAGAGAAGGTCCATCTAACTACAACCGATCCAGCTAACCACTTGACTGGTATGATTCGTGAAG
ACGACTTATTAACTATAAGCCATATAGATGAAGAAGAAGAGCTTAAAAAATACCAAGAAGAAGTTCTAGAAAATGCTAGA
AAAACCATGTCTGATGAAGACTTGGAGTATATAAAAGAAGATTTAAGATCACCATGTACCCAAGAGATTGCTGTATTTAG
AGCCTTTGCGGATGTGGTTGATAGAGCAGATGATGAGATTGTTGTAATCGATACAGCCCCAACAGGACATACACTTCTGC
TCCTAGATTCTACAGAATCCTATAACAAAGAGATAGAGAAGAACCAAGGCAATGTCCCAGAATCAGCAAAGAAACTTCTC
CCTAGACTAAAAAATAGTGATGAAACAGAAGTCCTAATTGTAACCCTTGCTGAGCCAACTCCATTCTATGAGTCTCAAAG
ACTTGAAGAAGACCTAAAAAGAGCGGGAATTTATAGCAAGTGGTGGATTATAAATTCATCTATATATAAGACTGGCTCTA
GGAACAAGACTCTACAAGCCAAGGCTAATAGTGAGATAGAATGGATAAAAAAGATTGATGATCGTACAGACGGAAACTTC
ACAATAATCCCATGGTCAAGTGATGAGATTAAGGGATCTAGTTTAGATAAATTAATTAAGTAG

Protein sequence :
MKQFDIKEIDLTKYLFFTGKGGVGKTSTACASAISLADEGNEVLLISTDPASNLQDVFETELDNKGVRIEGVDGLTVANL
DPIEAANEYKESVVGPYRGKLPKSVIENMEEQLSGSCTVEIAAFNEFSKFITDADLKDKYDYIIFDTAPTGHTLRMLQLP
SAWTSFISESTHGASCLGQLSGLEDEKETYKYAVDTLADGKLTSLVLVARPEETPLLEANRASYELAELGINNQILIING
LLSGHDDEVSEAFYKKQKESLDKMPEGIKDLKTFFIPLRGYNLNSIENLRSLLVEDKENTSDVDLNIGEIPRLKDIIDDL
YKNKKKVIFTMGKGGVGKTTMASAIAKGLTAKGEKVHLTTTDPANHLTGMIREDDLLTISHIDEEEELKKYQEEVLENAR
KTMSDEDLEYIKEDLRSPCTQEIAVFRAFADVVDRADDEIVVIDTAPTGHTLLLLDSTESYNKEIEKNQGNVPESAKKLL
PRLKNSDETEVLIVTLAEPTPFYESQRLEEDLKRAGIYSKWWIINSSIYKTGSRNKTLQAKANSEIEWIKKIDDRTDGNF
TIIPWSSDEIKGSSLDKLIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsA2 YP_001007632.1 arsenical pump-driving ATPase Not tested YAPI Protein 6e-94 44
SH0111 YP_252026.1 arsenical pump-driving ATPase Not tested SCCmec Protein 8e-100 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Apre_0354 YP_003152124.1 arsenite-activated ATPase ArsA BAC0572 Protein 2e-94 45
Apre_0354 YP_003152124.1 arsenite-activated ATPase ArsA BAC0571 Protein 7e-94 44
Apre_0354 YP_003152124.1 arsenite-activated ATPase ArsA BAC0030 Protein 4e-91 43