Gene Information

Name : Ksed_25630 (Ksed_25630)
Accession : YP_003150290.1
Strain : Kytococcus sedentarius DSM 20547
Genome accession: NC_013169
Putative virulence/resistance : Resistance
Product : alkylmercury lyase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2635337 - 2636020 bp
Length : 684 bp
Strand : +
Note : cleaves the carbon-mercury bond of organomercuric compounds

DNA sequence : 
GTGCTGCGCGTGAACGAACTGGAGGAACCCACGATGTCTGACCTCAGCATGCAACTGCCCGAGCGGCTCAGCCGACTGGG
AGAGACCGGCCTGCTCATCCCGCTGCTGCGGCTGCTCGCCGACGGTGACCCCGTCACCGTCCAACAGCTGTCCGTGGCTG
CGGGCCGCACGATCGACGAGGTACGGCTCGGACTGGCCGCGATGCAGGACACCGAGTACGACGACCAGGGCCGAATCGTC
GGCCAGGGCCTCACGCTGCGCCCTACACCGCACCGGTTCACCGTCGACGGTGAGGAGCTCTACACCTGGTGCGCCCTGGA
CACCCTCATCTTCCCGGCCCTCCTCGATCGCCCAGCGCGCGTGGAGTCCGTCTCCCCGGCCAGCGGAGAGACGATCCGCG
TCACCATCGATCCGGTTGCCGGTGTCACCGGCGTCACACCCCCGAGCGCCGTGGTGTCGCTGGTGAACCTGGAGCAGATC
ACCTCGATCCGCTCGGCCTTCTGCAACCAGGTGCACTATTTCGCCTCCGTCGACGACGCCACCGGGTGGCTCTCTGAGCA
TCCCGGTGCCGAGGTGGTGTCGGTGGCCGAGGCCTACCGGATCGGCAACGAGCTCACAACGAGCCTGCTCGACCTGCTTC
AGGACGACACCCCGGTGGCCGACGACTGTCCCCGCTGCTGTTGA

Protein sequence : 
MLRVNELEEPTMSDLSMQLPERLSRLGETGLLIPLLRLLADGDPVTVQQLSVAAGRTIDEVRLGLAAMQDTEYDDQGRIV
GQGLTLRPTPHRFTVDGEELYTWCALDTLIFPALLDRPARVESVSPASGETIRVTIDPVAGVTGVTPPSAVVSLVNLEQI
TSIRSAFCNQVHYFASVDDATGWLSEHPGAEVVSVAEAYRIGNELTTSLLDLLQDDTPVADDCPRCC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0086 NP_763641.1 alkylmercury lyase Not tested SCCpbp4 Protein 4e-45 44
merB BAB47641.1 organomercurial lyase Not tested Type-III SCCmec Protein 5e-45 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ksed_25630 YP_003150290.1 alkylmercury lyase BAC0663 Protein 2e-46 49
Ksed_25630 YP_003150290.1 alkylmercury lyase BAC0654 Protein 2e-46 49
Ksed_25630 YP_003150290.1 alkylmercury lyase BAC0657 Protein 8e-35 47
Ksed_25630 YP_003150290.1 alkylmercury lyase BAC0659 Protein 3e-34 45
Ksed_25630 YP_003150290.1 alkylmercury lyase BAC0658 Protein 3e-45 44