Gene Information

Name : Ksed_24920 (Ksed_24920)
Accession : YP_003150221.1
Strain : Kytococcus sedentarius DSM 20547
Genome accession: NC_013169
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 2571114 - 2572634 bp
Length : 1521 bp
Strand : -
Note : PFAM: Aldehyde dehydrogenase family

DNA sequence :
ATGACGCAGTACGCCAAGCCGGGGTCCGACGGGTCGCTCATGACCTACAAGGACCGGTACGACAACTTCATCGGGGGCCA
GTGGGTGCCGCCCGTGGGGGGCGAGTACTTCGACGACCCCAGCCCGGTCGACGGGCAGGTCTTCACGCAGGTGGCGCGCT
CGAGTGAGGGCGACGTCGAGAAGGCCCTCGATGCGGCGTGGAAGGCCGCCGAGACGTGGAACCGCACGACGGTGGCCGAG
CGGGCGATCATCCTGAACAAGATCGCCGACCGCATGGAGGAGAAGCTCGAGCAGCTGGCCGTCGCCGAGACCTGGGAGAA
CGGCAAGCCGGTCCGCGAGTGCCTGGCCGCCGACATCCCGCTGGCGATCGACCACTTCCGCTACTTCGCCGGCGTCATCC
GCGCGCAGGAGGGCACCCTCTCCCAGCTCGATGAGGACACGGTCGCCTACCACTTCCACGAGCCGCTCGGCGTGGTCGGG
CAGATCATCCCGTGGAACTTCCCCCTGCTCATGGCCACCTGGAAGCTCGCCCCCGCGCTGGCCGCGGGCAACTGCGTGGT
GATCAAGCCCGCCGAACAGACCCCGGCCTCCATCCTGTTCCTGATGGAGCTGATCGCCGACCTGCTGCCCGACGGCGTCA
TCAACGTGGTGAACGGCTTCGGCGCGGAGGCCGGCAAGGCGCTGGCCTCCAACCCGCGCATCCGCAAGGTGGCCTTCACC
GGTGAGACCACCACCGGCCGGCTGATCATGCAGTACGCCAGCGAGAACCTCATTCCGGTGACCCTGGAGCTGGGTGGCAA
GTCGCCCAACGTGTTCTTCAGCGACGTGATGGACGCCGACGACTCCTACCGCCAGAAGGCGCTGGAGGGCTTCTCGATGT
TCGCCCTGAACTCCGGTGAGGTGTGCACCTGTCCCTCGCGTGCCCTGGTGCAGGAGGACATCGCCGACGAGTTCCTCGAC
CTCGCGGTGGCGCGGGTGAAGAAGATCCAGCGCGGCAATCCGCTGGACACCGACACCATGATCGGCGCCCAGGCCTCCAG
CGACCAGTTCGAGAAGATCACCAGCTACCTGGACATCGGCAGGCAGGAGGGCGCCCAGCTGCTCACCGGCGGCTCGCCCG
CATCGGTCGAGGGCCTGGAGAGCGGCTTCTACGTGGAGCCCACCATCTTCCGCGGGGACAACTCGATGCGGATCTTCCAG
GAGGAGATCTTCGGTCCGGTGCTGGCCGTGACCACGTTCACGGACTTCGACGACGCCATGCGCATCGCGAACGACACGCT
GTACGGCCTCGGCGCCGGCGTGTGGAGCCGCAGCGGAGCCACCGCCTACCGGGCGGGCCGGGCCATCCAGGCCGGGCGCG
TGTGGACGAACTGCTACCACCAGTACCCGGCGCACGCGGCCTTCGGCGGGTACAAGCAGTCCGGCATCGGGCGCGAGAAC
CACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTGGTGAGCTACTCCGACGACCCGGCGGGGCTGTTCTG
A

Protein sequence :
MTQYAKPGSDGSLMTYKDRYDNFIGGQWVPPVGGEYFDDPSPVDGQVFTQVARSSEGDVEKALDAAWKAAETWNRTTVAE
RAIILNKIADRMEEKLEQLAVAETWENGKPVRECLAADIPLAIDHFRYFAGVIRAQEGTLSQLDEDTVAYHFHEPLGVVG
QIIPWNFPLLMATWKLAPALAAGNCVVIKPAEQTPASILFLMELIADLLPDGVINVVNGFGAEAGKALASNPRIRKVAFT
GETTTGRLIMQYASENLIPVTLELGGKSPNVFFSDVMDADDSYRQKALEGFSMFALNSGEVCTCPSRALVQEDIADEFLD
LAVARVKKIQRGNPLDTDTMIGAQASSDQFEKITSYLDIGRQEGAQLLTGGSPASVEGLESGFYVEPTIFRGDNSMRIFQ
EEIFGPVLAVTTFTDFDDAMRIANDTLYGLGAGVWSRSGATAYRAGRAIQAGRVWTNCYHQYPAHAAFGGYKQSGIGREN
HKMMLDHYQQTKNLLVSYSDDPAGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-147 62
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-156 61
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-156 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-156 61
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-155 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ksed_24920 YP_003150221.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 7e-148 62