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Name : leuS (Ksed_17360) Accession : YP_003149513.1 Strain : Kytococcus sedentarius DSM 20547 Genome accession: NC_013169 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 1797996 - 1800950 bp Length : 2955 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAGCGAGAACGACCGCAACGAGACCCCGTTCCGGTACACCCCGCAACTGGCCAACGAGATCGAGGCCCGCTGGCAGGA CCGCTGGGCCGCTGAGGGCACCTTCCGGGCGCCCAACCCCACCGGTGACCTGGCCCCCGCGGACCCCTCCGAGCGCGAGG CCGTCGCCGCCCGCCCGAAGGTGATGATCCAGGACATGTTCCCGTACCCCTCGGGCGCGGGCCTGCACGTGGGCCACCCG CTGGGCTTCATCGCCACCGACGTCTACGCCCGCTACCAGCGCACCACCGGCCGCAACGTCCTCTACACGATGGGCTTCGA CGCTTTCGGCCTGCCCGCGGAGCAGTATGCCGTCGCCACCGGCCAGCACCCGCGCACCACCACCGAGGCCAACATGGAGA CCTACCGCCGGCAGCTGCGCCAGCTGGGTCTGAGCCACGACGACCAGCGCACCTTCGCCACCATCGACCCGGACTACTAC CGCTGGACGCAGTGGATCTTCCTGCAGGTCTACAACTCCTGGTACGACCCCCAGGCCCCGGGTCGCCGCCCCGGCACCAC GGGCCGCGCGCGCCCCATCGAGGAGCTGGAGGCCGCCTACGCGAGCGGCGAGGTGCCCACCCCCGACGGCCGCCCCTGGG ACGAGCTCGATGCGGGGGAGCGCGCCGACGCGGTCGACGCCCGCCGTCTGGCCTACCTGAGCGACGCCCCGGTGAACTGG GTGCCGGGCCTGGGCACGGTGGTGGCCAACGAGGAGGTCACCGCCGACGGCCGTTCGGAGCGTGGCAACTTCCCGGTCTT CAAGCGCAACCTGCCGCAGTGGATGATGCGGATCACCGCTTACGCCGACCGCCTGGTCGATGACCTGGACCGCCTGCAGT GGCCCGAGTCGGTGGCCTCCATGCAGCGCAACTGGATCGGCCGCAGCACCGGCGCCGCCGTGTTCTTCGAGGTGGCCGTC CCCAACGCCGCCTCCCTGCCCGCCGATGCCGACGGCCGCACCCGGCTGGAGGTCTTCACCACCCGCCCGGACACCCTGTT CGGCGCCACCTTCATGGTCGTCGCCCCGGAGCACCCGGTGGCCGATGCGGTGCCGGCCCAGTGGCCGGAGGGCACCGGGG AGGCCTGGACCGGCGGGCACGCCACCCCGGCCGAGGCGGTCGCGGCCTACCGGCAGGCGGCTGCCCGCAAGTCCGACCTG GACCGGCAGGCGGACGACCGCGCCAAGACCGGCGTGTTCACCGGCATCTGGGCCACCAACCCGGTCACCGAGGAGCGTGT GCCGGTGTTCATGGCCGACTACGTGCTGATGGGGTACGGCACCGGAGCGATCATGGCTGTCCCCGCCCAGGACCAGCGCG ACTGGGACTTCGCGACCACCTACGAGCTGCCGATCGTCCGCACCGTGCAGCCCAGCGAGGGCCACGACGAGGACACCGCC TTCACCGGTGAGGGCCCGGCGATCAACTCCGCCAACGAGCAGGTCGACCTGAACGGGCTGGGCGTCGCCGAGGCGAAGGA CCGCATCATCGCCCACCTGGAGTCCACCGGGTCCGGGCACCGCACCATCACCTACAAGCTGCGGGACTGGCTGTTCAGCC GCCAGCGCTACTGGGGTGAGCCCTTCCCCATCGTGTGGGACGCCGACGGCCGCGCCCACGCGGTGCCGGCCGACCAGCTG CCCGTCGAGCTGCCCGAGGTGGCCGACTACAGCCCCAAGACCTACGACCCGGAGGACTGGGACACCCAGCCCGAGTCGCC GCTGGGCCGCAACGCCGACTGGGTGAACGTCACGCTCGACCTGGGAGACGGCCCCCAGCAGTACCGGCGCGAGACCAACA CGATGCCCAACTGGGCTGGCTCCTGCTGGTACGAGCTGCGCTACACCGACCCCACCAACGACCAGGCCTTCGTGGACCCG GCGGTCGAGGAGTACTGGATGGGCCCGGGCCGCGGTTTCGGCGAGGGCGTCGCGGACGACCCCGGCGGCGTGGACCTGTA CGTCGGCGGCGTGGAGCACGCGGTGCTGCACCTGCTGTACGCGCGCTTCTGGCACAAGGTGCTGTTCGACCTGGGCCACC TGAGCTCCGACGAGCCCTTCCGCCGCCTGTTCAACCAGGGCATGGTGCAGGCCTTCGCGTTCCGCGACGACCGGGGCCAG CCGGTGCCGGCGGCGGAGGTCACCGAGACCCAGGCCCCCGACCACCCCCGGGCGCAGAACGGCATCCTGTACGAGTGGGA GGGCCAGCCGGTCACCCGCGAGTACGGGAAGATGGGCAAGTCTCTGAAGAACGTGGTGACGCCGGATGAGATGTGCGCGC AGTACGGCGCGGACGTCTTCCGCGTCTACGAGATGTCGATGGGGCCGCTGGACGCCTCCCGCCCGTGGGAGACGCGGGCC GTGGTGGGTTCGCAGCGCTTCCTGCAGCGGCTGTGGCGCGCGATCGTGGACGAGACCACCGGTGAGCTGCTGGTGACCGA CGACGCCGCCCAGGACGAGACCCTGCGCGCCCTGCACCGCACGATCGCGGGTGTGGCCGACGACTTCGAGAACCTGCGCT TCAACACGGCGGTCTCCAAGCTGATCGAGCTGACGAACACCGTCACCAAGCTGCCGGCCGTGCCGCGTGAGGTGGCCGAG CCGCTCGTGCAGATGGTGGCCCCGCTGGCCCCGCACGTCGCCGAGGAGCTGTGGAGCCGCCTGGGGCACGAGAGCTCCCT GGCCACCGAGCCCTTCCCCCAGGCCGATGAGGCGATGCTGGTGGCCGAGACGGTCACCTGCGTGGTGCAGATCAAGGGCA AGGTCCGTGACCGCCTCGAGGTCTCCCCGGAGATCCCCGCCGACGACCTGGAGGCGCAGGCACTGGCCAGCGAGCGGGTG CAGCAGTTCATCGACGGCGCGCCGGTGCGCAAGGTGATCGTGAAGGCCCCGACCCTCGTCAACATCGTGGTCTGA Protein sequence : MSENDRNETPFRYTPQLANEIEARWQDRWAAEGTFRAPNPTGDLAPADPSEREAVAARPKVMIQDMFPYPSGAGLHVGHP LGFIATDVYARYQRTTGRNVLYTMGFDAFGLPAEQYAVATGQHPRTTTEANMETYRRQLRQLGLSHDDQRTFATIDPDYY RWTQWIFLQVYNSWYDPQAPGRRPGTTGRARPIEELEAAYASGEVPTPDGRPWDELDAGERADAVDARRLAYLSDAPVNW VPGLGTVVANEEVTADGRSERGNFPVFKRNLPQWMMRITAYADRLVDDLDRLQWPESVASMQRNWIGRSTGAAVFFEVAV PNAASLPADADGRTRLEVFTTRPDTLFGATFMVVAPEHPVADAVPAQWPEGTGEAWTGGHATPAEAVAAYRQAAARKSDL DRQADDRAKTGVFTGIWATNPVTEERVPVFMADYVLMGYGTGAIMAVPAQDQRDWDFATTYELPIVRTVQPSEGHDEDTA FTGEGPAINSANEQVDLNGLGVAEAKDRIIAHLESTGSGHRTITYKLRDWLFSRQRYWGEPFPIVWDADGRAHAVPADQL PVELPEVADYSPKTYDPEDWDTQPESPLGRNADWVNVTLDLGDGPQQYRRETNTMPNWAGSCWYELRYTDPTNDQAFVDP AVEEYWMGPGRGFGEGVADDPGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHLSSDEPFRRLFNQGMVQAFAFRDDRGQ PVPAAEVTETQAPDHPRAQNGILYEWEGQPVTREYGKMGKSLKNVVTPDEMCAQYGADVFRVYEMSMGPLDASRPWETRA VVGSQRFLQRLWRAIVDETTGELLVTDDAAQDETLRALHRTIAGVADDFENLRFNTAVSKLIELTNTVTKLPAVPREVAE PLVQMVAPLAPHVAEELWSRLGHESSLATEPFPQADEAMLVAETVTCVVQIKGKVRDRLEVSPEIPADDLEAQALASERV QQFIDGAPVRKVIVKAPTLVNIVV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 4e-142 | 45 |
