Gene Information

Name : lysS (Kkor_0739)
Accession : YP_003145927.1
Strain : Kangiella koreensis DSM 16069
Genome accession: NC_013166
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 766426 - 767925 bp
Length : 1500 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGAGCAATCAAGAAACCCCAGTAGTTGATGTCAACGAGCAGATTACTTTACGTAAGCAGAAGTTGGCAGATAAACGAAA
ACAGGGGATTGCCTTCCCGAACGACTTCCGTCGTGATTCTTTAGCAGCGAATATTGCCAATGAGTATGGCGATAAGGATA
AGGCTGAACTAGAAGAATTGGGTAAACAGGTAAAGGTTGCTGGTCGTATCATGTTGTTCCGCAACATGGGTAAAGCGAGT
TTTATTACTATCCAAGATATGTCAGGCCGCATCCAGTCCTATGTTCGTAAAGATGCGGTAGGCGATGACGTTTATGATGA
TTTTAAAACTTGGGATATTGGTGATATTGTCGGTATTGAAGGTACAGTTTTTAAAACCAATAAAGGCGAGCTATCGGTTA
AAGCATCGAACATTCGTTTGCTGACTAAAGCCTTGCGCCCCCTCCCAGATAAATGGAGTGGCTTGTCGGATCAAGAAACA
CGTTATCGTCAGCGTTACGTTGACCTGATCGTTAATGAAGAGTCGCGCGAAACTTTTATCATTCGTTCAAAAGTGGTTAA
GGCTATTCGTGACTTTTTAGAATCACGTGATTTTCTTGAAGTTGAAACGCCAATGATGCATGTGATTCCAGGCGGAGCAT
CGGCTCGTCCATTTGAAACGCACCATAATGCGCTGGACATGCCACTTTATTTGCGGGTTGCACCAGAATTATATTTAAAG
CGATTGGTTGTAGGTGGCTTAGAAAAAGTTTACGAGATTAACCGCAACTTCCGTAATGAAGGCTTGTCAACGCGTCATAA
CCCAGAGTTCACCATGCTTGAATTCTACTGGGGTTACGCCGATTACAATGACCTGATGGACTTAACTGAAGCCATGTTAC
GCCATACCGTTGAAACGGTTCTAGGTAAAACCGTGTTTGAAAGCAGCGGTGAAACTTACGATTTTGGTAAGCCATTTGCG
CGCATGACAGTGCTGGAAGCTATCACGAAATATCAGCCGGAGATCACTCTTGAACAGCTGAGCGATTTAGATAAAGCTCG
TGATGTTGCTAAGCGTTTAAAAATCAAAACGGAAAAGTCATGGGGCCTGGGTAAAGTTCAAATTGAAATCTTCGAAGAAG
TGGCTGAACACAAATTAATTCAACCAACCTTTATTACAGCTTACCCAGCAGAAGTATCACCGTTAGCGCGTCGTAATGAT
GAAGACCCATTTGTTACCGATCGTTTTGAGTTCTTTGCCGGTGGTCGTGAGTTAGCCAATGGTTTCTCGGAGCTTAATGA
CGCAGAAGATCAGGCGGAGCGTTTCAAAGCACAAGTTGAAGCAAAAGATGCCGGTGATGACGAAGCCATGCACTATGATG
CTGACTACATTCGCGCATTAGAGTATGGCCTTCCACCAACCGCTGGTGAGGGTATTGGTATTGACCGTTTGGTGATGCTG
TTGACGGATTCGCCAAGTATTCGTGATGTTCTATTGTTCCCTCACATGCGACCAGAGTAA

Protein sequence :
MSNQETPVVDVNEQITLRKQKLADKRKQGIAFPNDFRRDSLAANIANEYGDKDKAELEELGKQVKVAGRIMLFRNMGKAS
FITIQDMSGRIQSYVRKDAVGDDVYDDFKTWDIGDIVGIEGTVFKTNKGELSVKASNIRLLTKALRPLPDKWSGLSDQET
RYRQRYVDLIVNEESRETFIIRSKVVKAIRDFLESRDFLEVETPMMHVIPGGASARPFETHHNALDMPLYLRVAPELYLK
RLVVGGLEKVYEINRNFRNEGLSTRHNPEFTMLEFYWGYADYNDLMDLTEAMLRHTVETVLGKTVFESSGETYDFGKPFA
RMTVLEAITKYQPEITLEQLSDLDKARDVAKRLKIKTEKSWGLGKVQIEIFEEVAEHKLIQPTFITAYPAEVSPLARRND
EDPFVTDRFEFFAGGRELANGFSELNDAEDQAERFKAQVEAKDAGDDEAMHYDADYIRALEYGLPPTAGEGIGIDRLVML
LTDSPSIRDVLLFPHMRPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-145 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_003145927.1 lysyl-tRNA synthetase VFG1668 Protein 1e-145 59