Gene Information

Name : Kkor_1269 (Kkor_1269)
Accession : YP_003146455.1
Strain : Kangiella koreensis DSM 16069
Genome accession: NC_013166
Putative virulence/resistance : Resistance
Product : putative mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 1367824 - 1369461 bp
Length : 1638 bp
Strand : -
Note : TIGRFAM: mercuric reductase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; Heavy metal transport/detoxification protein; FAD dependent oxidoreductase; KEGG: shn:Shewa

DNA sequence : 
ATGCGTAAATTCTCCATCTCTGGAATGACTTGTGAAAGATGCCCTCAGCAGATCGAAGATGCCTTGATCGTCATGCCTGG
CGTCAGAAATGCCACCGTTTTTTATACGAAATCCAGTGCAGTCGTCGAAGCAGAATCTGATGTCAATGAACAGACGCTAA
TCAATACCATCAAAGCTCTTGGCTACACGGCTCAACCTGTCGCGTTAGATGGCTGCGATAGTGAAGATGTGACTGACAAA
AAGTCGCTGCATGTCGCTATCATCGGTACTGGCTCGGCTGCTTTTGCTTGTGCTATCAAGGCAGTGGAAAATGGAGCACA
AGTCACACTCGTTGAAGCTGGAGATGTGATCGGAGGTTGTTGTGTTAATGTCGGTTGTGTACCTTCGAAAATTCTGCTCC
GGGCTGCCCAGCTGGCTGAACAGCAGCGTAACAATCCTTTCGACGGTCTAGAAAATCATGAACCTTCTTTGGATCGTAGC
TTGTTAGCGAAACAACAAACTGCACGCGTGGAAGAGTTACGTGCCGCCAAATATCAGCATATTCTGGATACCAATCCAGC
ATTGTCATTGGTACAAGGTTATGCATCTTTTAAAGATACTCATACCTTAACTATTCGCAACAAAGATGGTTACGAGCAAG
AGCTGGTTGCAGATCGCTTTTTGATTGCCAGCGGCAGTCAGCCATCTATTCCTCCTATTCCAGGCCTGGTTGATACCCCT
TATTGGACTTCGACGGAAGCTTTATTCGAAACTGAGCTACCTGAGCACTTGTTAGTGATAGGCTCTTCAGTTGTGGCTGT
CGAACTTGCTCAAGCTTATCGTCGGCTGGGTGCAGAGGTCACTATCTTGGCTCGCAGTACTTTATTGCTCCGTGAAGACC
CACTGTTGGGAGAAGGCTTAACCGTAGCTTTTGAACAGGAAGGCATTCGCGTACTGGAACATACCCAAGCCAGTCAGGTG
TCTTATGAAGATAATAAGTTTATCCTTGATACCGAGCAAGGAGAAATTCGTGGCGATAAATTGCTGGTCGCCACCGGCCG
TGCACCTAATACCGGTAAGCTTAATCTTGCCGCTGCCGGTGTAGAAAAAGAGGCCAATGGAGCGGTCACTGTAGGTGATC
AGATGCGCACATCACAGTCACATATTTACGCAGCAGGTGATTGTAGTAACATGCCGCAACTGGTTTATGTCGCGGCAGCG
GCAGGCAGTCGTGCAGGGATTAACATGACAGGGGGTGAAGCTCGGTTGAATCTATCCGCGATGCCAGCCGTGATCTTTAC
CGAACCGCAGGTAGCAACGGTAGGGTTGTCAGAACAAGAAGCTCATGCACAGAATATTGAGACCGAAAGTCGAGTATTGC
CACTGGAAAACGTGCCTCGAGCACTGGCTAACTTCGACTCTCAGGGTTTCATCAAACTGGTGGTTGAAGCTGGCTCCCAA
CGCCTGATCGGAGCCCAAGTATTAGCTCATGATGGCGGCGAGATTATCCAGAGCGCGGCACTGGCGATTCACAACCACAT
GACAGTGGATGACTTAGCGGATCAATTGTTTCCTTATTTAACTATGGTGGAAGGCCTGAAGCTTTGTGCACAAACTTTCA
GTAAAGATATTAAAGAACTGTCTTGCTGTGCTGGGTAA

Protein sequence : 
MRKFSISGMTCERCPQQIEDALIVMPGVRNATVFYTKSSAVVEAESDVNEQTLINTIKALGYTAQPVALDGCDSEDVTDK
KSLHVAIIGTGSAAFACAIKAVENGAQVTLVEAGDVIGGCCVNVGCVPSKILLRAAQLAEQQRNNPFDGLENHEPSLDRS
LLAKQQTARVEELRAAKYQHILDTNPALSLVQGYASFKDTHTLTIRNKDGYEQELVADRFLIASGSQPSIPPIPGLVDTP
YWTSTEALFETELPEHLLVIGSSVVAVELAQAYRRLGAEVTILARSTLLLREDPLLGEGLTVAFEQEGIRVLEHTQASQV
SYEDNKFILDTEQGEIRGDKLLVATGRAPNTGKLNLAAAGVEKEANGAVTVGDQMRTSQSHIYAAGDCSNMPQLVYVAAA
AGSRAGINMTGGEARLNLSAMPAVIFTEPQVATVGLSEQEAHAQNIETESRVLPLENVPRALANFDSQGFIKLVVEAGSQ
RLIGAQVLAHDGGEIIQSAALAIHNHMTVDDLADQLFPYLTMVEGLKLCAQTFSKDIKELSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 4e-140 60
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 3e-135 59
merA AFG30120.1 MerA Not tested PAGI-2 Protein 3e-135 59
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-138 59
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-138 59
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-138 59
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 4e-135 59
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 4e-134 58
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 3e-134 58
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 3e-129 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kkor_1269 YP_003146455.1 putative mercuric reductase BAC0652 Protein 2e-135 58
Kkor_1269 YP_003146455.1 putative mercuric reductase BAC0653 Protein 3e-137 58
Kkor_1269 YP_003146455.1 putative mercuric reductase BAC0650 Protein 6e-129 56