Gene Information

Name : Shel_27220 (Shel_27220)
Accession : YP_003145069.1
Strain : Slackia heliotrinireducens DSM 20476
Genome accession: NC_013165
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase/cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 3007874 - 3009097 bp
Length : 1224 bp
Strand : +
Note : PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: methionine gamma-lyase

DNA sequence :
ATGAATACAATCGATTGGAGCACCGTGGGATTCTCCACGCTGGCAGTGCACGGCGGCCAGGATCCCGACCCCGCCCACGG
CTCCCTCGCTACCCCTATTTACCAGACGTCCACGTTCTGCTTCGACACCCGCGAAGACGGTACCGCCATCTTCCTGGGTG
AGAAGCCCGGCTTCGCATACTCCCGCGGCGGCAATCCCACCGTACGCGCGCTGGAGACCAAGATCGCCCTGCTCGAAGGC
GGCGAGGAATGCATCGCCACCGCTTCCGGCATGGGCGCCATCAGCTCCGTCCTGCTGACGCTTCTGTCCTCCGGCGACCA
TGTGGTCATGGGCAACTGCGTGTACGGCTGCACCAACGTGGTCATCCAGGAGGTGCTGCCCAAGTTCGGTATCACGATGA
CGGCCGTCGACACCAACGACCTCGCCGCCGTTGAAGCCGCCATCCAGGACAACACGAAGATTCTCTACTTCGAAACCGTC
AGCAACCCTATGACCCGCGTTGCCGACATCGAGGCCCTTTCCGCCCTGGCGAAGGCCCACGGCGTCAAGGTGATCGTGGA
CTCCACCTTCGCCCCCACCCCGCTGGTCCGCCCGCTCGCACTGGGTGCCGACATTGTGGTCCACAGCGCCACCAAGTACC
TCAACGGCCACGGCGACGTGATTGCCGGCCTGATCGTGGGTAAGAAGGAAGACCTGGGCCCCATCAGGACCTACGGCTCC
ACCAAGGCCTGCGGCAGCACACTGAGCCCGCATGACGCATTCCTCGTCCTGCGCGGTCTGCAGACGCTGGGCCTGCGCAT
GGACCGCCATTGCAGCAACGCCATGAAGGTGGCGCAGTTCCTCGAGACCTGCCCCCAGATTCAGACCGTGCTGTACCCTG
GCCTGGAGTCGCACCCCGACCACGACATCGCCGCCAAGCAGTTCAAGAAGGACATGTTCACGGGCATCCTCTCCTTCGAG
ATGAAGGACGGCATCAACGGCATGACCAGCCTTGAAGCCGGCACCCGCATGGTGAACGCCCTCACGATTCCGCACATCGC
CGTGAGCTTGGGCGATCCTTCGTCGCTGGTGGAGCACCCCGCCACCATGACGCATCGCAACGTTCCGCCTCAGGAGCGCG
TGCGCATGGGTATCTCCAACGGCCTCATCCGCTTCTCGGTGGGCTTGGAAGATCCCGAGGACCTCATCGCTGACCTGCAG
CAGGCCCTGGCCACGCTGGACTAA

Protein sequence :
MNTIDWSTVGFSTLAVHGGQDPDPAHGSLATPIYQTSTFCFDTREDGTAIFLGEKPGFAYSRGGNPTVRALETKIALLEG
GEECIATASGMGAISSVLLTLLSSGDHVVMGNCVYGCTNVVIQEVLPKFGITMTAVDTNDLAAVEAAIQDNTKILYFETV
SNPMTRVADIEALSALAKAHGVKVIVDSTFAPTPLVRPLALGADIVVHSATKYLNGHGDVIAGLIVGKKEDLGPIRTYGS
TKACGSTLSPHDAFLVLRGLQTLGLRMDRHCSNAMKVAQFLETCPQIQTVLYPGLESHPDHDIAAKQFKKDMFTGILSFE
MKDGINGMTSLEAGTRMVNALTIPHIAVSLGDPSSLVEHPATMTHRNVPPQERVRMGISNGLIRFSVGLEDPEDLIADLQ
QALATLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-56 42
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-68 41
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-68 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Shel_27220 YP_003145069.1 cystathionine beta-lyase/cystathionine gamma-synthase BAC0207 Protein 3e-86 50