Gene Information

Name : Apre_1763 (Apre_1763)
Accession : YP_003142345.1
Strain :
Genome accession: NC_013164
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 23035 - 24621 bp
Length : 1587 bp
Strand : +
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: bce:BC2304 2,3-dihydroxybenzoate-AMP ligase

DNA sequence :
ATGAACATTGAATTAAAAGAAAAATTAGAAAAAATTTATGATGAACAAGTATGGCCGCATATGACCTTAGGAGAATTTAT
TGAAGATTGTGCTAAAAAATATGGGGATAAAATTGCCTTAGTAGATGGAGATGTTGAACTTTCATATCAAGAATTAAATA
GAAAAGCTTGCCAATATGCCAATGGTTTATTGAAAGCTGGATTTAAAAAGGGAGATAGAATCGTTCTTCAACTTCCTAAT
TGCCATGAATTTGTTATTATCCTTTTTGCCATGTTTAAGATTGGTTTGATTCCTGTATTATCCCTTCCAGCTCACAGGAA
AAATGAAATAAAGGGAATATTAGAAAAATCAGGGGCAATAGCATATATAGCTAAGGGTAAATATCTTGGATTTTCATATG
TGGATATGATTAGAGAAGTAAGAGAAGAATTAAACATAGATTTTAAAGTTTATATTCTTGGGGATAATCAAGGATATAAA
AATTTTTACAATCTCAATGATAAAGATTATATATATCAACATATAGATGTTGACTATAAAGAAATAGGATTATTACTTTT
ATCGGGTGGTACAACTGGGATACCAAAATTGATACCAAGGAGACACTGCGATTATATCTATGTAGCAAAAGAAACTGCAA
AGAGATGTAAAATGGATCAAGACAGTATTTATCTAGCCTCTCTTCCTATTGCTCACAACTTTCCTTTATGTTGCCCAGGG
ATATTAGGAACATTTTTTATAGGCGGCAAAGTTGTTTTATGCCCAGTAACAAGCCCAGATGAAATCTTGCCTTTAATTGA
GGAAGAGGAGGTTACGATAACGGGATTAGTTCCTGCTATGGCAAATATATGTATAGATTTTATAAAGGTAGATGATTATG
ACATATCATCATTAAAGGTTCTTCAAGTTGGAGGTTCGGTTTTAGAAGAAAAGCTTGCAGAAAAAATAGAAAGAGAATTT
GGGTGTAAATTACAACAAATTTTCGGAATAGCTGAAGGTCTGATTATGACAACTTCTTTAGATGATGATAGTAAAACTAT
ATTTACAACTCAAGGTAAACCTATAAGTGAGTTTGATGAATTGTTAATAGTTGATGAAGATGGAGAAGAAGTCAAAGATG
AAGATTACGGAGAACTTATAGTTAGAGGCTCTTACACAATTTATGGCTATTATAAGCTCCCAGAAGTAAATAAAAGATGT
ATAGACAAAGATTTATATTTCAAAACTGGAGATAAGGCAAGGAAACTAAAAGATGGGAATTATCAGGTAGTTGGAAGAAT
TTCAGAAACAATAAATAGGGCTGGAGAAAAAATCACCCCTTCTGAAATTGAAGATATTTTACTATCTAATGAAAATATAG
GAGATGTTCAAGTTGTAGGAGTGCCTGATGAACTTTTGGGAGAAAAAATAGGAGTATTCATATTAAAAGATGAGAAGGAC
GAACTCTCATTAGAAGATATCAGGACATTTCTAGCAAATAAGAATGTAGCGGAATTTAAATTGCCAGATTCTATAAAATA
TATAGATTCATGGCCGCTAACTGCTTTGGGAAAAATTGATAGAAATAAATTAAAAAGAATAGAGTGA

Protein sequence :
MNIELKEKLEKIYDEQVWPHMTLGEFIEDCAKKYGDKIALVDGDVELSYQELNRKACQYANGLLKAGFKKGDRIVLQLPN
CHEFVIILFAMFKIGLIPVLSLPAHRKNEIKGILEKSGAIAYIAKGKYLGFSYVDMIREVREELNIDFKVYILGDNQGYK
NFYNLNDKDYIYQHIDVDYKEIGLLLLSGGTTGIPKLIPRRHCDYIYVAKETAKRCKMDQDSIYLASLPIAHNFPLCCPG
ILGTFFIGGKVVLCPVTSPDEILPLIEEEEVTITGLVPAMANICIDFIKVDDYDISSLKVLQVGGSVLEEKLAEKIEREF
GCKLQQIFGIAEGLIMTTSLDDDSKTIFTTQGKPISEFDELLIVDEDGEEVKDEDYGELIVRGSYTIYGYYKLPEVNKRC
IDKDLYFKTGDKARKLKDGNYQVVGRISETINRAGEKITPSEIEDILLSNENIGDVQVVGVPDELLGEKIGVFILKDEKD
ELSLEDIRTFLANKNVAEFKLPDSIKYIDSWPLTALGKIDRNKLKRIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-84 41
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-84 41
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-84 41
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-84 41
ybtE CAA21394.1 - Virulence HPI Protein 1e-84 41
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-84 41
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 9e-85 41