Gene Information

Name : guaA (Coch_1861)
Accession : YP_003141967.1
Strain : Capnocytophaga ochracea DSM 7271
Genome accession: NC_013162
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2226200 - 2227747 bp
Length : 1548 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAATAAAGATACTTTTCAGGGCTCACGCCTTTTATTGTTAGACTTTGGCTCGCAATACACCCAACTTATTGCACGTCG
TGTGCGCGAATTGAACGTGTATTGCGAAATGCACCCCTACAACCATTTGCCTGAGAACTTAGAAGACTTTTCGGCAGTGA
TACTCTCAGGTTCGCCTTATTCGGTGCGTAGTGCAGAAGCCTTGCACCCAGACCTATCAGCACTGAAAGGTAAAATGCCT
CTTTTGGCAGTATGTTACGGAGCGCAGTATTTGGCACACTTTGGTGGTGGTGAAGTAGCCCCTTCGAACATACGAGAGTA
CGGGCGTGCTCACCTTACCTATATTAAGCCTAATGAACCTCTTTTTGAAGGGATTGCAGAAGGAAGTGTAGTGTGGATGA
GCCATAGTGACACTATCAAACAATTGCCTACTGGGGCGGTTTGTTTGGCGAGCACTCCTGATGTAGTGAACGCTGCTTAT
CGCATAGAAGGAGAAGAAACCTACGCAATTCAGTTTCACCCCGAAGTGACCCACTCAGCCGATGGAATGAAGCTATTAGG
TAACTTCCTTTTCAAAATAGCGAAACTTACCCCTAATTGGACGTCCGACAACTTTGTAGAGATGACAGTTGCCCAGCTAA
AAGCACAAGTGGGTAATGAGAAAGTGATATTAGGCTTATCGGGAGGAGTAGACTCTACGGTAGCTGCTGTATTACTTAAC
AAAGCGATTGGCAAGCAATTACATTGTATTTTTGTAAATAATGGACTCTTGCGCAAAAACGAGTTCGAAAACGTACTGAA
ACAATATGAGGGTATGGGACTGAATGTGAAGGGTGTAGATGCCTCAGCGCGTTTCCTTACTGCCTTAGCAGGCAAAACCG
ACCCCGAGGAGAAACGCAAAATTATAGGGCGCGTTTTTATTGAAGTGTTTGATGATGAAGCTCATAAAATTACTGATGCT
CAATGGTTGGCACAAGGCACTATCTATCCTGACGTGATTGAATCACTATCAGTAAAGGGACCTTCAGCTACTATCAAATC
ACATCATAACGTAGGAGGCTTACCCGACTATATGAAATTGAAAGTAGTAGAGCCTTTGCGTATGCTCTTTAAAGATGAAG
TGCGAAGGGTAGGACGCAGTTTGGGCATCAGTGATGAACTATTAGGCAGACACCCTTTTCCAGGACCTGGATTGGCTATC
CGCATTTTGGGAGATATCACTGCCGAAAAGGTAACTATTTTGCAAGAAGTAGATGCTATATTCATCAACGCACTGAAAGA
AAATAACCTATACGACAAAGTGTGGCAAGCAGGGGCTATTTTACTGCCTATCAACAGTGTGGGAGTAATGGGAGACGAAC
GTACCTACGAGCGTGTGGTAGCCTTGCGCGCTGTGGAAAGCATAGACGGTATGACGGCAGATTGGGTAGACTTACCTTAT
AAATTTCTGCAAAAAGTGTCTAACGATATTATCAATAAGGTGAAAGGCGTAAACCGTGTGGTGTACGATATCAGCAGTAA
ACCGCCTGCCACGATAGAATGGGAATAG

Protein sequence :
MNKDTFQGSRLLLLDFGSQYTQLIARRVRELNVYCEMHPYNHLPENLEDFSAVILSGSPYSVRSAEALHPDLSALKGKMP
LLAVCYGAQYLAHFGGGEVAPSNIREYGRAHLTYIKPNEPLFEGIAEGSVVWMSHSDTIKQLPTGAVCLASTPDVVNAAY
RIEGEETYAIQFHPEVTHSADGMKLLGNFLFKIAKLTPNWTSDNFVEMTVAQLKAQVGNEKVILGLSGGVDSTVAAVLLN
KAIGKQLHCIFVNNGLLRKNEFENVLKQYEGMGLNVKGVDASARFLTALAGKTDPEEKRKIIGRVFIEVFDDEAHKITDA
QWLAQGTIYPDVIESLSVKGPSATIKSHHNVGGLPDYMKLKVVEPLRMLFKDEVRRVGRSLGISDELLGRHPFPGPGLAI
RILGDITAEKVTILQEVDAIFINALKENNLYDKVWQAGAILLPINSVGVMGDERTYERVVALRAVESIDGMTADWVDLPY
KFLQKVSNDIINKVKGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-112 49
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-112 49
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-112 49
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-105 47