Gene Information

Name : lysS (Cyan8802_0883)
Accession : YP_003136654.1
Strain : Cyanothece sp. PCC 8802
Genome accession: NC_013161
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 894574 - 896295 bp
Length : 1722 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCTCCGAATCAACCCCCAAAAGAGCCTCATTCTGCTTCAAGTTTAGAAGAAATTCGCGCTACACGCTTAGAAAAAGT
TGAACAGTTGCAACAATTGGGATTAGTTCCCTACGCCTATAAATGGGAATCTACCCATACGGCAGCCAATTTACAAGATA
AATATGCCACTCTTAAAGATGGGGAAGAAGTTGATCTAGAAGTAGCGATCGCAGGAAGAATTATTGCCCGTCGTGTCTTC
GGAAAATTGGCCTTTTTTAGTCTCCAAGATGAAACCGCAACCATTCAATTATATTTAGATAAACAACAAATTGATACCTC
AATGACTGAGGTGACTGATGCCTTTAATACCCTGAAAAAATTAACCGATACAGGGGATATTTTAGGCGTTGTAGGAACCA
TTAAACGAACGGAAAAGGGAGAACTTTCGGTGAAGGTTCAAACCTATACGATTTTGACGAAATCTTTACTCCCTTTACCC
GATAAATGGCATGGGTTAACGGATACAGAAAAACGCTATCGTCAACGCTACGTCGATTTAATTGTTAATCCCCAAGTTCG
TCAAACTTTTCGCCGTCGGGCTCAAATTACCGCTTCTATTCGTCGTTATTTAGATGAGAACGGCTTTATCGAAATAGAAA
CTCCTGTTTTACAAAGTGAAGCGGGAGGAGCAGAAGCGCGTCCGTTTATTACCTATCATAACACCTTGGATATGGAATTA
TATCTGAGGATTGCTACCGAATTGCATCTAAAACGCTTAATTATTGGCGGCTTTGAAAAGGTGTTTGAATTGGGGCGAAT
TTTCCGTAATGAAGGAGTTTCTACTAAACATAATCCTGAGTTTACTTCCATCGAAGTTTATCAAGCCTACGCCGATTATT
TTGATATGATGGAGTTAACTGAAGCACTTATTACCAATGCCGCTCAAGCCGTTTTAGGCACATTAAAACTTACCTATCAA
GAGATAGAAATTGATTTATCAACCCCTTGGCGACGGGTGACAATGACAGACATTGTTAAAGAAAAAACGGGGTTAGATTT
TGATAGCTTTACTGACTTTGAAAGTGCAAAAGAAGCAGCAAAAAAAGCAGGAATAGACGTTCCTAATGACTGTCCTTCTC
TCGGAAAATTAATGAATGAAGCCTTTGAACAAAAGGTAGAAGAAACCTTAATTCAACCGACTTTTATTCTAGATTTTCCC
GTAGAAATTTCACCCTTAGCAAAACCCCATCGCTCTAAAAAAGGGTTAGTAGAACGTTTTGAATTATACATTGTTGGCCG
AGAATTAGCCAATAGTTTTTCGGAATTAACCGATCCCATCGATCAACGGGAAAGATTAGAAAAACAAGCCGAACAAAAGG
CCTCTGGAGACTTAGAGGCACAAGGAGTTGATGAAGATTTTCTAACCGCTTTGGAATACGGAATGCCTCCGACTGGAGGG
TTAGGCATTGGCATCGATCGCTTAGTTATGTTATTAACTGATTCTCCGAGTATTCGGGATGTAATTGCCTTTCCTCTCTT
AAAAAGTCAGAGTGTTACTGTTAAGTCGTTTGACTATGATGCTGACAAAAAAATTCTTAGGGTTGAATTTACTAATGGCA
GTATTTATCAATACCATGATGTGCCTAAATCTCTCTATCAAGCGTTAGAAAAAGCCCCCTCAAAAGGACAGTTTTTTAAT
GCAGAAATTCGGGATAAATTTGGCTTTGATCGAGAAGTTTAA

Protein sequence :
MSPNQPPKEPHSASSLEEIRATRLEKVEQLQQLGLVPYAYKWESTHTAANLQDKYATLKDGEEVDLEVAIAGRIIARRVF
GKLAFFSLQDETATIQLYLDKQQIDTSMTEVTDAFNTLKKLTDTGDILGVVGTIKRTEKGELSVKVQTYTILTKSLLPLP
DKWHGLTDTEKRYRQRYVDLIVNPQVRQTFRRRAQITASIRRYLDENGFIEIETPVLQSEAGGAEARPFITYHNTLDMEL
YLRIATELHLKRLIIGGFEKVFELGRIFRNEGVSTKHNPEFTSIEVYQAYADYFDMMELTEALITNAAQAVLGTLKLTYQ
EIEIDLSTPWRRVTMTDIVKEKTGLDFDSFTDFESAKEAAKKAGIDVPNDCPSLGKLMNEAFEQKVEETLIQPTFILDFP
VEISPLAKPHRSKKGLVERFELYIVGRELANSFSELTDPIDQRERLEKQAEQKASGDLEAQGVDEDFLTALEYGMPPTGG
LGIGIDRLVMLLTDSPSIRDVIAFPLLKSQSVTVKSFDYDADKKILRVEFTNGSIYQYHDVPKSLYQALEKAPSKGQFFN
AEIRDKFGFDREV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-106 48
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 2e-84 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_003136654.1 lysyl-tRNA synthetase VFG1668 Protein 3e-106 48