Gene Information

Name : guaA (Cyan8802_0722)
Accession : YP_003136496.1
Strain : Cyanothece sp. PCC 8802
Genome accession: NC_013161
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 722277 - 723905 bp
Length : 1629 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGACTACCCAAACTCCCCCCATCACTAACCCGTCTGAGAAATTACCGACTGAGCCGATCAATAAAGCCCTTAACCGTCA
AATGCTGGTGATCCTCGATTTTGGCTCCCAATATTCGGAATTGATCGCTCGTCGTATCCGCGAAACTCAAGTGTATTCCG
AAGTCCTCTCCTATCGGACTACTATCGAGCAAATTCGTCAGCTTAACCCCCGTGGGATTATCCTCTCAGGTGGACCCAAT
TCGGTCTATGATAACCGTGCTCCTCAATGTGATCCCGAAATTTTTCATCTAGGTGTCCCCATCTTGGGCGTTTGCTACGG
AATGCAGTTGATGGTTCAACAACTCGGTGGCCAAGTGGAACGGGCAAAACGCGGAGAATACGGGAAAGCTTCCCTATTTA
TCGATGATCCCACCGATTTACTCACCAACGTCGAAGATGGTTCCACCATGTGGATGAGTCATGGTGACTCCTGTACCCAA
TTGCCGGAAGGGTTCGATATTTTAGCCCATACCGAGAATACTTCCTGCGCTGCGATCGCCCACCACCAAAAGAAACTGTT
TGGCGTACAATTTCACCCCGAAGTCGTCCACTCAGTCGGCGGCATTGCCCTGATTCGTAATTTTGTCTACCATATCTGTC
AATGTGAACCTACTTGGACAACAGAAGCCTTTGTAGAAGAGTCGATTCGGGAAATTCGCGCTAAAGTAGGAGATAAACGG
GTCTTATTAGCGTTATCTGGGGGAGTGGATTCGTCTACCTTAGCCTTTCTCCTCCATCGGGCGATCGGGGATAACCTAAC
TTGTATGTTTATCGATCAGGGGTTCATGCGTAAGGGAGAACCCGAACGATTGGTCGAGATTTTTGATAAACAGTTCCATA
TTCCCGTAGAATACGTTAACGCGAGAACGCGCTTTTTAGAACAATTGGCCGGAGTGACCGATCCCGAAACGAAACGCCGT
TTGATCGGACACGAATTTATTCAAGTCTTTGAAGAAGAGTCGGAACGTCTCGGACCGTTTGATTATTTGGCACAAGGGAC
GCTTTATCCCGATGTTATTGAGTCAGCCGATACCAATGTTGACCCCCAAACGGGCGAAAGAGTGGCAGTTAAGATTAAAA
GTCACCATAATGTGGGGGGATTACCCAAAAATCTGCGGTTTAAGCTGGTAGAACCCCTGCGGAAGTTGTTTAAGGATGAG
GTACGCAAGTTAGGCCGGGCGATCGGTTTACCAGAAGAAATTGTCCGTCGTCATCCGTTTCCCGGTCCAGGGTTAGCTAT
TCGTATTATTGGGGAAGTCACGGCAGAACGCCTGAATATCCTACGGGATGCCGATTTTATCGTCCGTGATGAAATTAGCA
AACAGGGGATGTACCACGATTTTTGGCAAGCGTTCGCGGTTCTTTTACCCGTTCGTAGTGTTGGGGTGATGGGCGATCGC
CGTACCTACGCTCACCCCATTGTTTTACGCTTAATTACTAGCGAAGATGGTATGACGGCAGATTGGGCAAAAGTTCCCTA
TGATTTGCTAGAAACTATCTCTAATCGCATTGTTAATGAGGTAAAAGGGGTTAACCGCGTAGTTTATGATATTACTTCCA
AACCCCCCGGAACTATCGAATGGGAATAA

Protein sequence :
MTTQTPPITNPSEKLPTEPINKALNRQMLVILDFGSQYSELIARRIRETQVYSEVLSYRTTIEQIRQLNPRGIILSGGPN
SVYDNRAPQCDPEIFHLGVPILGVCYGMQLMVQQLGGQVERAKRGEYGKASLFIDDPTDLLTNVEDGSTMWMSHGDSCTQ
LPEGFDILAHTENTSCAAIAHHQKKLFGVQFHPEVVHSVGGIALIRNFVYHICQCEPTWTTEAFVEESIREIRAKVGDKR
VLLALSGGVDSSTLAFLLHRAIGDNLTCMFIDQGFMRKGEPERLVEIFDKQFHIPVEYVNARTRFLEQLAGVTDPETKRR
LIGHEFIQVFEEESERLGPFDYLAQGTLYPDVIESADTNVDPQTGERVAVKIKSHHNVGGLPKNLRFKLVEPLRKLFKDE
VRKLGRAIGLPEEIVRRHPFPGPGLAIRIIGEVTAERLNILRDADFIVRDEISKQGMYHDFWQAFAVLLPVRSVGVMGDR
RTYAHPIVLRLITSEDGMTADWAKVPYDLLETISNRIVNEVKGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-139 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-139 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-139 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-125 51