Gene Information

Name : guaA (Svir_04770)
Accession : YP_003132379.1
Strain : Saccharomonospora viridis DSM 43017
Genome accession: NC_013159
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 469455 - 470999 bp
Length : 1545 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGGCAGACGGTCCCGTGCTCGTGGTGGACTACGGCGCACAGTACGCGCAGCTCATCGCTCGCCGAGTGCGCGAGGCGCA
GGTGTACTCGGAGGTCGTGCCCCATACGACCCCCGTCGCCGAGATCCTCGAGCGTGACCCGGCCGCCATCATCCTGTCGG
GCGGTCCGGCGAGCGTGTACGCCGACGGTGCCCCCGGAGTGGACCCCGTCCTGTTCGACGCGGGAGTGCCGGTGTTCGGC
ATCTGCTACGGCTTCCAGGTCATGGCGAAAGCGCTCGGTGGCACGGTGGAGCACACGGGCACCCGGGAATTCGGACGGAC
CGAACTGGAGGTCGTCGGGGGAACGCTGCATGAGGGGCTGCCCACGCGGCACCCGGTGTGGATGAGTCACGGTGACTGCG
TGACGGAGGCGCCCGAAGGGTTCGAGGTCACGGCGAGCAGTGACGGTGCTCCGGTGGCCGGATTCGAGAACCTCGAACGC
AGGCTCGCCGGAGTGCAGTACCACCCGGAGGTGGCGCATTCACCCCACGGGCAGGAGGTGTTGCGGCGGTTCCTGCACGA
CATCGCGGGGGTGCGGCCGAACTGGACCACGGCGTCGATCGTGGACGAGCAGGTGGAGCGCATCCGCGCTCAGATCGGCG
ACGGACACGCCATCTGCGGTTTGTCCGGTGGGGTGGACTCGGCTGTGGCCGCGGCGCTCGTCCAACGCGCCATCGGTGAC
CGTCTCACCTGTGTGTTCGTGGATCACGGCCTGTTGCGGGCCGGGGAGCGGGCGCAGGTGGAACGTGACTTCGTGGCCGC
CACCGGGGTGAAGCTGGTCACGGTGGACGCCAGTGAGCGGTTCCTGTCTGCGTTGGCCGGGGTCACCGACCCCGAACAGA
AGCGCAAGATCATCGGTCGGGAGTTCATCCGCGTCTTCGAGCAGGCCGCACGTGACGTCAAGGCGGCGGGGGACGTCGAG
TTCCTCGTGCAGGGCACGTTGTACCCCGACGTGGTGGAGTCCGGCGGGGGTGCCGGCACGTCCAACATCAAAAGCCACCA
CAACGTGGGCGGTCTGCCGGACGACCTCCAGTTCACGCTGGTGGAGCCGTTGCGGATGCTGTTCAAGGACGAGGTTCGTC
GGGTGGGCCTCGAACTCGGCCTTCCCGAGACCATCGTGCACCGGCAACCGTTCCCGGGACCGGGACTGGGCATCCGCATC
ATCGGCGAGGTGACCGCCGAACGGCTGGAGATCCTCCGCGCGGCCGACGCCATCGCTCGCGAGGAGATGAGTGCCGCCGA
GCTGGACTCGGACATCTGGCAGTGCCCCGTCGTGCTCCTGGCCAACGTCCGCAGCGTCGGCGTGCAGGGCGACAGCCGTA
CGTACGGACACCCTGTGGTGCTGCGCCCAGTTTCCAGTGAAGACGCCATGACCGCCGATTGGGCTCGGTTACCCTACGAC
GTGCTCGAACGGATCTCCACGCGGATCACCAACGAGGTGGCCGATGTGAACCGGGTCGTGTTGGACGTGACCAGCAAGCC
GCCCGGCACGATCGAGTGGGAGTGA

Protein sequence :
MADGPVLVVDYGAQYAQLIARRVREAQVYSEVVPHTTPVAEILERDPAAIILSGGPASVYADGAPGVDPVLFDAGVPVFG
ICYGFQVMAKALGGTVEHTGTREFGRTELEVVGGTLHEGLPTRHPVWMSHGDCVTEAPEGFEVTASSDGAPVAGFENLER
RLAGVQYHPEVAHSPHGQEVLRRFLHDIAGVRPNWTTASIVDEQVERIRAQIGDGHAICGLSGGVDSAVAAALVQRAIGD
RLTCVFVDHGLLRAGERAQVERDFVAATGVKLVTVDASERFLSALAGVTDPEQKRKIIGREFIRVFEQAARDVKAAGDVE
FLVQGTLYPDVVESGGGAGTSNIKSHHNVGGLPDDLQFTLVEPLRMLFKDEVRRVGLELGLPETIVHRQPFPGPGLGIRI
IGEVTAERLEILRAADAIAREEMSAAELDSDIWQCPVVLLANVRSVGVQGDSRTYGHPVVLRPVSSEDAMTADWARLPYD
VLERISTRITNEVADVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 76
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-141 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-141 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-141 52