Gene Information

Name : leuS (Svir_39550)
Accession : YP_003135724.1
Strain : Saccharomonospora viridis DSM 43017
Genome accession: NC_013159
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 4279108 - 4281957 bp
Length : 2850 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACGGACGGTACCGAAGCGGTTCCGGCACACCGTTACACGGCGGAGCTGGCCGGGCGGATCGAACGACGTTGGCAGGA
GTACTGGGAAGCCAACGGCACCTATCACGCTCCGAACCCGGTGGGCTCGCTCGCCGACAAGGATTCCGAGGTGCCGTCCG
ACAAGTTGTTCGTGCAGGACATGTTCCCGTACCCGTCGGGCGCGGGCCTGCACGTCGGGCATCCGCTGGGCTTCATCGGT
ACCGACGTGTTCGCTCGGTACAACCGCATGATCGGGCGCAACGTGCTCCACACGATGGGGTTCGACGCGTTCGGTCTGCC
GGCCGAGCAGTACGCGGTGCAGACGGGCACGCACCCGCGCACCACCACCGAGGCGAACATCAAGCGGTATCTGGCCCAGA
TCCGCAGGTTGGGTCTGGGGCACGACGAACGGCGGCGGATCGCGACCACCGACGTCGACTACTACCGGTGGACGCAGTGG
ATCTTCCTGCAGATCTTCAACGCCTACTACGACACGGAACAGAACAAGGCGCGGCCGATCTCGGAGCTGGAGAAGGCCTA
CGCCGAGGGAAGGCGGGCCACGCCGGACGGGCGGCCGTGGCACGAGCTGTCGCGTAAGGAACAGCGGGAGATCATCGACT
CGCACCGGTTGGTGTACCTGTCCGAGGCGCCGGTGAACTGGGCTCCCGGCTTGGGCACGGTGGTGGCGAACGAGGAGGTC
ACCGCCGAGGGCCGTACCGAACGGGGCAACTTCCCCGTGTTCCGGCGGAACCTGCGCCAGTGGATGATGCGCATCACGGC
GTACGCCGATCGCCTGCTCGACGACCTGGACCGGCTGGACTGGCCGGAGAAGATCAAGACGATGCAGCGGAACTGGATCG
GCCGGTCGCGTGGTGCGAACGTCCGGTTCCGCTCGGGTGAGCACACCATCGAGGTGTTCACCACGCGTCCCGACACGCTG
TTCGGCGCCACGTACATGGTGTTGGCGCCGGAGCATCCGTTGGTGGACGAGTTGGTGCCCGCCGAGTGGTCCGAGGGGGT
CGACGAGCGGTGGACCGGCGGTGCCGCGACCCCGGGTGAGGCCGTGGCCTCGTATCGGCGGGAGACGTCGCGCAAGTCCG
AGCTCGACCGCCAGGAGAGCAAGGAGAAGACGGGGGTGTTCACCGGGGCGTACGCCACGAACCCGGTGAACGGTAAGCGG
ATCCCCGTGTTCATCGCCGACTACGTGCTGATGGGCTACGGCACCGGCGCGATCATGGCCGTGCCCGGCGAGGATCAGCG
CGACTGGGATTTCGCCACGAAGTTCGGTCTGGACATCCTGCGCACGGTGCAGCCGGGCGAGGACTTCGACGGCGAGGCGT
TCGACGGCGACGGCGCGCACATCAACTCGGCCAACGACGAGATCGATCTCAACGGCCTGAACATCGAGGACGCCAAGAAC
AAGATCATCGAGTGGTTGGAGCACAAGGGCCACGGCGAGGGCACGGTGCAGTACAAGCTGCGCGACTGGCTGTTCGCCCG
CCAGCGGTACTGGGGTGAGCCGTTCCCCATCGTCTACGACTCCGACGGCATGCCGATCGCGCTGCCGGAGGATCAGTTGC
CGGTCGTGCTGCCCGAGGTGGACGACTACTCGCCGAAGACGTTCGACCCGGAGGACGCCGACGCCGAGCCCGAGCCGCCG
CTGGCGCGGGCCACCGACTGGGTCGAGGTGACGCTGGACCTGGGTGACGGGCCGAAGAAGTATTGGCGCGACACCAACGT
GATGCCGCAGTGGGCGGGTTCGTGCTGGTACCAGCTGCGTTACATCGACCCGGACAACGACGAGCGGTTCGTCGACCCGG
TCAACGAGCGTTACTGGATGGGGCCGCGTCCCGAGCTGCACGGTGAGAACGACCCGGGTGGTCTGGACCTGTACGTGGGC
GGGGTGGAGCACGGCGTGCTGCACCTGCTGTACTCGCGGTTCTGGCACAAGGTGCTCTACGACCTGGGCTACGTCTCGTC
GGAGGAGCCGTACCGCAGGCTGTACAACCAGGGCTACATCCAGGCCTACGCCTACACCGACTCCCGCGGTGTGTACGTGC
CCGCCGAGGAGGTGGAAGAACGCGACGGCAAGTTCTTCTACAAGGGCGAGGAGGTCAAGCAGGAGTACGGCAAGATGGGC
AAGAGCCTGAAGAACGTCGTCACTCCTGACGAGATCGCCGAGAACTACGGCGCGGACACGTTCCGGTTCTACGAGATGTC
GATGGGACCGCTGGACGTGTCCAGGCCGTGGGCGACGAAGGACGTGGTGGGCGCCCACCGGTTCCTGCAGCGGCTGTGGC
GGCTGGTGGTGAACGAGAACACCGGCGAGCTGCGGGTGGCCGACACGGAGTTGTCCGAGGAGGACCTGCGCCAGTTGCAC
CGGACGATCGCCGGGGTGCGGGAGGACTACGCGAACCTACGGTTCAACACGGCGGGCGCGAAGCTCATCGAGCTGAACAA
CTACGTGACGAAGACCTACGGTTCGGCGAAGGCGACGCCGCGTGGCCTGGCGGAGCCGTTGGTGTTGATGCTGGCTCCGA
TGTGTCCGCACATCGCCGAGGAGCTGTGGCACCGGCTGGGGCACTCGGAATCGCTGGTGCACGGCCCGTTCCCGACGGTG
GACGAGCGGTACCTGGTGGACGAGACGGTCGAGTACCCGATCCAGGTCAACGGCAAGGTGCGGTCGAGGATGACGGTGCC
CGCGGACGCCGATCAGGAGGAGCTGAAGAAGGCGGCGCTGGCCGACGAGAAGATCGTGGCGGCGTTGGAGGGCGCGGAGC
CTCGCAAGGTCATCGTGGTGCCGGGTCGGCTGGTGAACGTGGTGAAGTGA

Protein sequence :
MTDGTEAVPAHRYTAELAGRIERRWQEYWEANGTYHAPNPVGSLADKDSEVPSDKLFVQDMFPYPSGAGLHVGHPLGFIG
TDVFARYNRMIGRNVLHTMGFDAFGLPAEQYAVQTGTHPRTTTEANIKRYLAQIRRLGLGHDERRRIATTDVDYYRWTQW
IFLQIFNAYYDTEQNKARPISELEKAYAEGRRATPDGRPWHELSRKEQREIIDSHRLVYLSEAPVNWAPGLGTVVANEEV
TAEGRTERGNFPVFRRNLRQWMMRITAYADRLLDDLDRLDWPEKIKTMQRNWIGRSRGANVRFRSGEHTIEVFTTRPDTL
FGATYMVLAPEHPLVDELVPAEWSEGVDERWTGGAATPGEAVASYRRETSRKSELDRQESKEKTGVFTGAYATNPVNGKR
IPVFIADYVLMGYGTGAIMAVPGEDQRDWDFATKFGLDILRTVQPGEDFDGEAFDGDGAHINSANDEIDLNGLNIEDAKN
KIIEWLEHKGHGEGTVQYKLRDWLFARQRYWGEPFPIVYDSDGMPIALPEDQLPVVLPEVDDYSPKTFDPEDADAEPEPP
LARATDWVEVTLDLGDGPKKYWRDTNVMPQWAGSCWYQLRYIDPDNDERFVDPVNERYWMGPRPELHGENDPGGLDLYVG
GVEHGVLHLLYSRFWHKVLYDLGYVSSEEPYRRLYNQGYIQAYAYTDSRGVYVPAEEVEERDGKFFYKGEEVKQEYGKMG
KSLKNVVTPDEIAENYGADTFRFYEMSMGPLDVSRPWATKDVVGAHRFLQRLWRLVVNENTGELRVADTELSEEDLRQLH
RTIAGVREDYANLRFNTAGAKLIELNNYVTKTYGSAKATPRGLAEPLVLMLAPMCPHIAEELWHRLGHSESLVHGPFPTV
DERYLVDETVEYPIQVNGKVRSRMTVPADADQEELKKAALADEKIVAALEGAEPRKVIVVPGRLVNVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-148 49