Gene Information

Name : Svir_34570 (Svir_34570)
Accession : YP_003135247.1
Strain : Saccharomonospora viridis DSM 43017
Genome accession: NC_013159
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3761307 - 3762953 bp
Length : 1647 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
TTGCACGGTGCCGACCGGGAGACCTCCGACGTCAAGCCCACCGTCACCACCGGTCCGATCACCGGTTCCCGCAAGGTCTA
TCTCGAAACCGAGTCAGGACTTCGGGTCCCCGTTCGACGCATCGAGCTGTCGAACGGGGAGCATTTCGACGTCTACGACA
CCTCCGGCCCCTACACCGATCCACAGGCCACAATAGACGTCCACAAAGGACTACCTAAACTGCGGGCCCCGTGGATCGAA
GGCCGGGAGCACAAGACCCAGCTCGGCTGGGCGAAAGCCGGGGTCATCACCCCGGAGATGGAGTTCATCGCCGCACGGGA
ACGCGTCGACCCCGAGTTCGTCCGTTCCGAGGTGGCCCGCGGACGGGCGGTCATCCCCGCCAACCGCAACCACCCCGAGT
CCGAGCCGATGATCATCGGCAAGAACTTCCTCGTCAAGGTCAACGCCAACATGGGCAACTCCGCCGTGTGGTCGTCGGTG
GAGGAGGAGGTCGACAAGATGGTGTGGGCCACCCGTTGGGGTGCCGACACCGTCATGGACCTGTCCACGGGCAAACGTAT
CCACGAGACCCGCGAGTGGATCCTGCGCAACTCCCCCGTCCCCGTCGGGACCGTGCCGATCTACCAGGCGCTGGAGAAGG
TCGGCGGTGATCCGACGAAGCTGTCGTGGGAGGTCTACCGCGACACCGTGATCGAGCAGTGCGAGCAGGGTGTCGACTAC
ATGACCGTCCATGCGGGAGTGTTGCTCCGGTATGTGCCGCTGACCGCCAACCGGGTCACCGGCATCGTCTCCCGCGGCGG
TTCGATCATGGCCGCGTGGTGCCTGGCACACCACAAGGAATCGTTCCTCTACACGCATTTCGAGGAACTGTGCGACATCC
TCCGCGAATACGACGTGACCTTCTCCCTCGGCGACGGCCTGCGCCCGGGCTCCATCGCCGACGCCAACGACCGCGCCCAG
TTCGCCGAGCTGGAGACGTTGGGCGAACTCACCCGCATCGCACGGGAACGCGACGTGCAGGTGATGATCGAAGGCCCGGG
GCACGTGCCCATGCACAAGATCAAGGAGAACGTGGAACGGCAGGAGCGGCTCTGCGACGAGGCGCCGTTCTACACGCTCG
GCCCCCTGGCCACCGACATCGCACCGGCCTACGACCACATCACGTCGGCCATCGGGGCGGCGCAGATCGCCTGGTACGGC
ACGGCGATGCTGTGTTACGTCACGCCGAAGGAACACCTCGGTCTGCCCAACCGGGACGACGTGAAGACCGGTGTCATCTC
GTACAAGATCGCCGCACACGCCGCCGACCTCGCCAAGGGCCACCCGTACGCGCAGGAGTGGGACGACGCGTTGTCGAAGG
CCCGGTTCGAGTTCCGCTGGAACGACCAGTTCAACCTCTCCCTGGACCCGGACACCGCGCGTTCGTTCCATGACGAGACG
CTGCCCGCGGAACCGGCCAAGACGGCGCACTTCTGCTCCATGTGCGGGCCGAAGTTCTGTTCCATGCGCATCACCCAGGA
CGTTCGTGCCTACGCCGAGGAACACGGCCTGACGAGTGTCGAGGCCATCGAGGCGGGCATGCGGGAGAAGTCCCGCGAGT
TCACCGAGAAGGGCGGACAGGTGTATCTACCGGTGGTGGACCGATGA

Protein sequence :
MHGADRETSDVKPTVTTGPITGSRKVYLETESGLRVPVRRIELSNGEHFDVYDTSGPYTDPQATIDVHKGLPKLRAPWIE
GREHKTQLGWAKAGVITPEMEFIAARERVDPEFVRSEVARGRAVIPANRNHPESEPMIIGKNFLVKVNANMGNSAVWSSV
EEEVDKMVWATRWGADTVMDLSTGKRIHETREWILRNSPVPVGTVPIYQALEKVGGDPTKLSWEVYRDTVIEQCEQGVDY
MTVHAGVLLRYVPLTANRVTGIVSRGGSIMAAWCLAHHKESFLYTHFEELCDILREYDVTFSLGDGLRPGSIADANDRAQ
FAELETLGELTRIARERDVQVMIEGPGHVPMHKIKENVERQERLCDEAPFYTLGPLATDIAPAYDHITSAIGAAQIAWYG
TAMLCYVTPKEHLGLPNRDDVKTGVISYKIAAHAADLAKGHPYAQEWDDALSKARFEFRWNDQFNLSLDPDTARSFHDET
LPAEPAKTAHFCSMCGPKFCSMRITQDVRAYAEEHGLTSVEAIEAGMREKSREFTEKGGQVYLPVVDR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 2e-177 64
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 2e-177 64
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 9e-167 60