Gene Information

Name : Svir_31860 (Svir_31860)
Accession : YP_003134986.1
Strain : Saccharomonospora viridis DSM 43017
Genome accession: NC_013159
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 3455008 - 3456171 bp
Length : 1164 bp
Strand : -
Note : PFAM: Cys/Met metabolism PLP-dependent enzyme

DNA sequence :
ATGGTTGCAGACCCCGCCAGCTACGGATTCGAGACACGCGCCATCCACGTCGGGCAGGAACCCGACCCCCGCACCGGCGC
GGTGATCGTGCCGATCTACCAGACCTCCACCTACGCGCAGGACGGTGTCGGTGGCACCCGCGAGGGCGACTACGAGTACT
CGCGGACCGCCAACCCGACCCGTACCGCGCTCGAACAGGCCCTCGCCGCCCTGGAGAACGGCAAGCACGCCCTCGCGTTC
GCCTCGGGCATGGCGGCCAGTGACGCGGTGCTGCGCGTGGCCCTTCGTCCCGGCGATCACCTCATCCTCGGCAACGACGT
CTACGGCGGCACGTTCCGGCTCATCGACAAGGTGCTCACCGAGTGGGGCGTGAACTACAGCATCGCCTCGCTGGGCGATC
TGGACGAGGTCAGGTCGGCCATGCGCCCCGAGACCAAACTCATCTGGTGCGAGTCGCCGACCAACCCGCTGTTGGGTATC
GCCGACATCGCCGCGCTCGCCGAACTCGCCCACGTCGGGGGAGCCAAGCTCGTGGTGGACAACACGTTCGCCACCCCGTA
CCTGCAGACCCCGCTGGAGCTCGGCGCCGACGTCGTCGTGCACTCCACCACCAAGTACCTGGGCGGCCACTCCGACGTCG
TGGGTGGCGCGGTGATCACCAACTCCGACGAGTTGCGGGAGCGACTGTTCTTCCTGCGCAACTCGGCCGGGGCCGTCCCC
AGCCCGTTCGACGCGTGGTTGACGCTCCGCGGCCTCAAGACGTTGGGCGTGCGGATGGAGCGGCACTGCTCCAACGCCGA
ACTCATCGCCGAGACCTTGTCGAAGCACCCGAAGGTCGACCGCGTGTACTACCCGGGCCTTGCCGAGCACCCCGGTCACT
CGCTGGCGGCCAAGCAGATGCGCCGGTTCGGCGGGATGGTGTCGTTCACCCACGTCGACGGTGAACAAGCCGCGTTGGAC
GTGGCTTCCCGGACGAAGCTGTTCATCCTCGCCGAGTCGCTCGGTGGTGTGGAATCACTCATCGAACACCCCGGCCGCAT
GACGCACGCCAGTGTCGCGGGGTCGTTGCTGCAGGTTCCGGGCGAACTGCTGCGACTGTCGGTGGGCATCGAGGACGCCC
ACGACCTGCTCGAAGACCTGCGCAGTGCGCTGGACGCGTCTTAA

Protein sequence :
MVADPASYGFETRAIHVGQEPDPRTGAVIVPIYQTSTYAQDGVGGTREGDYEYSRTANPTRTALEQALAALENGKHALAF
ASGMAASDAVLRVALRPGDHLILGNDVYGGTFRLIDKVLTEWGVNYSIASLGDLDEVRSAMRPETKLIWCESPTNPLLGI
ADIAALAELAHVGGAKLVVDNTFATPYLQTPLELGADVVVHSTTKYLGGHSDVVGGAVITNSDELRERLFFLRNSAGAVP
SPFDAWLTLRGLKTLGVRMERHCSNAELIAETLSKHPKVDRVYYPGLAEHPGHSLAAKQMRRFGGMVSFTHVDGEQAALD
VASRTKLFILAESLGGVESLIEHPGRMTHASVAGSLLQVPGELLRLSVGIEDAHDLLEDLRSALDAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-77 49
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-78 49
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-65 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Svir_31860 YP_003134986.1 cystathionine gamma-lyase BAC0207 Protein 2e-72 47