Gene Information

Name : Svir_24770 (Svir_24770)
Accession : YP_003134298.1
Strain : Saccharomonospora viridis DSM 43017
Genome accession: NC_013159
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2669496 - 2670920 bp
Length : 1425 bp
Strand : -
Note : PFAM: Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase

DNA sequence :
GTGAGTAGACGAGCGAAAATCGTATGCACCCTCGGCCCGGCTACGGCGACGGCGGACAAGGTCCGAGCGCTCGTCGACGC
GGGTATGGACGTGGCGAGGATGAACTTCAGCCACGGTAGTCACAGCGATCACAAACAGGTCTACGACTTGATCAGGGCCG
CTTCGGAGGAAGCCGGCCGAGCGGTGGGCATCATCGCTGACCTGCAGGGCCCGAAGATCCGTTTGGGTACGTTCGCCGGT
GGCCCCGTGGAGTGGCGGACCGGGGACACCGTGCGCATCACGGTGGAGGATGTCGCCGGGACCCACGAGCGTGTCTCCAC
CACCTACAAGGGCTTGGCCAAGGACGCCAAACCAGGGGACCGTCTGCTCGTCGACGACGGCAAGGTCGGTCTCGTGGTCA
AGGACGTCGAAGGCCCTGACGTCGTGTGCGAGGTCACCGAGGGTGGCCCGGTCAGTAACAACAAGGGCGTGTCGCTGCCC
GGCATGGACGTCTCCGTGCCTGCATTGTCTGAAAAGGACACCCAGGACCTGGAATTCGCCCTCGAACTGGGCGTGGACTT
CGTGGCGCTGTCCTTCGTGCGTTCGCCCGCCGACATCGACCTCGTCCACCAGGTGATGGATCGCGTGGGCAAGGGGCGCG
TGCCGGTGATCGCCAAGTTGGAGAAGCCGGAGGCCGTCTCCAACCTCGAGGCGATCGTGCTCGCTTTCGACGGCCTCATG
GTGGCGCGCGGTGACCTGGGAGTGGAGCTGCCGCTGGAACAGGTGCCGCTGGTGCAAAAGCGCGCCATCCAGATCGCGCG
GGAGAACGCCAAGCCGGTGATCGTGGCCACCCAGATGCTCGACTCGATGGTCAACAACTCGCGGCCCACGCGCGCCGAGG
CATCCGACGTCGCCAACGCGGTACTCGACGGCGCCGACGCCGTGATGCTCTCCGGGGAGACGAGCGTCGGTCGGTACCCG
ATCGAGACCGTGCAGACCATGAGCCGCATCGTGCAGGCCGTGGAGGCGGAGATGCCGTCAGTGCCGCCGCTGAGTCACGT
GCCGCGCACCAAGCGGGGCGTCATCTCCTATGCCGCGCGCGACATCGGGGAGCGGCTCAACGCCAAGGCGCTGGTGGCGT
TCACTCAATCCGGTGACACGGTGCGCCGGCTCGCGCGATTGCACACCCGGCTGCCGTTGTTGGCGTTCACACCGTTGGAG
AGTGTGCGCAGGCAGCTCTCCATGACGTGGGGCACCACCGCGCGCCTGGTCGCTCAGGTGGATTCCACCGACCGCATGAT
CGAGCAGGTGGATCACGCGATGCTGGAAACCGGTCGATACCAACGGGGTGACCTGGTGGTCATCGTGGCCGGATCCCCGC
CGGGAACCGTGGGCTCCACCAACCTCATCCGAGTGCATCGCTTGGGTGAAGACGACCTCTCGTGA

Protein sequence :
MSRRAKIVCTLGPATATADKVRALVDAGMDVARMNFSHGSHSDHKQVYDLIRAASEEAGRAVGIIADLQGPKIRLGTFAG
GPVEWRTGDTVRITVEDVAGTHERVSTTYKGLAKDAKPGDRLLVDDGKVGLVVKDVEGPDVVCEVTEGGPVSNNKGVSLP
GMDVSVPALSEKDTQDLEFALELGVDFVALSFVRSPADIDLVHQVMDRVGKGRVPVIAKLEKPEAVSNLEAIVLAFDGLM
VARGDLGVELPLEQVPLVQKRAIQIARENAKPVIVATQMLDSMVNNSRPTRAEASDVANAVLDGADAVMLSGETSVGRYP
IETVQTMSRIVQAVEAEMPSVPPLSHVPRTKRGVISYAARDIGERLNAKALVAFTQSGDTVRRLARLHTRLPLLAFTPLE
SVRRQLSMTWGTTARLVAQVDSTDRMIEQVDHAMLETGRYQRGDLVVIVAGSPPGTVGSTNLIRVHRLGEDDLS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-76 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-76 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-76 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-76 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Svir_24770 YP_003134298.1 pyruvate kinase VFG0479 Protein 9e-77 41