Gene Information

Name : Huta_0933 (Huta_0933)
Accession : YP_003129849.1
Strain : Halorhabdus utahensis DSM 12940
Genome accession: NC_013158
Putative virulence/resistance : Resistance
Product : Cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 899911 - 901095 bp
Length : 1185 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: nph:NP4746A cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lya

DNA sequence :
ATGAGCGAAGAGCACGACAGCGAATTCGTCGGTAGCGCGTTCGAGACGCGGGCGATCCACGCGGGGTGGGAGCCCGATGC
GGAAACAGGAGCGATCATGCCGCCGATCTACGCCTCCTCGACGTTCGCCCAGGACGCCCCCGGAGACCATCGCGGCTACG
AGTACTCCCGGACGGGCAATCCGACGCGGACAGCCCTGGAGGACAACCTCGCCAGCCTCGAAGGAGGATCACACGGCCGG
GCGTTCGCGAGCGGAATGGCCGCGATCAATACGGTCCTGAACCTGCTCGAAGCCGGCGACCACGTCGTCGTCGGTCAGGA
CGTCTACGGCGGCACTCACCGGCTGTTCACGGAGGTCTACGAGGACTACGACCTCGAATTCTCATTCGTCGACGCGACCG
ATCCTGATGCACTCCGTGAAGCGGTCACACCGGCGACCGAGCTCGTCTGGATCGAAACGCCGACGAACCCGCTCATGCGG
GTGCTGGACATCGAGGCCGTCGCGGGCGTCACCCACGCGAACGACGCGCTGCTTTCCGTCGACAACACGTTCGCGACGCC
GTACCTCCAGCGCCCGCTCGAACATGGCGCGGACATCGTGACCCACTCGCTGACGAAATATCTGGGTGGTCACTCCGACG
TCGTCGGCGGCGCACTGTTCACCGACGACGCCGAACTGGACGAGCGACTGGGCTTCTACCAGAACAGCGTCGGGGCGACG
CCGGACCCATTCGCCTGTTTTCTGGTCCTCCGCGGGATCAAGACCCTCCCCGTCAGGATGGACCGCCACTCCGAGACAGC
CATGGGGCTGGCATCGTGGCTCGCCGAGCAACCGGCCGTTGAAACAGTCCACTACCCGGGCCTTTCCACCCACCCACAGC
ACGACGTCGCCGCGCGACAGATGGACGACTACGGCGGGATGGTGAGCGTTGAACTCGACGCGCCGCTAGACGCAGTCGAG
ACGTTCGTTTCGAACACCGAAGTGTTCACGCTGGCAGAAAGTCTCGGGGGCGTCGAGAGCCTGATCGAGCATCCGGCGTC
GATGACTCACGCAGCGGTCCCCCCAGAACAGCGACGACAGAACGGTATCACTGACGGCCTCGTTCGACTCAGCGTCGGTC
TGGAGGGGGTCGAAGATCTCCGGGCAGACCTGCAACAGGCACTGTCAGAAGCGATCGACGGCTGA

Protein sequence :
MSEEHDSEFVGSAFETRAIHAGWEPDAETGAIMPPIYASSTFAQDAPGDHRGYEYSRTGNPTRTALEDNLASLEGGSHGR
AFASGMAAINTVLNLLEAGDHVVVGQDVYGGTHRLFTEVYEDYDLEFSFVDATDPDALREAVTPATELVWIETPTNPLMR
VLDIEAVAGVTHANDALLSVDNTFATPYLQRPLEHGADIVTHSLTKYLGGHSDVVGGALFTDDAELDERLGFYQNSVGAT
PDPFACFLVLRGIKTLPVRMDRHSETAMGLASWLAEQPAVETVHYPGLSTHPQHDVAARQMDDYGGMVSVELDAPLDAVE
TFVSNTEVFTLAESLGGVESLIEHPASMTHAAVPPEQRRQNGITDGLVRLSVGLEGVEDLRADLQQALSEAIDG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-83 49
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-84 49
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-65 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Huta_0933 YP_003129849.1 Cystathionine gamma-synthase BAC0207 Protein 8e-75 46