Gene Information

Name : guaA (Cpin_6854)
Accession : YP_003126456.1
Strain : Chitinophaga pinensis DSM 2588
Genome accession: NC_013132
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 8585121 - 8586659 bp
Length : 1539 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAGAAAAGATACTTATACTCGACTTTGGTTCCCAGTACACGCAGCTGATTGCCCGCAGTATCAGGGAGTTGAACAT
TTATTGTGAGATCAAGCCTTGTCTCGCACCTATTCAGTGGGACGATACGGTGAAAGGCATTATTCTCTCCGGTAGTCCGT
TTTCGGTAAACGATGCCGGTGCTCCGACCGTTGACATAGCTGCCATGGCGGCAAAAGTACCGGTGCTGGGTGTGTGCTAT
GGCGCTCAGCTGACAGCCAAAGTATTTGGCGGTGAAGTAGCTAAAAGCTCCATCCGTGAATACGGTCGCGCCTTTATGGA
CCACGGTAACAAGGAGGAAAAGCTCCTGTATGATATCTCTTCCCGTAGCCAGGTATGGATGAGCCACTCAGATACCATCG
TCAGAATGCCTGAAGGTTTTGAGATCATCGCTCATACCGACAATATCCCGGTTGCTGCTTTCAAATCTGAAACAGTTGCC
AAACACCCTATCCTCGGTCTGCAGTTCCACCCGGAAGTAACGCATTCCCTGGAAGGTAAACAGTTGCTGCGCAACTTCCT
GGTACACATCTGTGGATGTGCACAGGACTGGACACCTGCAGCTTTTGTACAGGAAACGATCGAAAAGATCAAAGCACAGG
TAGGCGATAAGAAAGTAGTAATGGCGCTGAGCGGTGGTGTTGACTCCACTGTAGCGGCAGAACTGATTCACAAAGCCATC
GGCAGCAACCTGTATTGCATATTCGTAGATAACGGCCTGCTCCGTAAAAACGAATTTGAAAACGTACTGGATTCCTATAA
ACATATGGGCCTGAACGTAAAGGGCGTGAACGCAAAAGATCTCTTCTTCGGAGAACTGAAAGGCGTAAGCGATCCTGAAA
AGAAACGTAAGATCATCGGTCGTCTCTTCATCGAGGTATTCCAGCAGGAAGCTACCCTCCTGACAGATATCTCCTTCCTG
GGTCAGGGTACTATCTATCCTGATGTGATCGAATCTGTTTCTGTAAATGGTCCTTCCGTAACCATCAAATCCCACCACAA
CGTAGGTGGTTTACCAGAGAAAATGAACATGGGACTGGTCGAGCCACTGCGCTTCCTCTTCAAAGATGAAGTAAGACGCG
TAGGTCGCGAGATCGGTATCAGCGAAATATTCCTGGGCCGTCATCCTTTCCCTGGTCCGGGTCTGGCTATCCGTATCCTG
GGTGAGATCACCCCGGAGAAAGTAGCCATGCTCCAGGAAGCAGACGCGGTATATATCGACGGACTGCGTGAAGCAGAACT
CTACGATAAAGTATGGCAGGCAGGTACCATCCTGTTGCCGGTACAGAGCGTAGGTGTAATGGGAGATGAAAGAACTTACG
AATTCACCGTTGCACTCCGTGCCGTGACTTCTGTAGATGGTATGACTGCCGACTGGGCACATCTGCCATATGAGTTCCTG
GCAAAAATGTCAAACGATATTATCAATAAAGTGAAAGGGATTAACCGTGTGGTGTACGATATCAGTTCAAAACCACCGGC
TACCATCGAATGGGAATAA

Protein sequence :
MTEKILILDFGSQYTQLIARSIRELNIYCEIKPCLAPIQWDDTVKGIILSGSPFSVNDAGAPTVDIAAMAAKVPVLGVCY
GAQLTAKVFGGEVAKSSIREYGRAFMDHGNKEEKLLYDISSRSQVWMSHSDTIVRMPEGFEIIAHTDNIPVAAFKSETVA
KHPILGLQFHPEVTHSLEGKQLLRNFLVHICGCAQDWTPAAFVQETIEKIKAQVGDKKVVMALSGGVDSTVAAELIHKAI
GSNLYCIFVDNGLLRKNEFENVLDSYKHMGLNVKGVNAKDLFFGELKGVSDPEKKRKIIGRLFIEVFQQEATLLTDISFL
GQGTIYPDVIESVSVNGPSVTIKSHHNVGGLPEKMNMGLVEPLRFLFKDEVRRVGREIGISEIFLGRHPFPGPGLAIRIL
GEITPEKVAMLQEADAVYIDGLREAELYDKVWQAGTILLPVQSVGVMGDERTYEFTVALRAVTSVDGMTADWAHLPYEFL
AKMSNDIINKVKGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-123 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-123 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-123 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-112 47