Gene Information

Name : leuS (Caci_6801)
Accession : YP_003117483.1
Strain : Catenulispora acidiphila DSM 44928
Genome accession: NC_013131
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 7850625 - 7853501 bp
Length : 2877 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGCGAGCAGACCACACAGCCCAAGCCTGCGAGCGACGACCCGAAGTTCCGGTACACCGCCTCCGTAGCGGCCGACAT
CGAGCCGAAGTGGCAGGAGTACTGGGCCGAGAACCACACCTTCGAGGTACCGGACCAGCCGGCCGACACCGCGGAGCCCA
AGGCCTACATCCTGGACATGTTCCCGTATCCCTCCGGCGCCGGCCTGCACGTCGGCCACCCGCTGGGCTACATCGCGACC
GACGTGCTGGGCCGCTACAAGATGATGACCGGCCACAAGGTGCTGCACACGATCGGCTTCGACGCCTTCGGGCTGGCCGC
CGAGCAGTACGCGGTCGAGCACGGCATCCACCCGCGGGTGAGCACCGAGCGCAACATCGCGCGCTACAAGGAGCAGATCC
ACCGCATCGGCTTCGGCCACGACACCCGGCGCGGGGTGTCGACGATCGACGTGTCCTTCTACAAGTGGACGCAGTGGATC
TTCCTGCAGATCTTCAACTCCTGGTACGACGACCAGGCCGACCGGGCGCGCCCGATCAGCATGCTGATCCAGCAGTTCGC
CGACGGCGCCCGCCGCACCCCCGACGGCCGCGCCTGGCAGGCGCTGTCCGGGCAGGAGCAGGCGGCGATCATCGACTCCT
ACCGCCTGGCCTACATCGCCGAGGCGCCGGTGAACTGGTGCCCCGGTCTGGGCACCGTGCTGTCCAACGAGGAGGTCACC
GCCGACGGCCGCTCCGAGCGCGGCAACTTCCCGGTGTTCAAGCGCAACCTGCGCCAGTGGATGATGCGCATCACCAAGTA
CGGCGACCGGCTGCTGGCCGACCTGGACCGGCTGGACTGGCCCGAGCCGATCAAGCTGCAGCAGCGGAACTGGATCGGCC
GCTCCGAGGGCGCTCGCGTGCACTTCGGCGTGACCGCGGTGGACGGCTCGCAGAAGACGATCGAGATCTTCACCACGCGT
CCTGACACGCTGTTCGGCGCCACGTACATGGTGCTGGCGCCGGAGCACGAGCTGGTCGATTCCTTCGTCGCCAAGGAGTG
GCCCGCCGGCACCCGTGAGAAGTGGACCGGCGGGCACGCCACCCCGGCCGAGGCCGTCGCCGCCTACCGCGCGCAGGCCG
CGGCCAAGTCCGAGGTCGAGCGGCAGACCGAGGGCCGGCAGAAGACCGGCGTGTTCACCGGCACGTTCGCGGTGAACCCG
GTCGACGGGCAGGGCGTGCCGGTCTTCATCGCCGACTACGTGCTGATGGGCTACGGCACCGGCGCCATCATGGCGGTGCC
CGCGCACGACCAGCGCGACTTCGAGTTCGCGCAGGCCTTCGACCTGCCGATGCGGATCGTCGTGGCGCCGCCGGCGGACT
GGCCGGTGGACGTGGCGGACTGGACCGAGTCCTATGACTCCAAGACGGCGCAGATTACTGATTCCGCCAACGACGAGATC
ACGCTGGAAGGGCTGCCGGTCCCGGCGGCGATCCGCGCGATCACCGAGTGGCTGCAGGGCAAGGGGATCGGCGAGGGCAC
GGTCACCTACCGGCTGCGCGACTGGCTGTTCTCGCGCCAGCGCTACTGGGGCGAGCCGTTCCCGATCGTCTACCCGGTCA
ACGGTCCGGAGGCCGGGGTCGCCAAGGCGCTGCCGGAGTCGATGCTGCCGCTGGAGCTGCCGGAGGTCGAGGACTTCTCG
CCGAAGACCTTCGAGGCCGGCGACGTCACCAGCGCCCCGGAGCCGCCGCTGGCGCGCGCCGCCGACTGGGTGAACGTCAC
CCTGGACCTGGGCGACGGCCCGCGGCAGTACCACCGCGAGACCAACACCATGCCGCAGTGGGCCGGCTCGTGCTGGTACT
ACCTGCGGTACCTGTCGCCGGGCGACGACACCCGCTTCGTCGACGCCGCCGCCGAGAAGTACTGGATGGGCCCGCAGGAC
GCCGAGGACACCGGCGGCGTGGACCTGTACGTCGGCGGCGCCGAGCACGCGGTGCTGCACCTGCTGTACGCGCGCTTCTG
GCACAAGGTGCTGTTCGACCTGGGGCACGTGACCAGCGCCGAGCCGTTCCGGAAGCTGTACAACCAGGGCATGATCCAGG
GTGCCTCCTACACTGACGCGCGCGGGGTCTACGTCGAGGCCTCCCGCGTCGAGGAGCGCGACGGCGCCTTCACCTACGAG
GGCGAGCAGGTCACGCAGCACTTCGGCAAGATCGGCAAGTCGCTGAAGAACGTCATCTCCCCGGACGACATGATCGACGA
GTACAGCGCCGACACCCTGCGCATCTACGAGATGTCCATGGGCCCGCTGGACATGTCCAAGCCCTGGGACACCCGCGCCT
CGATCGGCAGCTTCCGCTTCCTGCAGCGGCTGTGGCGCAACGTGATCGACGAGGAGACCGGCGAGGTCACGGTCGTGGAC
GCCGAGCCCGACGAGGCGACCCTGCGCGCCCTGCACAAGACCATCGACGGCGCCCGCGCCGACATGGAGGGCATGCGCTT
CAACACCGCGATCAGCAAGCTGATCGAGCTGAACAACCACCTGACCCGCCTGCCCGCCGTCCCGCGCTCGGCAGCCGAGG
CCCTGGTGGTCCTGACCGCGCCCTTCGCCCCCCACATCGCCGAGGAACTGTGGTCCCGCCTGGGCCACGACGGCTCGGTG
GCCCGCGCCGCCTACCCGGTCGCGAACCCGGCGTACCTGGTCGACGAGACGGTGACCTGCGTCGTCCAGGTCGCCGGCAA
GGTGAAGGACCGCCTGGAGGTGCCTCCGGGCATCGCCCAGGACGCCCTGCGCGAGCTGGCCCTGGCCTCCGAAGGCGTGC
AGCGCGCGCTGGAGGGCCGCGGCGTGCGCGCGGTGATCGTCCGGGCGCCGAAGCTGGTGAACGTGGTCCCGGCGTAG

Protein sequence :
MSEQTTQPKPASDDPKFRYTASVAADIEPKWQEYWAENHTFEVPDQPADTAEPKAYILDMFPYPSGAGLHVGHPLGYIAT
DVLGRYKMMTGHKVLHTIGFDAFGLAAEQYAVEHGIHPRVSTERNIARYKEQIHRIGFGHDTRRGVSTIDVSFYKWTQWI
FLQIFNSWYDDQADRARPISMLIQQFADGARRTPDGRAWQALSGQEQAAIIDSYRLAYIAEAPVNWCPGLGTVLSNEEVT
ADGRSERGNFPVFKRNLRQWMMRITKYGDRLLADLDRLDWPEPIKLQQRNWIGRSEGARVHFGVTAVDGSQKTIEIFTTR
PDTLFGATYMVLAPEHELVDSFVAKEWPAGTREKWTGGHATPAEAVAAYRAQAAAKSEVERQTEGRQKTGVFTGTFAVNP
VDGQGVPVFIADYVLMGYGTGAIMAVPAHDQRDFEFAQAFDLPMRIVVAPPADWPVDVADWTESYDSKTAQITDSANDEI
TLEGLPVPAAIRAITEWLQGKGIGEGTVTYRLRDWLFSRQRYWGEPFPIVYPVNGPEAGVAKALPESMLPLELPEVEDFS
PKTFEAGDVTSAPEPPLARAADWVNVTLDLGDGPRQYHRETNTMPQWAGSCWYYLRYLSPGDDTRFVDAAAEKYWMGPQD
AEDTGGVDLYVGGAEHAVLHLLYARFWHKVLFDLGHVTSAEPFRKLYNQGMIQGASYTDARGVYVEASRVEERDGAFTYE
GEQVTQHFGKIGKSLKNVISPDDMIDEYSADTLRIYEMSMGPLDMSKPWDTRASIGSFRFLQRLWRNVIDEETGEVTVVD
AEPDEATLRALHKTIDGARADMEGMRFNTAISKLIELNNHLTRLPAVPRSAAEALVVLTAPFAPHIAEELWSRLGHDGSV
ARAAYPVANPAYLVDETVTCVVQVAGKVKDRLEVPPGIAQDALRELALASEGVQRALEGRGVRAVIVRAPKLVNVVPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-139 46