Gene Information

Name : Caci_0658 (Caci_0658)
Accession : YP_003111435.1
Strain : Catenulispora acidiphila DSM 44928
Genome accession: NC_013131
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 763036 - 764199 bp
Length : 1164 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGTCCGCATCTGACGCCCACGCCAACGCCGCCTTCGAGACCCTGGCCATCCATGCCGGCCAGGACCCGGACCCGCTGAC
CGGCGCCGTCGTCCCCCCGATCTACCAGGTCTCCACCTACAAACAGGATGGAGTCGGCGGCCTGCGGGGCGGCTACGAGT
ACTCACGCAGCGCCAATCCGACCCGCAAGGCGCTGGAAGACTGTCTGGCCGCCATCGAGGGCGGCCGTGTCGGCCTCGCC
TTCGCCTCGGGTCTGGCCGCTGAGGACTGCCTGCTGCGGACCGTGTGTGTGCCCGGCGACCACGTCGTCATCCCGGCCGA
CGCCTACGGCGGCACCTTCCGCCTGTTCTCCAAGGTCCTGTCGCGGTGGGGTCTGGGCTGGACCGCCGCCAACATGGCGG
ACCCGGCTGCCGTGCGGGCCGCCGTCGTGCCGGGCAAGACCAAGGCGATCTGGGTCGAGACCCCCTCCAACCCGCTGTTG
GGCGTCGCGGACATCGCCGCGCTGGCCGGGGTCGCGCACGAGACCGGCTCGCTGCTGGTCGTCGACAACACGTTCGCCAC
GCCCTACCTGCAGCAGCCGCTGGCGCTCGGCGCCGACGTGATCGTGCACTCCACCACCAAGTACATGGGCGGCCACTCCG
ACGTGGTCGGCGGCGCCCTGGTGGTGTCCGACGAGGAACTCGGCGCGGAGCTGACCTACCACCAGAACGCGATGGGCGCC
GTCGCCGGCCCGTTCGACGCCTGGCTGGTGCTGCGCGGCATCAAGACCCTGGCGGTGCGCATGGACCGGCACTGCTCCAA
CGCGCAGCGCATCGCCGAGGCGCTGGCCGCGCACCCGAAGGTCACCGCCGTCCACTACCCGGGCCTGCCCGACGACCCCG
GCCACGAGGTCGCCGCCAAGCAGATGGCCGGTTTCGGCGGGATGGTCTCCTTCCGGGTGGCCGGCGGCGAGCAGGAGGCG
GTCGACGTGTGCGGCCGCACCGAGCTGTTCATCCTCGGCGAGTCGCTCGGCGGCGTCGAGTCGCTGATCGAGCACCCCGG
CCGGATGACCCACGCCAGCGCCGCCGGCTCGCCGCTGGAGGTCCCGGACGACCTCATCCGGCTCTCGGTCGGCATCGAGT
CGATCGACGACCTGCTGGCCGACCTCCTGCGGGCGCTGGGCTGA

Protein sequence :
MSASDAHANAAFETLAIHAGQDPDPLTGAVVPPIYQVSTYKQDGVGGLRGGYEYSRSANPTRKALEDCLAAIEGGRVGLA
FASGLAAEDCLLRTVCVPGDHVVIPADAYGGTFRLFSKVLSRWGLGWTAANMADPAAVRAAVVPGKTKAIWVETPSNPLL
GVADIAALAGVAHETGSLLVVDNTFATPYLQQPLALGADVIVHSTTKYMGGHSDVVGGALVVSDEELGAELTYHQNAMGA
VAGPFDAWLVLRGIKTLAVRMDRHCSNAQRIAEALAAHPKVTAVHYPGLPDDPGHEVAAKQMAGFGGMVSFRVAGGEQEA
VDVCGRTELFILGESLGGVESLIEHPGRMTHASAAGSPLEVPDDLIRLSVGIESIDDLLADLLRALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-67 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-68 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-53 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Caci_0658 YP_003111435.1 cystathionine gamma-synthase BAC0207 Protein 5e-57 44