Gene Information

Name : Caci_5794 (Caci_5794)
Accession : YP_003116493.1
Strain : Catenulispora acidiphila DSM 44928
Genome accession: NC_013131
Putative virulence/resistance : Resistance
Product : D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : -
Position : 6694108 - 6695094 bp
Length : 987 bp
Strand : -
Note : PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: fre:Franean1_7138 D-isomer specific 2- hydroxyacid dehydrogenase NAD-binding

DNA sequence :
ATGACCTCATCCCCGACGCTCCCCACTCCGGGAATCACTGTCTACGGGTGCGGACAGGACGAGGCTGTCTTGTTCCGAGC
GCTGGCAACGAGATTCGGCTTCGTTCCTACCATTACCGAGGCGGCGGTATCCGAAGCCAACGCAGAACTGGCGTCGGGAA
ACCGATGCATCAGCGTCGGTCATAAGACACAGATCACTGACGCCACACTTCTCGCACTCAGCCGCGTTGGCGTCACCTAC
ATCTCGACCAGAAGCATCGGCTACAACCACCTCGATGTGGGGTTCGCGAACAGCGTCGGCATCTCAGTGGAGAACGTCAG
CTATTCGCCCGACAGCGTTGCCGACTACACCCTGATGTTGATGCTGATGGCGGTCCGCCACGCGAAATCCCTAGTCCGCC
GCACCGACGTCCACGACTACCGTCTTCACGATGTCCGTGGCCGCGAGCTGCGCGACCTGACCGTCGGCGTGGTCGGGACC
GGACGCATCGGCGCAGCCGTCGTGGACCGGCTCAAAGGCTTCGGCTGCCGTGTGATGGCCCACGATCGCAACCCCGAAAG
CGTGGCCGGCTATGCGCCGCTCGACGAGCTCCTACGACACAGCGACATCGTCACGCTCCACACGCCGCTCACCGCTGAAA
CGCACCATCTCCTGAACAGCGAACGGATCGAGCAGATGAAACCCGGCGTCTTCATCGTCAACACCGGACGCGGTTCTCTT
CTCGACACCGAAGCCCTTCTCCAAGCGCTGGAAAGCGGCAGATTGGGCGGCGCGGCGCTAGACGTTCTGGAAGGTGAGGA
AGGGATCTTCTACGCCGACTGTCGAGACAGAGTCATCGAAAGTAAAACACTGCTGCGGTTACAAGAACTCCCGAACGTAC
TCGTCAGTCCGCACACGGCTTACTACACCGATCACGCACTCAGTGACACCGTCGAGAACTCCATTATCAACTGTCTGAGA
TTCGAGAGCGGGAATCATCATGGATAA

Protein sequence :
MTSSPTLPTPGITVYGCGQDEAVLFRALATRFGFVPTITEAAVSEANAELASGNRCISVGHKTQITDATLLALSRVGVTY
ISTRSIGYNHLDVGFANSVGISVENVSYSPDSVADYTLMLMLMAVRHAKSLVRRTDVHDYRLHDVRGRELRDLTVGVVGT
GRIGAAVVDRLKGFGCRVMAHDRNPESVAGYAPLDELLRHSDIVTLHTPLTAETHHLLNSERIEQMKPGVFIVNTGRGSL
LDTEALLQALESGRLGGAALDVLEGEEGIFYADCRDRVIESKTLLRLQELPNVLVSPHTAYYTDHALSDTVENSIINCLR
FESGNHHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 2e-94 59
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 3e-93 58

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Caci_5794 YP_003116493.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit AF155139.2.orf4.gene Protein 6e-100 61
Caci_5794 YP_003116493.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit NC_005054.2598279.p0 Protein 9e-99 60
Caci_5794 YP_003116493.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit NC_014475.1.orf2.gen Protein 9e-99 60
Caci_5794 YP_003116493.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit U35369.1.gene5.p01 Protein 1e-94 59
Caci_5794 YP_003116493.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit AF310956.2.orf4.gene Protein 6e-94 58
Caci_5794 YP_003116493.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit FJ349556.1.orf3.gene Protein 4e-94 58
Caci_5794 YP_003116493.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding subunit AF130997.1.orf3.gene Protein 3e-84 55