Gene Information

Name : Caci_5699 (Caci_5699)
Accession : YP_003116398.1
Strain : Catenulispora acidiphila DSM 44928
Genome accession: NC_013131
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 6574722 - 6576203 bp
Length : 1482 bp
Strand : -
Note : KEGG: sma:SAV_6217 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta

DNA sequence :
ATGCGCCGCGCGAAAATCGTTTGTACCCTGGGCCCGTCGGCCGGAAGCCTGGAGCAGCTCACTGCCCTGGTGGACGCCGG
AATGAACGTGGCCCGCCTGAATCTCTCCCACGGTTCCTATGAGGACCACGAGGAGCGATATCGCAATGTCCGGCAGGTCG
CCACGACCAGCGGTCAGGCGATCGGCATCCTGGTCGACCTGCAGGGCCCGAAGATCCGCCTGGGCACCTTCGCCAACGGC
AAGGAGGTCCTGGCCAACGGCGCGCAGTTCACGATCACCACGCGCGACGTCGCCGGGGACGCCACCATCTGCGGGACCAC
CTACAAGGGACTGCCCGGGGACTGCCGGCCCGGCGACCAGATCCTGGTCGACGACGGCAAGCTGTGCCTGGAAGTGCAGA
GCGTCACCGACACCGACGTGGTGACCCGGGTCGTCGAGGGCGGCCCGATCTCCAACAGCAAGGGCATCAACCTGCCCGGC
GTGTCCGTGTCGGTCCCGGCCCTGTCCGAGAAGGACGAGCTGGACCTGCGCTGGGCCCTGGGCAAGCCGGAGACCGGCCA
CGGCAACCCCGGCGTGCGCGCCGACATGATCGCGCTGTCCTTCGTGCGCGACGCCGTCGACATCGAGCGCGTCCACGAGA
TCATGGACGAGATCGGCCACCGGGTCCCGGTGATCGCCAAGATCGAGAAGCCGCAGGCGGTGGCCAACCTGGACGCCATC
GTCGACGCCTTCGACGCGATCATGGTGGCCCGCGGCGACCTGGGCGTGGAGCTGCCGCTGGAGCAGGTCCCGATGGTGCA
GAAGCGCTGCATCACCCTCTCGCGCCGCAACGCCAAGCCGGTCATCGTGGCCACCCAGATGCTGGACTCGATGATCACCA
ACTCCCGGCCCACCCGCGCCGAGGTGTCCGACGTGGCCAACGCGGTCCTGGACGGCACCGACGCGGTGATGCTCTCGGCC
GAGACCTCGGTCGGCGCCTACGCGGTGCAGACCGTGGAGACGATGGCGAAGATCATCACCGCGGCCGAGGAGGAGACCCT
CGCCGCCGGGCTCAAGCCGGCCCTGAGCAAGCCCCGCACCAAGGGCGGCGCGGTCGCCCGGGCGGCCGCCGAACTCAGCG
AGAACCTCTACGCCAAGTACCTGGTCGCCTTCACCGAGAGCGGCGACACCGCCCGCCGGCTGTCCCGCTACCGTCCCCCG
ACGCCGCTGATCGCCTTCACCCCGCACAACGAGATCCGCAACCAGCTGGCGCTGAGCTGGGGCATCCGGACCTTCTGCAG
CCCCGAGGTCGAGCACACCGACGACATGGTGCGCCAGGTCGACACCGAGCTGCTGCAGCTGGAGCTGAGCAAGACCGGCG
ACACCGTGGTCATCATCGCCGGCTCCCCGCCCGGAATCCCCGGCTCCACCAACGCGGTGCGCGTGCACCGCGTGGGCGAC
GCCATCAACGGCGTCGTGCCGGCCTACCGCGCGGGGCAGTAG

Protein sequence :
MRRAKIVCTLGPSAGSLEQLTALVDAGMNVARLNLSHGSYEDHEERYRNVRQVATTSGQAIGILVDLQGPKIRLGTFANG
KEVLANGAQFTITTRDVAGDATICGTTYKGLPGDCRPGDQILVDDGKLCLEVQSVTDTDVVTRVVEGGPISNSKGINLPG
VSVSVPALSEKDELDLRWALGKPETGHGNPGVRADMIALSFVRDAVDIERVHEIMDEIGHRVPVIAKIEKPQAVANLDAI
VDAFDAIMVARGDLGVELPLEQVPMVQKRCITLSRRNAKPVIVATQMLDSMITNSRPTRAEVSDVANAVLDGTDAVMLSA
ETSVGAYAVQTVETMAKIITAAEEETLAAGLKPALSKPRTKGGAVARAAAELSENLYAKYLVAFTESGDTARRLSRYRPP
TPLIAFTPHNEIRNQLALSWGIRTFCSPEVEHTDDMVRQVDTELLQLELSKTGDTVVIIAGSPPGIPGSTNAVRVHRVGD
AINGVVPAYRAGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-70 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-70 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-70 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 7e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Caci_5699 YP_003116398.1 pyruvate kinase VFG0479 Protein 2e-70 42