Gene Information

Name : Caci_0245 (Caci_0245)
Accession : YP_003111039.1
Strain : Catenulispora acidiphila DSM 44928
Genome accession: NC_013131
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 274186 - 275463 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGACCTGCGACTCCTGCGCACAGACCCGGAGCGTGTCCGCGCCTCGCAGCGCGCCCGAGGTGAAGATCCGGCCCT
CGTCGACGCGCTGCTGTCCGCGGACGAGGCGCGCCGCGCTGCCGTCTCCCGCTTCGACACGCTGCGCAACGAGCAGAAGG
TGCTCGGCAAGCAGATCCCGAAGGCCGCGGGCGAGGAGAAGGCCGCGCTGCTCGAGCAGGCCAAGAAGCTCGCCGACGGC
GTGAAGGCGGCCGAGGCCGACCAGCACGAGGCCGACGACGTGCTCAAGCAGCTCCAGCTCTCGCTGTCGAACGTGGTCAT
CGACGGCGTGCCCGAGGGCGGCGAGGACGACTTCGTCCTGCGCGAGACCGTCGGGACCCCGCGCGACTTCGCCGCCGACG
GCTTCGAGCCGCGCGACCACGTCGAGCTGGGCAAGCTGCTCGGCGCGATCGACCTGGAGCGCGGCGTGAAGGTCGGCGGC
GCGCGGCAGTACTACCTGACCGGCGTCGGCGCGCTGCTGGAGATCGCGCTGCTGAACATGGCGATGGCGCAGGCGACCAC
GTACGGCTTCACCCCGATGATCACCCCGTCGCTGGTGAAGCCGGAGGCGATGGCCGGCACCGGATTCCTGGGCCAGGCCG
CCGAGAACGTCTACCACCTGACCGAAGACGACATGTACCTGGTCGGCACCTCGGAGGTGCCGCTGGCGGCGTACCACATG
GACGAGATCCTGGACGCCGCCAAACTGCCGCTGCGCTACGCCGGCTACTCGTCGTGCTACCGCCGCGAGGCCGGCAGCTA
CGGCAAGGACACCCGCGGCATCATCCGGGTGCACCAGTTCGAGAAGGTCGAGATGTTCTCCTACGTCCTGCCCGAGGAGG
CCGAGGCCGAGCACCTGCGCCTGCTGGGCTGGGAGAAGGAGTTCCTCACCGCGCTGGAGATCCCCTTCCGGGTGATCGAC
GTCGCGGCCGGCGACCTGGGCAGCTCGGCGGCCCGCAAGTACGACTGCGAGGCCTGGATCCCCACTCAGGGCAAGTACCG
CGAGGTCACCTCGACCTCGAACTGCACCGAGTTCCAGGCCCGCCGCCTGCAGATCCGGATGCGTGGCGCCGACGGCGTGA
AGCCGCTGGCGACGCTGAACGGCACGCTGTGCGCGATGACCCGGATGATCGTGGCGATCCTGGAGAACCACCAGAACGCC
GACGGCTCGGTGACGGTTCCGGCGGCGCTGCGGCCCTACCTCGGCGGACGCGAGAAGCTGGAGCCCGTCGCGGGCTGA

Protein sequence :
MIDLRLLRTDPERVRASQRARGEDPALVDALLSADEARRAAVSRFDTLRNEQKVLGKQIPKAAGEEKAALLEQAKKLADG
VKAAEADQHEADDVLKQLQLSLSNVVIDGVPEGGEDDFVLRETVGTPRDFAADGFEPRDHVELGKLLGAIDLERGVKVGG
ARQYYLTGVGALLEIALLNMAMAQATTYGFTPMITPSLVKPEAMAGTGFLGQAAENVYHLTEDDMYLVGTSEVPLAAYHM
DEILDAAKLPLRYAGYSSCYRREAGSYGKDTRGIIRVHQFEKVEMFSYVLPEEAEAEHLRLLGWEKEFLTALEIPFRVID
VAAGDLGSSAARKYDCEAWIPTQGKYREVTSTSNCTEFQARRLQIRMRGADGVKPLATLNGTLCAMTRMIVAILENHQNA
DGSVTVPAALRPYLGGREKLEPVAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-68 42