Gene Information

Name : guaA (Caci_1506)
Accession : YP_003112268.1
Strain : Catenulispora acidiphila DSM 44928
Genome accession: NC_013131
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1710573 - 1712144 bp
Length : 1572 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGAGCAGCCTGCCGACACCGTTCTTGTCATCGACTTCGGGGCCCAGTACGCGCAGCTCATCGCGCGCCGGGTCCGTGA
AGCCCACGTCTACAGCGAGATCGTGCCGCACACCGCGACGGTCGCCGAGATCCTCGCCAAGAAGCCCAAGGCGGTGATCC
TGTCCGGCGGGCCGTCCTCGGTCTACGCCGACGGGGCGCCGAACGTCGGCGCGGAGCTGTTCCGCGCCGGGGTGCCGACC
CTCGGCATCTGTTACGGCTTCCAGGCGATGGCGCGCGCCCTCGGCGGCGTGGTCGAGCAGACCGGCGGCCGGGAGTACGG
CCGCACCTCGCTGGAGGTCACCGACACCGAGTCCACGCTGTTCCAGGGCTCGCACTCCGAGCAGCCGGTGTGGATGTCGC
ACGGCGACGCGGTCGTGGCCGCCCCCGAGGGCTTCCGGGTCACCGGGACCACAGCCAAGACCCCGGTCGCGGCGTTCGAG
GACGACGAGAAGCGGCTCTACGGCGTCCAGCACCACCCCGAGGTCCTGCACTCGCAGTTCGGGCAGCTGCTGCTGGAGAA
CTTCCTCTACAAGGGCGCCGGCATCGCGCCGGACTGGACCACCGGCAACATCGTCGAGGAGCAGGTCGCCTCGATCCGCG
AGCAGGTCGGCACCAAGCGCGCCATCTGCGGGCTGTCCGGCGGCGTGGACTCCGCGGTCGCCGCGGCCATCGTGCAGAAG
GCGGTCGGCGAGCAGCTCACCTGCGTGTTCGTCGACCACGGCCTGCTGCGCAAGGGGGAGGCCGAGCAAGTCGAGAAGGA
CTTCGTCGCGGCGACCGGCGTGCAGTTGAAGGTCGTCGACGCCGAGCAGCGCTTCCTGTCGGCGCTGGCCGGGGTGTCCG
ACCCCGAGGAGAAGCGCAAGATCATCGGCCGCGAGTTCATCCGGGTCTTCGAGCAGGCCGAGCGGGAGATCGTCGAACAG
TCGGCGGACGCCGGCGAGCCGGTGCGCTTCCTGGTGCAGGGCACGCTCTACCCCGACGTCGTGGAGTCCGGCGGCGGCAC
CGGCGCGGCGAACATCAAGAGCCACCACAACGTCGGCGGGCTGCCGGACGACTTGCAGTTCGAGCTGATCGAGCCGCTGC
GCAAGCTGTTCAAGGACGAGGTCCGGCAGGTCGGCCGCGAGCTCGGGCTGCCCGAGGCGATCGTCGGCCGCCAGCCGTTC
CCGGGCCCGGGGCTGGGCATCCGGATCGTCGGCGAGGTCACCAAGGCGCGGCTGGACCTGCTGCGCGAGGCCGACGCCAT
CGCCCGCGAGGAGCTGACCGCGGCCGGGCTGGACACCGAGATCTGGCAGTGCCCGGTGGTGCTGCTGGCCGACGTGCGCT
CGGTCGGCGTGCAGGGCGACGGCCGGACCTACGGCCACCCGATCGTGCTGCGTCCGGTCTCCAGCGAGGACGCCATGACC
GCCGACTGGTCGCGCCTGCCGTACGAGGTGCTGGCGCGGATCTCCACGCGGATCACCAACGAGGTCGCCGAGGTCAACCG
GGTGGTGCTGGACGTCACCAGCAAGCCGCCGGGGACGATCGAGTGGGAGTAG

Protein sequence :
MEQPADTVLVIDFGAQYAQLIARRVREAHVYSEIVPHTATVAEILAKKPKAVILSGGPSSVYADGAPNVGAELFRAGVPT
LGICYGFQAMARALGGVVEQTGGREYGRTSLEVTDTESTLFQGSHSEQPVWMSHGDAVVAAPEGFRVTGTTAKTPVAAFE
DDEKRLYGVQHHPEVLHSQFGQLLLENFLYKGAGIAPDWTTGNIVEEQVASIREQVGTKRAICGLSGGVDSAVAAAIVQK
AVGEQLTCVFVDHGLLRKGEAEQVEKDFVAATGVQLKVVDAEQRFLSALAGVSDPEEKRKIIGREFIRVFEQAEREIVEQ
SADAGEPVRFLVQGTLYPDVVESGGGTGAANIKSHHNVGGLPDDLQFELIEPLRKLFKDEVRQVGRELGLPEAIVGRQPF
PGPGLGIRIVGEVTKARLDLLREADAIAREELTAAGLDTEIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMT
ADWSRLPYEVLARISTRITNEVAEVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-179 71
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-139 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-139 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-139 52