Gene Information

Name : Afer_0460 (Afer_0460)
Accession : YP_003109101.1
Strain : Acidimicrobium ferrooxidans DSM 10331
Genome accession: NC_013124
Putative virulence/resistance : Unknown
Product : GMP synthase, large subunit
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 457915 - 459468 bp
Length : 1554 bp
Strand : +
Note : KEGG: fre:Franean1_5989 bifunctional GMP synthase/glutamine amidotransferase protein; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase domain protein; ExsB family protein; glutamine amidotransferase class-I

DNA sequence :
GTGCGCCACGCCGACGAGCAGGTCGTCCTTGTCGTCGACTTCGGCGCGCAGTACGCGCAGCTGATCGCACGGCGGGTGCG
CGAACTCCACGTGTACTCGGAGGTCGTCCCGGCTCGGGACGCACTGGCGTTCGTCCGCTCGCGGCGGCCGGCGGCGGTGA
TCCTCTCGGGTGGTCCGGCGTCCGTATACGCCCCCGGTGCGCCGGGGCTCGCGCCCGAGGTGCTCGAGGCGAACGTGCCC
ATCCTCGGGATCTGCTACGGCGCTCAGCTGATGGCCCAGCAGCTTGGCGGCGTCGTCGAGCACGGAGGTTCGGGTGAGTA
CGGCAGAACGGTGATCGAGCGCACCGACGAGCGTGCGCACCTGCTCCCGCCGCTCCGTGGCGAGGCGCCTGAGACGGTGT
GGATGAGTCACGCCGACGCGATCGTTGCCCCGCCCGAGGGCGCGCGGGTGGTCGCGAGCTCGGCCGGGGCACCGGTCGCG
GCCTTCGAGGATCCCGCGAGGCGGCGCTTCGGTGTGCAGTGGCATCCCGAGGTCTCGCACACCCCAGGTGGCATGGAGCT
CCTCGGACGGTTCCTGTTCGACGTGGTGGGGCTCGAGCCGCGCTGGACGAGTTTTTCGATCATCGAGCAGGCGATCGCAG
AGGTCCGGAGCACGGTCGGCGATGGTCGGGCGATCTGTGCGCTCTCGGGTGGGGTGGATTCGACCGTGGCCGCGGCGCTC
ACCGCCGAGGCGATCGGCGACCGGCTCACCTGCGTCTTCGTCGACACGGGCCTCCTGCGCTCGGGCGAGGCGGAGCAGGT
CGAACATCTGTTCCGTTCCCAGTTCGACATCGAGCTGATCGTGGTGGACGCGGCCGATCGCTTCTTCGACGCCTTGGCGG
GCGTGACCGACCCCGAGGCCAAGCGCAAGATCATCGGCGAACTCTTCATCCGCATCTTCGAAGAAACGGCGGCCTCGAAG
ACCAACGCGACCCACCTCGTCCAGGGCACGCTCTATCCGGACATCGTCGAGTCCGGTAGCGATGGCTCGGCGACCATCAA
GTCGCACCACAACGTCGGCGGCCTCCCGGACGACGTCGCGTTCACGATCGTCGAGCCACTGCGACGCCTGTTCAAGGACG
AGGTCCGTCGCATCGGCGTCGAGCTCGGTATCCCCGAGTCGTTCGTGTGGCGCCAACCATTCCCCGGTCCGGGGATCGCG
GTTCGAGTGCTCGGCGAGGTGACCGCAGAGCGGGTCGAGACGGTTCGCCGTGCGGATCGCATCGTCCAAGACGAGCTCGA
CGAGGCTGGGCTCTCGCGCTCGCTATGGCAGGCCTTCGCGGTCCTGGCCCCTGGGCTCCGGTCGGTCGGCGTCTCGGGGG
ACGCGCGTACCTACGACGCCCCGGTCATCGTGAGGGCGGTCGAGTCCGAGGACGCCATGACCGCAGATTGGGCACGGCTG
CCATGGGAGGTGCTCGATCGCATCTCGCGGCGGATCGTCAACGAGGTCCCGGGCGTCAATCGCGTCGTCTATGACGTGAC
CTCCAAGCCGCCAGGCACCATCGAGTGGGAGTGA

Protein sequence :
MRHADEQVVLVVDFGAQYAQLIARRVRELHVYSEVVPARDALAFVRSRRPAAVILSGGPASVYAPGAPGLAPEVLEANVP
ILGICYGAQLMAQQLGGVVEHGGSGEYGRTVIERTDERAHLLPPLRGEAPETVWMSHADAIVAPPEGARVVASSAGAPVA
AFEDPARRRFGVQWHPEVSHTPGGMELLGRFLFDVVGLEPRWTSFSIIEQAIAEVRSTVGDGRAICALSGGVDSTVAAAL
TAEAIGDRLTCVFVDTGLLRSGEAEQVEHLFRSQFDIELIVVDAADRFFDALAGVTDPEAKRKIIGELFIRIFEETAASK
TNATHLVQGTLYPDIVESGSDGSATIKSHHNVGGLPDDVAFTIVEPLRRLFKDEVRRIGVELGIPESFVWRQPFPGPGIA
VRVLGEVTAERVETVRRADRIVQDELDEAGLSRSLWQAFAVLAPGLRSVGVSGDARTYDAPVIVRAVESEDAMTADWARL
PWEVLDRISRRIVNEVPGVNRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-138 60
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-131 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-131 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-131 53