Gene Information

Name : Afer_2009 (Afer_2009)
Accession : YP_003110584.1
Strain : Acidimicrobium ferrooxidans DSM 10331
Genome accession: NC_013124
Putative virulence/resistance : Resistance
Product : pyridine nucleotide-disulfide oxidoreductase dimerization subunit
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 2128009 - 2129424 bp
Length : 1416 bp
Strand : +
Note : PFAM: pyridine nucleotide-disulphide oxidoreductase dimerization region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: ace:Acel_0690 mercuric reductase

DNA sequence :
ATGGTCATGAGCACCCTTCACGCATCCGCTCCCTGGGATCTCGGCATCATCGGCTCTGGCTCAGCCGCCTTTGCCGCCGC
GCTCGAGGCTCGCGCACGCGGCGCCTCGGTCGTCCTGATCGAACGCGATGCGCTGGGCGGCACCTGCGTGAACGTGGGTT
GCGTGCCCTCGAAGGCACTGCTCGTCGCGGCACACCGCCGAAGCCTCGCCGCATCGGCGTACCCGGGCCTCGGAGCCGAG
ACACTCCCCATCGACCACGACGAACTCGCTGCCGGGGTTCGCGGCGTGGTTTCGAGCCTCGTCAAGCGGAAGTACCGCGA
TCTCGCTGAGCGGATGGGGATCGACGTACGCTACGGTACTGCGCGCTTCGTGTCCGACGAGACGGTGAGCGTCGGCGGTG
ACGAGCTCACCGCGCGCCGCTGGATCATCGCAACCGGTGCCCATGCGGTACTGCCATCGGTCGACGGTCTCGACCCAGCG
GAGCTCTGGACCTCCACCGACGCTCTCACGGCGCTCGAGATTCCCGCTCGCGTCGCGATCATCGGCGCCGGCTCGATCGG
TCTCGAACTCGCGACCGCCTACAGCGGGCTCGGAGCCCGGGTCCACCTGATCGAGAGCACTCCCCAGGCTGTCGCGAGTG
CGCCGCTCGAACTGACAGGAGCCCTGGTCGAGCACCTCCGCGCATCCGGTGTCGCCGTGGCGCTCACGACCACGGTCGGT
TCTGCACAGGCGACGACCTCAGGGTGGCTCCTCCAGCTGCAAGGACCAGAAGGTGCGACGCAGGTGGAGGTCGATCGGGT
GATCGCGGCCGTGGGTCGGCGCCCCACCACCGAGAATCTGGGGCTGGAGACGGTCGGCGTCGAACTCGGGGCCCGCGGGG
AAGTCGTCGTCGACGCCACCATGCGTACGTCGAATCGAGGCATCTGGGCGGCCGGCGACGTGACCGGCGGACCCCAGTAC
GTCTACGTCGCTGCCGCCCAGGGCGCGCTCGCAGCCCGCAACGCCCTCTCCGACGGTGACGAGCACTTCGACGACCGCGC
GATTCCCGCCGTCGTCTTCACCGATCCGCCCCTGGCCCAGGTCGGTCTGACGCTCGACGAGGCACAACACCAGGGCTACG
ACGCCGAGTCGACCACCTTCTCGTTCGCCGATCTCCCACGTGCAATCGTCGAGCACGCGACCGAGGGCCTGGCCGTCATG
GTCGCAGAACGCACGAGTGGGCGCCTCCTCGGCGTGCACCTCTGGGGCGTGAACGCAGCCGAAGTCATCCAGAGCGCCGT
GCTCGCACTCCGCACCAATCTCACGATCAGCGACCTCGCGACAACGTGGGCACCCTACCTCACGGCCTCCGAGGCGCTTC
GGCTCGCAGCACAGAGCTTCACAACGGACGTCGCGAACCTGTCCTGCTGCGCCTAG

Protein sequence :
MVMSTLHASAPWDLGIIGSGSAAFAAALEARARGASVVLIERDALGGTCVNVGCVPSKALLVAAHRRSLAASAYPGLGAE
TLPIDHDELAAGVRGVVSSLVKRKYRDLAERMGIDVRYGTARFVSDETVSVGGDELTARRWIIATGAHAVLPSVDGLDPA
ELWTSTDALTALEIPARVAIIGAGSIGLELATAYSGLGARVHLIESTPQAVASAPLELTGALVEHLRASGVAVALTTTVG
SAQATTSGWLLQLQGPEGATQVEVDRVIAAVGRRPTTENLGLETVGVELGARGEVVVDATMRTSNRGIWAAGDVTGGPQY
VYVAAAQGALAARNALSDGDEHFDDRAIPAVVFTDPPLAQVGLTLDEAQHQGYDAESTTFSFADLPRAIVEHATEGLAVM
VAERTSGRLLGVHLWGVNAAEVIQSAVLALRTNLTISDLATTWAPYLTASEALRLAAQSFTTDVANLSCCA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 1e-64 42
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 4e-63 41
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-65 41
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-65 41
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 3e-63 41
merA AFG30120.1 MerA Not tested PAGI-2 Protein 3e-63 41
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 5e-65 41
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-65 41
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 7e-64 41
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 7e-64 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Afer_2009 YP_003110584.1 pyridine nucleotide-disulfide oxidoreductase dimerization subunit BAC0650 Protein 5e-63 42
Afer_2009 YP_003110584.1 pyridine nucleotide-disulfide oxidoreductase dimerization subunit BAC0652 Protein 2e-65 41
Afer_2009 YP_003110584.1 pyridine nucleotide-disulfide oxidoreductase dimerization subunit BAC0653 Protein 5e-65 41