Gene Information

Name : Afer_1964 (Afer_1964)
Accession : YP_003110541.1
Strain : Acidimicrobium ferrooxidans DSM 10331
Genome accession: NC_013124
Putative virulence/resistance : Unknown
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2060927 - 2063413 bp
Length : 2487 bp
Strand : +
Note : KEGG: nfa:nfa54020 Clp protease ATP- binding subunit; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATP

DNA sequence :
ATGAGAACCGATCACTTCACCCACAAGCTCCAAGAGGCGCTGCAGGATGCGAAGCGCCTCGCCACCGAGCGCCAGAACCC
CGAGGTCACCCCGCAGCACCTCGCGCTCGCCCTGCTCGGCCAACCCGACGGGATGGCGCTCGCCGTCCTCTCGCGAGCCG
GGATCGCTCCCGCCAGCGTGCGCAACCAGCTCCTCGAGGCCCTCGAGCGCCTACCACGCGCCTACGGCCAAGCGGCCGAA
CCGGCAGGATCGGCGGCGCTCGCACGGGTGCTCGAGCGCGCCGAGCAGCTGCGCGGTGAGTACGGCGACGACTACCTCTC
CGTCGAGCACGTCCTGCTCGCCATGGCGGCCGTGCTCAAGGTCGACGAGGCGACGCTGCGCCAGGCGATCGACGCCGTGC
GTGGCGGACGCCGTGTGACCTCGGCCGACCCCGAGGACACCCTAGAAGCGCTCACCAAGTACGGGCGCGACCTCACCGAG
GCTGCACGCGCAGGCTCCATCGACCCCGTGATCGGCCGTGACGAAGAGATCCGTCGGGTCATCCAGATCCTCTCGCGTCG
GCAGAAGAACAACCCGGTCCTCATCGGCGAACCCGGCGTCGGCAAGACCGCGATCGTCGAGGGGCTCGCACGCCGGATCG
TCGAAGGTGACGTGCCCGAAGGCCTGCGCGGCAAGCGGATCATCGCGCTCGATCTCGGCTCCATGGTCGCAGGAGCGCAG
TACCGCGGTCAGTTCGAGGAACGCCTCAAGAGCGTGCTCGACGCCATTCGCCAGAGCGAAGGCGAGGTCATCACCTTCAT
CGACGAGCTCCACACCGTGGTCGGTGCGGGTGCGGCCGAGGGATCGCTCGACGCCTCCAACATGCTCAAGCCCATGCTCG
CGCGCGGCGAGCTGCGCATGATCGGCGCGACCACCCTCGACGAGTATCGCAAGCACATCGAGTCCGACGCCGCACTCGAG
CGACGCTTCGCCAAGGTCATGGTCGACCAGCCCAGCGTCGAGGAGACGGTCGCGATCCTGCGCGGCTTGAAGGAGCGCTA
CGAGGTGCACCACGGCGTGCGGATCCAAGACGCCGCCCTGGTCGCTGCCGCGGTCCTGTCGGATCGCTACATCACCGATC
GCTTCTTGCCCGACAAGGCGATCGACCTCGTGGACGAGGCCATGGCCCGACTGCGCATGGAGATCGACTCGCGACCCGAG
GAGATCGACTCCGTCGAGCGCCGTCTGCGCCAGCTCGAGATCGAGCGCATCTCACTCGCGACCGAGACCGACCGCGCCTC
ACGCGAGCGCCTCACCCGCCTCGACCAGGACATCGAGGCCACGAAGCTCGAGCTCAGTGAGCTGACCCGCCAGTGGCAAG
CCGAACGGGAAGCGATCGACGTCATCCGCCAGCGCAAGGAGCACCTCGAGGAGCTGCGTGCCCAGTCGGAAGCCTACGAG
CGCCAAGGCATGCTGGACCGCGCCGCCGAGCTGCGCTATGGCGAGATCCCTCGCCTCGAGCGCGAGATCGAGGAGGCGAC
CGAAGAACTCTCGAAGCGCCAGGGTGGCCGGCGCATGCTCAAGGAGGAGGTCGACCCCGAGGACATCGCCGAGGTGGTCG
CGGCCGCGACCGGCATCCCGGTGACCAAGCTCCTCGAGAGCGAGACCGAGAAGCTGCTCCACATCGAAGACGCACTGCGT
GCGCGGGTGGTGGGTCAAGACGAGGCGATCGACGCGGTGGCGAACGCCATCCGGCGCAGCCGTGCCGGCATCGCCGATCG
GAACCGCCCCATCGGCTCCTTCCTCTTCCTCGGCCCGACGGGCGTCGGCAAGACCGAGACCGCCAAGGCGCTCGCGGAGT
ACCTCTTCGACGACGAGCGAGCCATGATCCGCATCGACATGAGCGAGTACCAGGAGCGTCACAGCGTCTCGCGCCTCGTC
GGTGCGCCCCCTGGCTACGTCGGCTACGACGAGGGCGGACAGCTCACCGAGGCGGTGCGGCGCCGTCCCTACGCGGTGGT
CCTCTTCGACGAGATCGAGAAGGCGCACGCCGACGTGTTCAACGTGTTCCTCCAGATCCTCGACGACGGCCGCCTCACCG
ACGGTCAGGGGCGGGTGGTGAACTTCACGAACACCATCCTCATCATGACCTCGAACCTCGCCGACGATCCGCGGCGCTTC
TTCAAGCCCGAGTTCGTGAACCGCATCGACGAGATCGTGCGCTTCCACGAGCTCACCTCGGACCAGATCCGCGCCATCGT
CGACCGCCAGATGGCCCAACTCGCCGGTCGGCTCGCCGAGCGCTCACTCGGTCTCGAGGTCACCGACGCCGCGGCGGCCC
TGCTGGCCGAGCGCGGCTGGGATCCGGCCTTCGGTGCTCGACCCCTGCGTCGAGCCATCCAACGCCTCGTCGGCGACCCG
CTGGCCAGAGCGCTTCTCGAAGGGCGCTACGGCGAGGGAGACACGGTCGTGGTCGACGCGGCCGACGGCGCCATCGTGCT
GCGCTGA

Protein sequence :
MRTDHFTHKLQEALQDAKRLATERQNPEVTPQHLALALLGQPDGMALAVLSRAGIAPASVRNQLLEALERLPRAYGQAAE
PAGSAALARVLERAEQLRGEYGDDYLSVEHVLLAMAAVLKVDEATLRQAIDAVRGGRRVTSADPEDTLEALTKYGRDLTE
AARAGSIDPVIGRDEEIRRVIQILSRRQKNNPVLIGEPGVGKTAIVEGLARRIVEGDVPEGLRGKRIIALDLGSMVAGAQ
YRGQFEERLKSVLDAIRQSEGEVITFIDELHTVVGAGAAEGSLDASNMLKPMLARGELRMIGATTLDEYRKHIESDAALE
RRFAKVMVDQPSVEETVAILRGLKERYEVHHGVRIQDAALVAAAVLSDRYITDRFLPDKAIDLVDEAMARLRMEIDSRPE
EIDSVERRLRQLEIERISLATETDRASRERLTRLDQDIEATKLELSELTRQWQAEREAIDVIRQRKEHLEELRAQSEAYE
RQGMLDRAAELRYGEIPRLEREIEEATEELSKRQGGRRMLKEEVDPEDIAEVVAAATGIPVTKLLESETEKLLHIEDALR
ARVVGQDEAIDAVANAIRRSRAGIADRNRPIGSFLFLGPTGVGKTETAKALAEYLFDDERAMIRIDMSEYQERHSVSRLV
GAPPGYVGYDEGGQLTEAVRRRPYAVVLFDEIEKAHADVFNVFLQILDDGRLTDGQGRVVNFTNTILIMTSNLADDPRRF
FKPEFVNRIDEIVRFHELTSDQIRAIVDRQMAQLAGRLAERSLGLEVTDAAAALLAERGWDPAFGARPLRRAIQRLVGDP
LARALLEGRYGEGDTVVVDAADGAIVLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-93 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 3e-98 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-98 41