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Name : entE (BMI_II15) Accession : YP_003104819.1 Strain : Genome accession: NC_013118 Putative virulence/resistance : Virulence Product : enterobactin synthase subunit E Function : - COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism COG ID : COG1021 EC number : 2.7.7.58 Position : 12098 - 13939 bp Length : 1842 bp Strand : - Note : bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate DNA sequence : TTGTGCGCCTCTTTGCCGGGGCGGGGATCGTGGAAGCCTCCAGCCCGGATTCCGAATGGGCCGAAGTACAGACCAAGCTT GGCACCATGCTGCGTGCCTGCGGCCTTTCGGCCTGAAACAGAGCCTCTCCATGTCTTTGTTTCTACGCATTATCCGACGC AGAGCCGCTTCGCATTGCGGGCTCGAAAACTGCACTCGTTTTTATTTCAAGCAGAACAAGTCATGACCATCGAATTTACC CATTGGCCACCGGCACGCGAACGCCTCTATCGCGAAAAGGGCTACTGGATCGACAAACCCCTCACCCGCGCACTGGAAGA ACAGGCCGCCATGCGGCCCGATGCGCCCGCTATCCTCTGCGGCGAGCGGCGTTTCACCTATGCCGAACTCGACCGTCTGT CTTCCAACCTGGCCTCCCGGCTTGCGGCAGCCGGCATAGGCAAAGGCGACACGGCACTGGTGCAACTGCCCAATATCGCC GAATTCTACATCGTGTTCTTCGCACTCATGAAAGCGGGCATCGCGCCCGTCAATGCGCTTTTCAGCCATCGCAAGCTGGA GCTTGGCGCCTATGCCAGCCAGATCGAACCACGGCTGCTGATCGGCTCACGCCAGCATGAACTCTTCATGGATGACGCCT TTGCCCGCGACCTTGGCAAAAATCTTTCCGCACCGCTGCTAACACTTTTTGCAGGCGAGGCCGACCCTGCGTCGAGCCTC GACCACTGGATCGCCACGCCTGCGGACAAAGCCGTTCCCTTCTCGCCAACCGGCGCTGGCGAAGTCGCCTTTTTCCAGCT TTCCGGCGGCAGCACCGGCACGCCGAAACTCATCCCGCGCACGCATAATGATTATGATTACAGCGTGCGCGCCAGCGCGG AAATCTGCGCGCTGACACCGCAGACCCGTTTTCTCTGCGCCCTGCCCACCGCGCATAATTATCCAATGAGTTCGCCCGGC GCGCTCGGCGTTTTCCATGCGGGCGGCTGTGTCGTCATGGCCCCCAACCCGGAACCGCTCAACTGCTTCTCCATCATCGA ACGTCATGGCGTAAACATGGTGGCACTGGTGCCTCCGGCAGTGGCGCTCTGGCTACAGGCAGCCCCCGATCATCTGGCAG CACTCAGCTCGCTGAAACTCGTGCAGGTGGGTGGCGCAAGCTTTGCGGAGGCGCTTGCCCGGCAGGTGCCACAGGTTCTG GGCTGCAAGCTGCAACAGGTCTTCGGCATGGCCGAGGGGCTGGTCAACTATACCCGCCTTGACGACCCGGACGAGATCGT CTTCACCACCCAGGGCCGTCCGATCAGCCCGGACGATGAAATCAGGATCGTCGATGAGGATGGCGAACCCGTGGCCGAAG GCCAGCCAGGAATGCTGGCCACGCGCGGGCCTTACACGTTCTGCGGCTATTATCGCAGCCCCGAACATAATGCGCAGGTC TTCGACAGTGAAGGCTTTTATTATTCGGGCGACGTGGTCCAGCGCACGCCGGAAGGCTATCTGCGCGTCGTGGGCCGCGT GAAGGACCAGATTAATCGCGGCGGCGAGAAAGTTGCCGCCGAGGAGATTGAAAACCTGATCCTCCTCCATCCCGATGTGA CGCACGCCGCACTTGTCGCCATGCAGGATGAATTGCTGGGCGAGAAAAGCTGCGCTTTCATCGTCTCGCGCAATCCCGAT CTCAAGCCGCCTGTTCTGCGGCGTCACCTGCTGGCGCTGGGCGTTGCCGAATACAAGCTTCCAGACCGCATCAGGCTCAT TGAAACCATGCCGCTCACCGCAGTTGGCAAGATCGACAAAAAGCATCTGCGCAAGCTTTCAAGCCCATCCTCCCCCGGTT AG Protein sequence : MCASLPGRGSWKPPARIPNGPKYRPSLAPCCVPAAFRPETEPLHVFVSTHYPTQSRFALRARKLHSFLFQAEQVMTIEFT HWPPARERLYREKGYWIDKPLTRALEEQAAMRPDAPAILCGERRFTYAELDRLSSNLASRLAAAGIGKGDTALVQLPNIA EFYIVFFALMKAGIAPVNALFSHRKLELGAYASQIEPRLLIGSRQHELFMDDAFARDLGKNLSAPLLTLFAGEADPASSL DHWIATPADKAVPFSPTGAGEVAFFQLSGGSTGTPKLIPRTHNDYDYSVRASAEICALTPQTRFLCALPTAHNYPMSSPG ALGVFHAGGCVVMAPNPEPLNCFSIIERHGVNMVALVPPAVALWLQAAPDHLAALSSLKLVQVGGASFAEALARQVPQVL GCKLQQVFGMAEGLVNYTRLDDPDEIVFTTQGRPISPDDEIRIVDEDGEPVAEGQPGMLATRGPYTFCGYYRSPEHNAQV FDSEGFYYSGDVVQRTPEGYLRVVGRVKDQINRGGEKVAAEEIENLILLHPDVTHAALVAMQDELLGEKSCAFIVSRNPD LKPPVLRRHLLALGVAEYKLPDRIRLIETMPLTAVGKIDKKHLRKLSSPSSPG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| irp5 | YP_001006819.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 5e-86 | 44 |
| ybtE | AAA93464.1 | yersiniabactin 2,3-dihydoxybenzoate-AMP ligase | Virulence | HPI | Protein | 6e-86 | 44 |
| irp5 | CAA73130.1 | Irp5 protein | Virulence | HPI | Protein | 3e-86 | 44 |
| irp5 | YP_002346898.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 8e-86 | 44 |
| ybtE | NP_669710.1 | salicyl-AMP ligase | Virulence | HPI | Protein | 8e-86 | 44 |
| ybtE | NP_993003.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 8e-86 | 44 |
| ybtE | YP_070120.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 8e-86 | 44 |
| ybtE | CAA21394.1 | - | Virulence | HPI | Protein | 8e-86 | 44 |
| ybtE | YP_853079.1 | yersiniabactin siderophore biosynthetic protein | Virulence | PAI IV APEC-O1 | Protein | 8e-86 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| entE | YP_003104819.1 | enterobactin synthase subunit E | VFG0932 | Protein | 6e-143 | 58 |
| entE | YP_003104819.1 | enterobactin synthase subunit E | VFG0168 | Protein | 6e-107 | 47 |
| entE | YP_003104819.1 | enterobactin synthase subunit E | VFG1817 | Protein | 9e-88 | 41 |
