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Name : lysS (Amir_0906) Accession : YP_003098712.1 Strain : Actinosynnema mirum DSM 43827 Genome accession: NC_013093 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 995843 - 999127 bp Length : 3285 bp Strand : + Note : catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : GTGGCGGTTGCCGGGTGGAAGTGGCGGGCGGCGGGGGTCGTCGCCACGGTCGTGCAGGTCTCCGCGCTGGCCTCCCTGGT GCTGCTGCTGTGGGCCGAGGGCACGACCCTCGGCGACGTCATCTTCTTCTCCGGCTACGCCCTCGGCCTGCCGGTCGAGG CGAACCTGTTCATCGTCCTGGTCCTGGTGGTCCTCGGCGCGGCGCTGCGCGCCCGCAAGCGCGCGGCCCTGTGGGCCCTG CTGCTCACCGAGGCGCTCGGCCTCGCCTGGAACCTGGCCGTGCTGCTCCTGCTCGCCGTCGCCCCCGACGTGCCGGCGTC GGGGGAGCAGGTGGACTGGCGGCGCGCGCTGGGCTTCCTGGGCGGCGGCGCCCTCACCGCCCTGGTCATCATCGCCTTCC TGCTGGCGATCCGGGAGGCGTTCCCCGCCGAGCTGGCCCCCGGCGCCTGGCGCAAGGCGCTGGCCGCGTTCATCGTCGGC CTCGCCGCCGCCGCCACCGCCGGGTTCCTGCTCACCGAGGTCTTCCCCGGCTCCCTCCGCGACCAGGGCGAGATGCTGGT CTGGGCGGCCAACCAGGTCTCCGGCGAGGTGGTGCCGCTGCGCCGCGCCCTGTCCGGCGAGGGCCCGGCCTGGCTGAGCG TGCTGCTCGGCGTCACCGGCACGCTCGTCGCGATCTTCGCCCTGTACCTGTTCTTCCGGGGCGAGCGCTCCAGCCGGTGG ATCAACGTCGACGAGGAGCTCACCCTGCGCCGCCTGCTGGCCGCCCACGGCGAGCCGGACTCGCTCGGCTACTTCGCCAC CCGCCGCGACAAGAGCGCCGTGCTCTCCCCGGACGGCCGCGCCGCGCTGACCTACCGGGTGCTCGCGGGCACCACCCTGG CCAGCGGCGACCCGGTCGGCGACGAGGACTCCTGGCGGCAGGCGGTGCGGGCCTGGCTCGACGAGGCCCGCCGGTACGGC TGGCGCGCGGGCGTCCTCGGGGCCAGCGAGCGCGGCGCCCGCGCCTACGCGGCCGAGGGCCTCAAGGCGCTGGAGATCGG CGACGAGGCCGTGCTGGACGTGCGCGAGTTCAGCCTCGCCGGACCGGAGCGGCGCGCGGTCCGGCAGGCGGTCAGCCGAG TGGAGCGCGCCGGGTACACCGCGCGGGTGCGCAGGCACGCCGAGATCCCCGCCGACGAGATGGCCGGGCTGCTCGACCTG GCCCAGCGGTGGCGCGGCGCGCAGACCGAGCGCGGCTTCTCCATGGCGCTCGGCAGGCTCGGCGACGAGTCCGACGGCCG GTGCGCGATGGTCGAGGCCTACGACGCGGACGGCGCGCTGCGCGGGCTGCTCTCGTTCGTGCCGTGGGGCAGGCGCGGGC TGTCCCTCGACCTGATGCGGCGCGACCGGACCGCCGAGAACGGGCTCAACGAGTTCATGGTCGCCGAGCTGGTCGCCGCC GCCGGACGGCTGGGCGTGCAGCGGGTGTCGCTGAACTTCGCCATGTTCCGCGCGGTGTTCGAGGAGGGCGAGAAGCTCGG GGCCGGACCGGTGCTGCGGGCCTGGCGCGGCGTCCTCGGCCTGGCCTCCCGGTTCCTGCAGCTGGAGTCCCTGTACCGCT CCAACGCCAAGTACGGCCCCGACTGGCAGCCCCGCTACCTCTGCTACTCGGGCGTGCGGAGCCTGCCGAGGGTGAGCGTC GCGGCGGGCGTCGCCGAGGGCTTCGTGCCGAACCTGCGCTCCCTGCTCAAGCGCGGCTCCCGCCGCCGGGGCCTGGACGG GGCCACCACGTCCGGCCGCTGGTTCGCCGACGCCGTCCGCGAGATCGAGGCCACCCGCCCCGAACCGGCCCGCGCCCGCC GCCCCGAGCAGGTCAGGGTCCGCATGGCCAAGCTCGACCTGCTGCGCGCCGCGGGCCGCGACCCGTACCCCGTCGGCTAC GACCGCGACTGCCCCGTCGCCGAGGTCGAGTCCCGGTTCGGGCAGGTCGTCGCGATCACCGGCCGGGTCGTGGCGCTGCG CGAGCTGGGCGGCCTGTGCTTCGCCCGCGTCCGCGACTGGACCGGCGAGGTGCAGGTCATGCTGGACGCCGCCACCACCG AGGACCTGCACCTGTGGAAGTCCGGCGTCGACCTGGGCGACCACGTCGGCGCGCGCGGCGAGGTCGTGCGCTCCCGGCGC GGCGAGCTGTCCGTGCTGGTCGCCGACTGGGCGATCACCGCCAAGTGCCTGCACCCGCTGCCCGACCGCCGCGCGGGCCT GGCCGACCCGGAGGCGCGGGTCCGCAAGCGCTACCTGGACCTGGCGGTCAACCCCGACTCGGCCGCGATGCTGCGCACCC GCAGCGCCGTCGTGCGCGCCGTCCGGGACTTCCTGCACGACCGGGGCTACCTGGAGGTCGAGACCCCGATGCTCCAGACC GTGCACGGCGGGGCCAACGCGCGGCCGTTCGTCACCCACATCAACGCCTACGACACCCGCATGTACCTGCGGATCGCGCC CGAGCTGTACCTGAAGCGGTTGTGCGTGGCGGGCGTGGACCGGGTGTTCGAGCTGAACCGGAACTTCCGCAACGAGGGCG CCGACGCCACCCACAACCCGGAGTTCACCATGCTGGAGGCGTACCAGGCGTACGCCGACTACCGGGTGATGCTGGACCTG GTGCGGGAGCTGGTGCAGCACGCCGCGGTGGCCGCGCACGGCAGGCAGGTCGCGGTCCGCGACGGCGCGGAGGTCGACAT CTCGGGTGAGTGGCCGGTGGTGCCGGTGCACGCGGCCGTGTCCACCGCGCTCGGCGTGCAGGTCGGCCCGGACCTGCCGC TGGACGAGCTGCGCGCCGCGCTGGTCGCCGGGGGCGTGCCGCTGCCGGAGGACCTGGAGGCCGACCACGGGACGCTGGTG CTGCGCGCCTACGACCACCTCGTGGAGCCCGCCACGACCGCCCCGACCTTCTACACCGACTTCCCCACCTCGGTGTCCCC GCTGACCAGGGAGCACCGCGCCGACCCCCGGCTGGCCGAGCGCTGGGACCTGGTCGCGTTCGGCGCGGAGGTCGGCACCG CCTACTCCGAGCTGACCGACCCGGTCGAGCAGCGCCGCAGGCTGGAGGCCCAGTCGCTCAAGGCCGCCAGCGGCGACGTC GAGGCGATGGAGCTGGACGAGGACTTCCTGGCCGCGCTGGAGCACGGCATGGCCCCCACCGGCGGCCTTGGCCTGGGCGT GGACCGCCTGCTGATGATGCTCACCGGGGCGAGCATCCGGCAGACGGTCCTGTTCCCGTTCGTCCGCCCCGGGCCGAAGT CCTGA Protein sequence : MAVAGWKWRAAGVVATVVQVSALASLVLLLWAEGTTLGDVIFFSGYALGLPVEANLFIVLVLVVLGAALRARKRAALWAL LLTEALGLAWNLAVLLLLAVAPDVPASGEQVDWRRALGFLGGGALTALVIIAFLLAIREAFPAELAPGAWRKALAAFIVG LAAAATAGFLLTEVFPGSLRDQGEMLVWAANQVSGEVVPLRRALSGEGPAWLSVLLGVTGTLVAIFALYLFFRGERSSRW INVDEELTLRRLLAAHGEPDSLGYFATRRDKSAVLSPDGRAALTYRVLAGTTLASGDPVGDEDSWRQAVRAWLDEARRYG WRAGVLGASERGARAYAAEGLKALEIGDEAVLDVREFSLAGPERRAVRQAVSRVERAGYTARVRRHAEIPADEMAGLLDL AQRWRGAQTERGFSMALGRLGDESDGRCAMVEAYDADGALRGLLSFVPWGRRGLSLDLMRRDRTAENGLNEFMVAELVAA AGRLGVQRVSLNFAMFRAVFEEGEKLGAGPVLRAWRGVLGLASRFLQLESLYRSNAKYGPDWQPRYLCYSGVRSLPRVSV AAGVAEGFVPNLRSLLKRGSRRRGLDGATTSGRWFADAVREIEATRPEPARARRPEQVRVRMAKLDLLRAAGRDPYPVGY DRDCPVAEVESRFGQVVAITGRVVALRELGGLCFARVRDWTGEVQVMLDAATTEDLHLWKSGVDLGDHVGARGEVVRSRR GELSVLVADWAITAKCLHPLPDRRAGLADPEARVRKRYLDLAVNPDSAAMLRTRSAVVRAVRDFLHDRGYLEVETPMLQT VHGGANARPFVTHINAYDTRMYLRIAPELYLKRLCVAGVDRVFELNRNFRNEGADATHNPEFTMLEAYQAYADYRVMLDL VRELVQHAAVAAHGRQVAVRDGAEVDISGEWPVVPVHAAVSTALGVQVGPDLPLDELRAALVAGGVPLPEDLEADHGTLV LRAYDHLVEPATTAPTFYTDFPTSVSPLTREHRADPRLAERWDLVAFGAEVGTAYSELTDPVEQRRRLEAQSLKAASGDV EAMELDEDFLAALEHGMAPTGGLGLGVDRLLMMLTGASIRQTVLFPFVRPGPKS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysX | YP_003784331.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-161 | 45 |
| lysS1 | YP_005686365.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-161 | 45 |
| lysS1 | YP_005682181.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 3e-161 | 45 |
| lysS1 | YP_005684273.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-161 | 45 |
