Gene Information

Name : Amir_0718 (Amir_0718)
Accession : YP_003098527.1
Strain : Actinosynnema mirum DSM 43827
Genome accession: NC_013093
Putative virulence/resistance : Unknown
Product : inosine 5-monophosphate dehydrogenase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0516
EC number : 1.1.1.37
Position : 794926 - 796359 bp
Length : 1434 bp
Strand : -
Note : catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate

DNA sequence :
GTGCGATTCATCGAAGGGCGCCAGCCCGCCAACGACCTGACCTACGACGACGTCTTCCTGGTCCCCGGCCGCTCCGCCGT
GGACTCCCGGTTCGGGGTCGACCTCTCCACCTCCGACGGCACGGGCGCCACGATCCCCGTGGTCGTGGCCAACATGACCG
CCGTCGCGGGCCGCCGCATGGCGGAGACGATGGCCAGGCGCGGCGGCCTGGTCGTGCTGCCCCAGGACGTGGCCCCCGAG
GCGGTGGCCGAGATCGTGTCCTGGGTCAAGGAGCGGCACCCCGTGTGGGACACGCCGCTGGTCCTGTCCCCGAACGACTC
AGTCGCGGACGCGTTCAACCTGCTGCACAAGCGCGCCCACGGCACCGTCGTGGTGGTCGGCCAGGACGGGCGCCCGGTGG
GCACCGTGGACGAGCACGCGCTGGGCGGCGTGGACCGGTTCACCCGGCTGAGCGAGGTGGCCGACCACGACGTGGTCGTG
CTGCCGCTGGACACCGCGCCGCGCGAGGTCTTCGAGCGGCTGGGCGCGCACCGGGCCGCGCTGGGCGTGGACGGCGACGG
CAGGCTCAAGGGCATCATGACCGGCCTGGGCGCGCTGCGCGCCGAGGTGTACCAGCCCGCGCTGGACGCGGGCGGCAGGC
TCAGGGTGACCGCCGCCGTCGGCGTGAACGGCGACGTGGCGGCGAAGGCCGAGGCGCTGCTGGCGTCCGGGGTGGACGCG
CTGGTCGTGGACACCGCGCACGGGCACCAGGAGAAGATGCTGACCGCGCTGAAGGCGGTCCGGGCGCTGTCGCCGACCGT
GCCGGTGGTGGCGGGCAACGTGGTGACCGCCGAGGGCGTGCGCGACCTGGTCGAGGCGGGCGCGGACGTGATCAAGGTCG
GGGTCGGCCCCGGCGCGATGTGCACCACCCGCATGATGACCGGCGTGGGCCGCCCGCAGTTCTCGGCGGTCGCCGAGTGC
GCCGCGCAGGCCCGCGAGCTGGGCAAGCACGTGTGGGCGGACGGCGGCGTGCGGCACCCGCGCGACGTGGCCCTCGCGCT
GGCGGCGGGCGCGGCCAGCGTCATGGTCGGCTCGTGGTTCGCGGGCACCTACGAGTCGCCCGGCGACCTGCAGCGCGACG
AGGCGGGCAGGCTCTACAAGGAGTCGTTCGGCATGGCGTCGAAGCGGGCCGTGAGCGCGCGGACCCGCACGGACAGCGCG
TTCGACCGGGCCCGCAAGGGCCTGTTCGAGGAGGGCATCTCGTCCTCGCGGATGCGCCTGGACCCGACCAGGCCGGGCGT
GGAGGACCTGCTGGACTCGATCACCGCGGGCGTGCGGTCGGCGTGCACCTACGCGGGCGCGACGACCCTGGAGGAGTTCC
ACGCGCGCGCCGTGCTGGGCGTGCAGTCGGCGGCGGGCTTCGCCGAGGGCAGGCCGCTCCCCTCGGGCTGGTGA

Protein sequence :
MRFIEGRQPANDLTYDDVFLVPGRSAVDSRFGVDLSTSDGTGATIPVVVANMTAVAGRRMAETMARRGGLVVLPQDVAPE
AVAEIVSWVKERHPVWDTPLVLSPNDSVADAFNLLHKRAHGTVVVVGQDGRPVGTVDEHALGGVDRFTRLSEVADHDVVV
LPLDTAPREVFERLGAHRAALGVDGDGRLKGIMTGLGALRAEVYQPALDAGGRLRVTAAVGVNGDVAAKAEALLASGVDA
LVVDTAHGHQEKMLTALKAVRALSPTVPVVAGNVVTAEGVRDLVEAGADVIKVGVGPGAMCTTRMMTGVGRPQFSAVAEC
AAQARELGKHVWADGGVRHPRDVALALAAGAASVMVGSWFAGTYESPGDLQRDEAGRLYKESFGMASKRAVSARTRTDSA
FDRARKGLFEEGISSSRMRLDPTRPGVEDLLDSITAGVRSACTYAGATTLEEFHARAVLGVQSAAGFAEGRPLPSGW

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CpC231_1472 YP_005683835.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 1e-139 62
CpI19_1479 YP_005685921.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 1e-139 62
cpfrc_01479 YP_003783879.1 hypothetical protein Not tested PiCp 5 Protein 7e-140 62
Cp1002_1469 YP_005681736.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 3e-140 62