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Name : leuS (Amir_7074) Accession : YP_003104711.1 Strain : Actinosynnema mirum DSM 43827 Genome accession: NC_013093 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 8219961 - 8222765 bp Length : 2805 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAGCACGGAACCGGCGGCTGACACGCCCGCCTACCGCTACACGGCGGCGCTGGCGAACGAGATCGAGCAGCGGTGGCA GCGGCGCTGGGAGGAGCGCGGCACCTTCCACGCGCCGAACCCGTCCGGTCAGCTCAAGGGCGAGGTCCCCGCCGACAAGC TGTTCGTGCAGGACATGTTCCCGTACCCGTCCGGCGCCGGCCTGCACGTCGGCCACCCGCTGGGCTTCATCGGCACGGAC GTGTACGCGCGGTACCACCGGATGACCGGCCGGAACGTGCTGCACACGATGGGCTTCGACGCGTTCGGCCTGCCCGCCGA GCAGTACGCGGTGCGCACCGGCCAGCACCCGCGCGAGACCACCAAGGCCAACATCGAGACCTACCTGCGCCAGATCCGCA GGCTGGGCCTGGGCCACGACGAGCGCCGCCGCATCTCCACGATCGACCCGGACTACTACCGCTGGACCCAGTGGATCTTC CTGCAGATCTACAACTCCTGGTTCGACGCGGACGTGAAGAAGGCCAGGCCGATCGCCGAGCTGGTCGAGCGGTTCAAGTC CGGCGAGCGCGCCACCCCGGACGGCCGCCCGTGGGCCGAGCTGTCCGCGGCCGAGCAGCAGAAGGTCCTGGGCGAGCACC GCCTGGCCTACCTGTCCGAGGCCCCGGTGAACTGGTGCCCCGGCCTGGGCACGGTGCTGGCCAACGAGGAGGTCACCTCC GACGGCCGCAGCGAGCGCGGCAACTTCCCGGTGTTCCGCCGCAACCTGCGCCAGTGGATGATGCGGATCACCGCCTACTC GGACCGCCTGGTCGACGACCTGGACCGGCTGGACTGGCCGGAGAAGGTCAAGTCCATGCAGCGCAACTGGATCGGCCGCT CCAACGGCGCGCGGGTCCGGTTCGAGGTTCGGGCCGGTGAGGGCGCCGTCGGCGCCGACGAGCGGATCGAGGTCTTCACG ACCCGCCCCGACACCCTGTTCGGCGCCACCTACGTCGTGCTGGCCCCCGAGCACCCGCTGGTCGACGCGATCGCCTCCCC CGCGCAGGCGGGCGCGATCGCCGCCTACCGCGCCGAGGTGGCCCGCAAGTCCGAGCTGGACCGGCAGGAGAGCAAGGAGA AGACCGGCGTCCCCATCGGCGCGGTCGCGGTCAACCCGGTCAACGGCGCCGAGCTGCCCGTCTACGTCGCCGACTACGTG CTGATGGGCTACGGCACCGGCGCGATCATGGCGGTGCCCGGCCAGGACCAGCGCGACTGGGACTTCGCCAAGGCGTTCGA CCTGCCGATCATCCGCACCGTCCAGCCCACCGAGGGCTTCGAGGGCGAGGCGTTCACCGGCGTCGGCCCCGCGATCAACT CCGGCTTCCTGGACGGCATGGACGTCGCCGAGGCCAAGAAGGCGATCATCGCCTGGCTGGAGGAGCGCGGCGCGGGCGAG GGCACCGTGCAGTACAAGCTGCGCGACTGGCTGTTCTCCCGGCAGCGGTACTGGGGCGAGCCCTTCCCGATCGTCTACGA CGAGGACGGCACCCCGATCGCGCTGCCCGAGTCGCACCTGCCGGTCGTGCTGCCCGAGGTGGACGACTACTCGCCGCGCA CCTTCGAGCCGGACGACGCGAACTCCGAGCCGTCCCCGCCGCTGACCCGCGCGCAGGAGTGGGTGGAGGTCGAGCTGGAC CTGGGCGACGGGCCCAAGCGGTACCGCCGCGAGACCAACACCATGCCCAACTGGGCCGGTTCCTGCTGGTACCAGCTGCG CTACGTCGACCCGACCGAGCCCGGCCGGTTCGTGGACGCCGAGAACGAGCAGTACTGGCTGGGCCCGCGCCCTGCCGAGC ACGGCGCGAACGACCCCGGCGGCGTCGACCTGTACATCGGCGGCGTCGAGCACGCGGTGCTGCACCTGCTGTACTCGCGG TTCTGGCAGAAGGTGCTGTTCGACCTGGGCCACGTGTCCGGCGACGAGCCGTACCGCAGGCTGTTCAACCAGGGCTACAT CGAGGCGTACGCGTACACCGACGCGCGCGGCGCGTACGTGACCGCCGAGGAGGTCGTGGAGAAGGACGGCAAGTTCTTCC ACGACGGCGCCGAGGTCTCCCGCGAGTACGGGAAGATGGGCAAGAGCCTGAAGAACGTCGTCACGCCGGACGAGATGTGC GCGAACTACGGCGCCGACACGTTCCGGGTGTACGAGATGTCGATGGGCCCGATGGACGTGTCGCGGCCGTGGGCGACCAA GGACGTCGTGGGCGCGCAGCGGTTCCTGCAGCGGCTGTGGCGCAACCTGGTCGACGAGGACAGCGGCGAGCTGCGGGTGG CCGACGTCGAGCCGTCCGAGGACGCGCTGCGGCTGCTGCACAAGACCATCGCGGGCGTGCACGACGACTACGCGAACCTG CGCTACAACACGGCGGTCGCGAAGCTGATCGAGCTGAACAACCACGTCACCAAGCATTACCCGGCGGGCGCGCCGAGGGC GCTGGCCGGTCCGGTCGTGCAGCTGCTGGCCCCGCTGGCGCCGCACGTGGCGGAGGAGCTGTGGGAGCGGCTGGGCGGCG GCGGTGACTCGCTGGCGCACGGGCCGTTCCCGGTGGCCGAGGAGCGCTACCTGGTGGAGGACACCGTCCTGTACCCGGTG CAGGTGGGAGGCAAGGTCAAGGCGCGGGTGACGGTGTCGGCGTCCGCCTCGCCGGACGAGGTGAAGGCCGCCGCGCTGGG CGACCCGGCGGTGGCGGCGCTGCTGACCGGCGAGCCGAGGAAGGTCATCGTGGTGCCGGGCAGGCTGGTCAACATCGTGC TGTGA Protein sequence : MSTEPAADTPAYRYTAALANEIEQRWQRRWEERGTFHAPNPSGQLKGEVPADKLFVQDMFPYPSGAGLHVGHPLGFIGTD VYARYHRMTGRNVLHTMGFDAFGLPAEQYAVRTGQHPRETTKANIETYLRQIRRLGLGHDERRRISTIDPDYYRWTQWIF LQIYNSWFDADVKKARPIAELVERFKSGERATPDGRPWAELSAAEQQKVLGEHRLAYLSEAPVNWCPGLGTVLANEEVTS DGRSERGNFPVFRRNLRQWMMRITAYSDRLVDDLDRLDWPEKVKSMQRNWIGRSNGARVRFEVRAGEGAVGADERIEVFT TRPDTLFGATYVVLAPEHPLVDAIASPAQAGAIAAYRAEVARKSELDRQESKEKTGVPIGAVAVNPVNGAELPVYVADYV LMGYGTGAIMAVPGQDQRDWDFAKAFDLPIIRTVQPTEGFEGEAFTGVGPAINSGFLDGMDVAEAKKAIIAWLEERGAGE GTVQYKLRDWLFSRQRYWGEPFPIVYDEDGTPIALPESHLPVVLPEVDDYSPRTFEPDDANSEPSPPLTRAQEWVEVELD LGDGPKRYRRETNTMPNWAGSCWYQLRYVDPTEPGRFVDAENEQYWLGPRPAEHGANDPGGVDLYIGGVEHAVLHLLYSR FWQKVLFDLGHVSGDEPYRRLFNQGYIEAYAYTDARGAYVTAEEVVEKDGKFFHDGAEVSREYGKMGKSLKNVVTPDEMC ANYGADTFRVYEMSMGPMDVSRPWATKDVVGAQRFLQRLWRNLVDEDSGELRVADVEPSEDALRLLHKTIAGVHDDYANL RYNTAVAKLIELNNHVTKHYPAGAPRALAGPVVQLLAPLAPHVAEELWERLGGGGDSLAHGPFPVAEERYLVEDTVLYPV QVGGKVKARVTVSASASPDEVKAAALGDPAVAALLTGEPRKVIVVPGRLVNIVL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 9e-168 | 46 |
