Gene Information

Name : hemC (Amir_6729)
Accession : YP_003104372.1
Strain : Actinosynnema mirum DSM 43827
Genome accession: NC_013093
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 7862024 - 7862965 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
GTGAACCGCACCCTGAGGATCGGCACCCGAGGAAGCGCGCTGGCGCTGGCGCAGACCGGCACGGTGGCCGAGGCCCTGCG
GGCCGCGGGCGCCCAGGTGGAGATCGTCACGGTCTCCACGCCCGGTGACCGCTCGCACGCGCCCATCGCGGAGATCGGCA
TCGGGGTCTTCACCTCGGCGCTGCGCGACGCGCTCGCGCACGGCGAGGTCGACGTCGCCGTGCACTCGTACAAGGACCTG
CCCACCGCCCCGGACACCCGGCTGTCGCTGGCCGCGATCCCGCAGCGCGAGGACCCGCGCGACGCGCTGGTCGCCCGCGA
CGGGCTGACCCTGGGCGAGCTGCCCCCCGGCTCCAAGGTCGGCACGGGCTCCCCGCGCCGCGCCACGCAGCTGGCGGCGC
TCGGCCTCGGTCTGGAGATCCTGCCCATCCGGGGCAACATCGACAGCCGCATGGCCCGCGTCTTCGACGGCGAGCTCGAC
GCCGTCGTGCTCGCCCGCGCCGGGATCTCCCGGCTCGGCCGGGTCGAGAACATCACCGAGGTCCTCGACCCGATCCAGAT
GCTCCCCGCGCCCGCGCAGGGCGCACTGGCGATCGAGTGCCGGGTCGACGACGTCGACACCGAGCACTTGCTCCGCTCCA
CGCTCGACGATTCGGCCAGTCGGGCCGCTGTCACCGCCGAGCGCGCCATGCTGGCCGCGCTCGAAGCCGGGTGCAGCGCG
CCGGTCGGCGCACTGGCCGATGTGGTGGAAGACCTCGACGACGAGGGAGCCGCGGTCCTCCGCATCTCCCTCCGCGGGGT
CGTGGCGGCGGAGGACGGCGACCTCCTCCGCGCGTCGGCCACCGGTGACTTGACCGCAGCAGAGGAACTCGGCCGCGCGC
TGGCCGCCGAGTTGCTCGACCTCTCCGGCCACGCCGCAGCGCGGTCGGCGGGGCGTAGTTGA

Protein sequence :
MNRTLRIGTRGSALALAQTGTVAEALRAAGAQVEIVTVSTPGDRSHAPIAEIGIGVFTSALRDALAHGEVDVAVHSYKDL
PTAPDTRLSLAAIPQREDPRDALVARDGLTLGELPPGSKVGTGSPRRATQLAALGLGLEILPIRGNIDSRMARVFDGELD
AVVLARAGISRLGRVENITEVLDPIQMLPAPAQGALAIECRVDDVDTEHLLRSTLDDSASRAAVTAERAMLAALEAGCSA
PVGALADVVEDLDDEGAAVLRISLRGVVAAEDGDLLRASATGDLTAAEELGRALAAELLDLSGHAAARSAGRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-35 41
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-35 41