Gene Information

Name : guaA (Amir_6529)
Accession : YP_003104175.1
Strain : Actinosynnema mirum DSM 43827
Genome accession: NC_013093
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 7669002 - 7670561 bp
Length : 1560 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGGCCGACAGCAGCAACCGCCCCGTCCTGGTGGTGGACTTCGGCGCGCAGTACGCGCAGTTGATCGCACGCCGGGTCCG
CGAGGCCCAGGTGTACTCGGAGGTCGTCCCGCACACCACCCCGGTGGCCGAGCTGCTGGCGAAGGACCCCGCGGCCATCG
TGCTGTCCGGCGGCCCGTCCAGCGTGTACGAGCCCGGCGCGCCCCAGGTGGACCCCGCCCTGTTCGACGCGGGCGTCCCG
GTGTTCGGCATCTGCTACGGCTTCCAGGCGATGGCGGGGGCCCTCGGCGGCACCGTCGAGCACACCGGAACCCGCGAGTA
CGGCCGCACCGAGCTGGTCCTGCCCCCGACGAGCGGCGTGCTCCACGACGACCTGCCCGGCACCCACCCGGTGTGGATGA
GCCACGGCGACTGCGTCACCGGCGCCCCCGAGGGCTTCACGGTGACCGCGTCCAGCGACGGCGCCCCCGTGGCCGCCTTC
GAGAACCGCGAGCGGCGCTTCGCGGGCGTCCAGTACCACCCGGAGGTCGGGCACTCCCCGCACGGCCAGGAGGTGCTGCG
CCGGTTCCTGCACGAGATCGCGGGCATCCGGCCGCAGTGGACCACCGCGTCCATCGTGGAGGAGCAGGTCGAGCGCATCC
GCGCCCAGGTCGGCGAGGGCCGCGCGATCTGCGGCCTGTCCGGCGGCGTGGACTCGGCGGTGGCGGCGGCGCTCGTGCAG
CGCGCCATCGGCGACCGGCTGACCTGCGTGTTCGTCGACCACGGCCTGCTGCGCGCGGGCGAGCGCACCCAGGTGGAGCG
CGACTTCGTGGCCTCCACCGGGGTCAACCTGGTCACCGTCGACGCGCGGCAGCGGTTCCTCGACGCGCTCGCGGGCGTGA
CCGACCCCGAGGAGAAGCGCAAGATCATCGGCCGGGAGTTCATCCGGGTCTTCGAGCAGGCCGAGCGCGACCTCAAGGCC
GAGGGCGACTACGGCTTCCTCGTCCAGGGCACGCTCTACCCGGACGTGGTCGAGTCCGGCGGCGGCGCGGGCGCGGCGAA
CATCAAGAGCCACCACAACGTCGGCGGCCTCCCGGACGACCTGCAGTTCGAGCTGGTCGAGCCGCTGCGCGCGCTGTTCA
AGGACGAGGTGCGCAAGGTCGGCGCCGAGCTGGGCCTGCCGGAGACGATCGTGCAGCGCCAGCCGTTCCCCGGCCCCGGC
CTGGGCATCCGCATCATCGGCGAGGTGACCGCCGAGCGGCTGGACATCCTGCGCAAGGCCGACGCCATCGCCCGCGAGGA
GCTGACGGCGGCCGGTCTGGACCGCACGATCTGGCAGTGCCCGGTCGTGCTGCTGGCCGACGTGCGCAGCGTCGGCGTGC
AGGGCGACGGGCGCACCTACGGTCACCCGATCGTGCTGCGGCCGGTGTCCAGCGAGGACGCCATGACCGCCGACTGGACC
CGCCTGCCCTACGAGGTGCTGGAGCGGGTGTCCACCCGCATCACCAACGAGGTGGCCGAGGTCAACCGGGTCGTGCTCGA
CGTGACGAGCAAGCCGCCGGGCACCATCGAGTGGGAGTGA

Protein sequence :
MADSSNRPVLVVDFGAQYAQLIARRVREAQVYSEVVPHTTPVAELLAKDPAAIVLSGGPSSVYEPGAPQVDPALFDAGVP
VFGICYGFQAMAGALGGTVEHTGTREYGRTELVLPPTSGVLHDDLPGTHPVWMSHGDCVTGAPEGFTVTASSDGAPVAAF
ENRERRFAGVQYHPEVGHSPHGQEVLRRFLHEIAGIRPQWTTASIVEEQVERIRAQVGEGRAICGLSGGVDSAVAAALVQ
RAIGDRLTCVFVDHGLLRAGERTQVERDFVASTGVNLVTVDARQRFLDALAGVTDPEEKRKIIGREFIRVFEQAERDLKA
EGDYGFLVQGTLYPDVVESGGGAGAANIKSHHNVGGLPDDLQFELVEPLRALFKDEVRKVGAELGLPETIVQRQPFPGPG
LGIRIIGEVTAERLDILRKADAIAREELTAAGLDRTIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWT
RLPYEVLERVSTRITNEVAEVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 76
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-140 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-140 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-140 52