Gene Information

Name : Amir_0612 (Amir_0612)
Accession : YP_003098421.1
Strain : Actinosynnema mirum DSM 43827
Genome accession: NC_013093
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 674727 - 675413 bp
Length : 687 bp
Strand : +
Note : PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sfu:Sfum_2007 two component transcriptional regulator, winged helix family

DNA sequence : 
ATGCGCATCCTCGTTGTCGACGACGACAGGGCCGTGCGTGAGTCGCTCCGCCGCTCACTGCAGTTCAACGGCTACCAGGT
GGACCTCGCGGGCGACGGCCAGCAGGCGCTGGAGTCGGTCCTGTCGCAGCGCCCGGACGCCATGGTCCTGGACGTGATGA
TGCCCAGGCTCGACGGCCTGGAGGTCTGCCGGAGGTTGCGCAGCACGGGCGACGACCTGCCCATACTCGTGCTCACCGCG
CGGGACGCGGTGAGCGACCGGGTCTCCGGTCTGGACGCGGGGGCCGACGACTACCTGCCGAAGCCGTTCGCGCTGGAGGA
GCTGCTGGCCAGGTTGCGCGCCCTGCTGCGGCGCACCGCCACCGACGTGGAGGAGCCGGTCAACCTGCTGCGCTTCGCCG
ACCTGGAGCTGGACCCCGGCACCAGGGACGTCCGCAGGGGCGAGCGGCCCATCAGCCTCACCCGCACCGAGTTCGCGCTG
CTGGAGCTGTTCCTGGCGCACCCCAAGCAGGTGCTCACCAGGGGGCGCATCCTGGAGGACGTGTGGGGCTACGACTTCCC
CACCTCCGGGAACGCGCTGGAGGTGTACGTCGGCTACCTGCGGCGCAAGACCGAGGCGGGCGGCGAGCCCCGGCTGCTGC
ACACGGTGCGCGGCGTCGGCTACGTGCTCAGGGAGACGCCCCCGTGA

Protein sequence : 
MRILVVDDDRAVRESLRRSLQFNGYQVDLAGDGQQALESVLSQRPDAMVLDVMMPRLDGLEVCRRLRSTGDDLPILVLTA
RDAVSDRVSGLDAGADDYLPKPFALEELLARLRALLRRTATDVEEPVNLLRFADLELDPGTRDVRRGERPISLTRTEFAL
LELFLAHPKQVLTRGRILEDVWGYDFPTSGNALEVYVGYLRRKTEAGGEPRLLHTVRGVGYVLRETPP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-31 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator HE999704.1.gene1528. Protein 2e-38 46
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator AE000516.2.gene3505. Protein 1e-34 46
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator BAC0638 Protein 4e-27 46
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator BAC0083 Protein 5e-34 45
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator BAC0125 Protein 8e-32 44
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator BAC0347 Protein 5e-30 44
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator BAC0111 Protein 2e-34 44
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator BAC0308 Protein 2e-31 43
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator BAC0197 Protein 5e-29 43
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator NC_002516.2.879194.p Protein 5e-23 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator VFG1390 Protein 2e-77 80
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator VFG1386 Protein 8e-48 53
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator VFG1389 Protein 5e-44 52
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator VFG0596 Protein 4e-32 42
Amir_0612 YP_003098421.1 winged helix family two component transcriptional regulator VFG0473 Protein 4e-21 41