Gene Information

Name : Amir_5186 (Amir_5186)
Accession : YP_003102853.1
Strain : Actinosynnema mirum DSM 43827
Genome accession: NC_013093
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 6179098 - 6181191 bp
Length : 2094 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGTCCGATGACATCACCCGGCTGACCGAGGCCACCGTCCCCGCCGACTGGACCGCGCTCGACAAGCGCGCCGTCGACAC
CGCGCGTGTCCTCGCCGCCGACGCCGTCCAGAAGGTCGGCAACGGCCACCCCGGCACCGCGATGAGCCTCGCCCCCGTGG
CCTACTCGCTGTTCCAGCGGGTGATGCGCCACGACCCGGCCGACGCCGACTGGATCGGCCGCGACCGCTTCGTGCTGTCG
GCGGGTCACTCCAGCCTGACGCTGTACATCCAGCTGTACCTGGCGGGCTACGGCCTGGAGCTGGACGACCTGAAGGCGCT
GCGCACCTGGGGTTCCAAGACCCCCGGCCACCCGGAGCACCGCCACACCCCCGGTGTGGAGATCACCACCGGCCCGCTGG
GCCAGGGCCTCGCCTCGGCCGTGGGCATGGCGATGGCCGCCCGCCGCGAGCGCGGCCTGTTCGACCCGGAGGCCCCGGCG
GGCGAGAGCCCATTCGACCACCAGGTCTACGTGATCGCCTCCGACGGCGACATCGAGGAGGGCGTCACCTCCGAGGCCTC
GTCGATCGCGGGCCACCAGCAGCTGGGCAACCTCACGCTGATCTACGACGACAACAAGATCTCGATCGAGGACGACACCG
CGATCGCGCTGTCCGAGGACACCGCCAAGCGCTACGAGGCGTACGGCTGGCACGTGCAGGTCGTGGAGTCCGGCGAGAAC
ATCTCCGGCATCCTGGCCGCGCTGGAGGCCGCCCGCGCCGAGACGGCCCGCCCGTCGCTGGTCGTGCTGCGCACGATCAT
CGGCTTCCCGGCGCCGAACAAGATGAACACCGGCAAGATCCACGGCTCCGCGCTGGGCGACGCCGAGGTGGCCGAGGTCA
AGAAGGCGCTGGGCTTCGACCCGGAGCAGACCTTCGAGGTCTCGGACGAGGTGATCAACCACACCCGCTCGGTCATCAAG
CGCGGTGAGGCCGCCAAGGCCGAGTGGCAGAAGTCCTTCGACGCGTGGGCGGAGGCGAACCCGGAGCGCAAGGCGCTGCT
GGACCGCCTGATCGGCCGCGACCTGCCCGAGGGCTGGACCGACGCGCTGCCCGTGTGGGAGCCGGACGCCAAGGGCGTCG
CGACCCGCAAGGCGTCCGGCGACGTGCTGTCCGCGCTGGCCCCGGTCCTGCCGGAGCTGTGGGGCGGCTCGGCCGACCTG
GCCGAGTCGAACAACACCACGATGAAGGGCGCGGACTCGTTCGGCCCGGAGAGCTCCTCCACGAGCACGTGGAGCGCGAA
CCCGTACGGCCGCACGCTGCACTTCGGCATCCGCGAGCACGCGATGGGCTCGATCCTCAACGGCATCGCGCTGCACGGCC
CGACCCGCCCGTACGGCGGCACGTTCCTGGTGTTCAGCGACTACATGCGCCCGGCCGTGCGCCTGGCCGCGCTGATGAAG
TCCGCGGTCACCTACGTGTGGACGCACGACTCCATCGGCCTGGGCGAGGACGGCCCGACGCACCAGCCGATCGAGCACCT
GGCCGCGCTGCGCGCGATCCCCGGTCTCGCGGTGGTGCGCCCCGGCGACGCCAACGAGACCTCGGCGTCGTGGCGGGCCA
TCATCGAGAACCCGACCGGCCCGGCCGGCCTCGCCCTGACCAGGCAGAACCTCCCGGTGCTCGAGGGCACCAGGGAGAAG
GCCGCCGAGGGCGTCGCCAAGGGCGGCTACGTGCTGGAGGACGCCGCGAACGGCGCTCCCGAGGTCGTGCTGATCGCCAC
CGGCTCCGAGCTGCAGATGGCGGTCGAGGCGCGGAAGGTCCTGGAGGCCGACGGCGTTGCAGCGCGTGTGGTGTCCATGC
CGTGCGTCGAGTGGTTCGACGCCCAGGACGAGGCGTACCGCGAGTCGGTCATCCCGTCCTCGGTGAAGGCGCGCGTCGTG
GTCGAGGCGGGCATCGCCCAGCCGTGGCACCGGTTCACCGGCGACGCGGGCGAGATCGTCTCGATCGAGCACTTCGGCGC
CTCCGCCGACTACCAGACGCTGTTCCGCGAGTTCGGCTTCACGACCGAGAACGTCGTGGCCGCCGCCCGCCGGTCGCTGG
ACGCCACCCGCTGA

Protein sequence :
MSDDITRLTEATVPADWTALDKRAVDTARVLAADAVQKVGNGHPGTAMSLAPVAYSLFQRVMRHDPADADWIGRDRFVLS
AGHSSLTLYIQLYLAGYGLELDDLKALRTWGSKTPGHPEHRHTPGVEITTGPLGQGLASAVGMAMAARRERGLFDPEAPA
GESPFDHQVYVIASDGDIEEGVTSEASSIAGHQQLGNLTLIYDDNKISIEDDTAIALSEDTAKRYEAYGWHVQVVESGEN
ISGILAALEAARAETARPSLVVLRTIIGFPAPNKMNTGKIHGSALGDAEVAEVKKALGFDPEQTFEVSDEVINHTRSVIK
RGEAAKAEWQKSFDAWAEANPERKALLDRLIGRDLPEGWTDALPVWEPDAKGVATRKASGDVLSALAPVLPELWGGSADL
AESNNTTMKGADSFGPESSSTSTWSANPYGRTLHFGIREHAMGSILNGIALHGPTRPYGGTFLVFSDYMRPAVRLAALMK
SAVTYVWTHDSIGLGEDGPTHQPIEHLAALRAIPGLAVVRPGDANETSASWRAIIENPTGPAGLALTRQNLPVLEGTREK
AAEGVAKGGYVLEDAANGAPEVVLIATGSELQMAVEARKVLEADGVAARVVSMPCVEWFDAQDEAYRESVIPSSVKARVV
VEAGIAQPWHRFTGDAGEIVSIEHFGASADYQTLFREFGFTTENVVAAARRSLDATR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-128 46
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 6e-125 44