Gene Information

Name : Amir_0425 (Amir_0425)
Accession : YP_003098238.1
Strain : Actinosynnema mirum DSM 43827
Genome accession: NC_013093
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 459516 - 461159 bp
Length : 1644 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
GTGACGGCACTCGGGGACGGCTCGGTCAGGCCGAGCGTCACCACCGGGCCGATCCGGGGGTCCCGCAAGGTCCACCGCGA
CGCGGAGGACGGCGTGCGGGTCCCGTTCCGCAGGGTCGAGCTCACCGACGGCGACCACTTCGACCTGTACGACACCTCCG
GGCCTTACACGGCCGGGGACGTCGACGTGCGCGAGGGACTGGAGAAGATCCGCGCCGGCTGGATCTCGGCGCGCGAGCCC
GTGAACGGGGCAGCCACCCAGCTGGCCTGGGCGCGGGCGGGCGTGATCACCCCGGAGATGCGGTTCGCGGCGCTGCGCGA
GTCGCTGGCGCCGGAGTTCGTGCGCGACGAGGTCGCCGCGGGGCGCGCGGTGATCCCGGCCAACCGCAACCACCCGGAGT
CCGAGCCGATGGTCATCGGCAAGGGGTTCCTGGTGAAGGTCAACGCCAACATCGGCAACTCGGCGGTGACCTCGTCCGTC
GAGGAGGAGGTGGAGAAGATGGTGTGGGCGACCCGCTGGGGCGCCGACACCGTGATGGACCTGTCGACCGGCAAGCGCAT
CCACGAGACCCGCGAGTGGATCATCCGCAACTCGCCGGTCCCCGTGGGGACGGTGCCGATCTACCAGGCGCTGGAGAAGG
TCGGCGGGGATCCGGCCGCGCTGTCCTGGGAGGTGTACCGGGACACCGTCGTGGAGCAGGCCGAGCAGGGCGTGGACTAC
ATGACGGTGCACGCGGGCGTGCTGCTGCGGTACGTGCCGCTGACGGCGCGGCGGGTCACCGGGATCGTCTCGCGCGGCGG
CTCGATCATGGCCGCGTGGTGCCTGGCGCACCACGAGGAGAGCTTCCTGTACACCCGGTTCGCCGAGCTGTGCGAGATCC
TGCGCCAGTACGACGTGACGTTCTCGCTGGGCGACGGGCTGCGGCCGGGGTCGATCGCGGACGCCAACGACGAGGCCCAG
TTCGCCGAGCTGCGCACCCTGGGCGAGCTGGCGCGGGTGGCCAGGGCGCACGACGTGCAGGTGATGATCGAGGGGCCCGG
CCACGTGCCGCTGCACAAGATCGCGGAGAACGTGCGGCTGGAGCAGGAGTGGTGCGACGGCGCGCCGTTCTACACGCTCG
GCCCGCTGGCCACCGACGTCGCGCCCGCCTACGACCACATCACGTCGGCGATCGGCGCGGCGCAGATCGGGGCGCTCGGC
ACGGCCATGCTCTGCTACGTGACCCCGAAGGAGCACCTGGGGCTGCCGGACCGGGACGACGTGAAGACCGGCGTGATCAC
GTACAAGATCGCCGCGCACGCCGCCGACCTCGCCAAGGGCCACCCCGGCGCGCAGGCGTGGGACGACGCGCTGTCCAGGG
CCAGGTTCGAGTTCCGCTGGGAGGACCAGTTCAACCTCTCGCTCGACCCGGACACCGCGCGCGAGTTCCACGACCGGACG
CTCCCGGCGGAGCCCGCGAAGACGGCGCACTTCTGCTCGATGTGCGGGCCGAAGTTCTGCTCGATGCGGATCACGCAGGA
CGTGCGGCGCTACGCTGAGGAGCGGGGTCTGTCCACTGTGGAAGCGATTGAGGCGGGTATGGCCGAGAAGGCGCACGAGT
TCGACGACCGGGGCGGCAAGGTCTACCTGCCGGTCGTGGACTGA

Protein sequence :
MTALGDGSVRPSVTTGPIRGSRKVHRDAEDGVRVPFRRVELTDGDHFDLYDTSGPYTAGDVDVREGLEKIRAGWISAREP
VNGAATQLAWARAGVITPEMRFAALRESLAPEFVRDEVAAGRAVIPANRNHPESEPMVIGKGFLVKVNANIGNSAVTSSV
EEEVEKMVWATRWGADTVMDLSTGKRIHETREWIIRNSPVPVGTVPIYQALEKVGGDPAALSWEVYRDTVVEQAEQGVDY
MTVHAGVLLRYVPLTARRVTGIVSRGGSIMAAWCLAHHEESFLYTRFAELCEILRQYDVTFSLGDGLRPGSIADANDEAQ
FAELRTLGELARVARAHDVQVMIEGPGHVPLHKIAENVRLEQEWCDGAPFYTLGPLATDVAPAYDHITSAIGAAQIGALG
TAMLCYVTPKEHLGLPDRDDVKTGVITYKIAAHAADLAKGHPGAQAWDDALSRARFEFRWEDQFNLSLDPDTAREFHDRT
LPAEPAKTAHFCSMCGPKFCSMRITQDVRRYAEERGLSTVEAIEAGMAEKAHEFDDRGGKVYLPVVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 6e-167 60
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 6e-167 60
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 4e-158 60