Gene Information

Name : Amir_2344 (Amir_2344)
Accession : YP_003100130.1
Strain : Actinosynnema mirum DSM 43827
Genome accession: NC_013093
Putative virulence/resistance : Virulence
Product : FliI/YscN family ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.15
Position : 2600996 - 2602315 bp
Length : 1320 bp
Strand : -
Note : KEGG: afw:Anae109_2216 FliI/YscN family ATPase; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: ATPase AAA

DNA sequence :
GTGACCGGACTGCTGGACGAGCGTTTCGCACCTGCCCTGGCCGCGGCGAAGCCGCAGGTCATCGGCCGGGTGACCGGTGT
GGTGGGGTTGTCGGTGACGGTGGCGGGCATCAGCGCCCGCATCGGCGACCTGGTGCGGATCGGGTCCGGCGGTCAGGAAG
TGCTGGCCGAGGTGGTGGCGCTGGGCGCGGGCAAGATCACCTGCCTGCCGCTGGGCGCGCTGGGCGGCATCGGCCTCGGC
GCCGAGGTCGTGAGCACGAACCGGCCGCTGCAGATCGCCGTGGGCGAGCAGCTGCGCGGCCGGGTGCTGGACGGGCTGGG
GCGGCCGATGGACGGCGGGCCGCCGCTGGTCGGGCTGGAGTCGGTGACGGTGGACATGACCCCGCCGTCGGCGCTGCAGC
GCCAGCTGATCGACAAGCCGCTGCAGCTGGGCGTGCGCGCGCTGGACACGATGGTGCCGTGCGGGCAGGGCCAGCGCATC
GGGATCTTCGCGGGCTCGGGCGTGGGCAAGTCGAGCCTGCTGTCGATGATCACGCGCGGCACCGAGGCGGAGATCACCGT
GGTCGCCCTGATCGGCGAGCGCGGTCGCGAGGTGCGCGAGTTCATCGAGAACGACCTGGGCCCCGAGGGCCTGGCCCGCT
CGGTCGTGGTCGTGGCGACCTCCGACCAGCCGCCGATGGTGCGGCTGCGCGCGGGGTTCGTGGCCACCCGCATCGCCGAG
TGGTACCGGGACCGGGGCGCGAACGCGCTGCTGATGATGGACAGCCTCACCCGCATCGCGATGGCGCAGCGCGAGGTGGG
CCTGTCCGCGGGCGAGCCGCCCGCGACGCGGGGCTTCCCGCCGTCGGTGTTCGCGCTGATGCCGACCCTGCTGGAGCGGG
CCGGACCGGCCGAGCGCGGCAGCATCACCGGCCTGTACACGGTGCTGGTGGAGGGCGACGACCACAACGAGCCGATCGCC
GACACCGCCCGGTCCATCCTGGACGGCCACGTGGTGCTGGACCGCAGGCTCGCCACCTCGGGGCACTTCCCCAGCATCGA
CGTGCTGGAGTCGGTGTCGCGGGTGACCGGCGCGGTGACCACGCCCGAGCAGCGCGCCGACGCGGCGCAGCTGCGCAGGC
TGCTGGCGGCCCGCCGGGACGTGCGGGAGCTGGTGGAGATCGGCGCCTACGTCGGCGGCACGAACCTGGACGCGGACCGC
GCCATGGCGCTGGAGCCGCGCATCAACGGCCTGCTCACCCAGGACATCCACGCGCGCACCAGCGCGGAGTCGTCCTGGGA
GGAGCTGCGGGAACTGCTGCACGGGGGTATGCGGGGATGA

Protein sequence :
MTGLLDERFAPALAAAKPQVIGRVTGVVGLSVTVAGISARIGDLVRIGSGGQEVLAEVVALGAGKITCLPLGALGGIGLG
AEVVSTNRPLQIAVGEQLRGRVLDGLGRPMDGGPPLVGLESVTVDMTPPSALQRQLIDKPLQLGVRALDTMVPCGQGQRI
GIFAGSGVGKSSLLSMITRGTEAEITVVALIGERGREVREFIENDLGPEGLARSVVVVATSDQPPMVRLRAGFVATRIAE
WYRDRGANALLMMDSLTRIAMAQREVGLSAGEPPATRGFPPSVFALMPTLLERAGPAERGSITGLYTVLVEGDDHNEPIA
DTARSILDGHVVLDRRLATSGHFPSIDVLESVSRVTGAVTTPEQRADAAQLRRLLAARRDVRELVEIGAYVGGTNLDADR
AMALEPRINGLLTQDIHARTSAESSWEELRELLHGGMRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-77 57
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-82 53
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-78 53
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-78 53
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-75 52
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-75 52
escN YP_003223475.1 translocator EscN Virulence LEE Protein 9e-73 52
escN YP_003236088.1 translocator EscN Virulence LEE Protein 7e-73 52
escN AAC38383.1 EscN Virulence LEE Protein 1e-72 52
escN AAC31513.1 L0034 Virulence LEE Protein 1e-72 52
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-72 52
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-72 52
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-72 52
escN CAI43874.1 EscN protein Virulence LEE Protein 7e-73 52
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-72 52
escN AAK26715.1 EscN Virulence LEE Protein 4e-72 51
escN AAL57542.1 EscN Virulence LEE Protein 4e-72 51
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-72 51
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-74 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-74 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-72 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-72 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-72 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-72 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-72 49
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-69 48
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-69 48
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-62 48
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-75 47
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-75 47
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-75 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-60 47
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-71 46
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 7e-61 46
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 7e-61 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-65 46
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-60 45
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-59 45
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 6e-59 45
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-59 45
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-59 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 4e-58 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-59 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-60 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-60 44
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 7e-60 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-55 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-56 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-56 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-56 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG0192 Protein 5e-87 52
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG0390 Protein 1e-81 52
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG2331 Protein 2e-76 52
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG0730 Protein 6e-73 52
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG0812 Protein 6e-73 52
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG0048 Protein 3e-83 50
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG2144 Protein 8e-82 49
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG0515 Protein 1e-72 49
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG1254 Protein 8e-75 47
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG0555 Protein 3e-59 45
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG1778 Protein 4e-60 45
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG2459 Protein 1e-57 45
Amir_2344 YP_003100130.1 FliI/YscN family ATPase VFG1008 Protein 2e-53 41