Gene Information

Name : Amir_2178 (Amir_2178)
Accession : YP_003099969.1
Strain : Actinosynnema mirum DSM 43827
Genome accession: NC_013093
Putative virulence/resistance : Resistance
Product : beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2367
EC number : 3.5.2.6
Position : 2408563 - 2409540 bp
Length : 978 bp
Strand : -
Note : PFAM: beta-lactamase; KEGG: bcj:BCAM2165 beta-lactamase, class A

DNA sequence :
ATGGCTGACACTTCGCCAGGGGCCGCGCGGCGCAGGACGCTGCTCGCGGCGCTGCTGGGCGTCCCGGTGCTGGGGGTCCC
GCTGCTGGGCTCCTGCTCGACGGCCGGTCCCGCCGCGCCACCCCCGTCGACGGGAGCCGCGCCGTCCGGGACCACGCCGT
CCGGGCCGGGCGGCGCGGGCGAGGCGGTGAGCGCCGAGCTGCCGGAGCTGGCCGAGCTGGAGGAGCGGCACGGGGCGCGG
CTGGGCGTGCGGGTGGTCGACACCGGGTCGGGGGCGGCCGTGGGGCACCGGGCGGACGAGCGGTTCCCGGTGTGCTCGCT
GATCAGCGCGTACGCGGCGGGGGCGCTGCTGGTGGCCAACGACTGGGCGGACGGGTTCTTCCAGCAGGTGATCACCTACG
AGCGGGCGGAGCTGATCGGGAACTCGCCGGTGACCGGGTCGCGGGTGGACGGCGGCATGACCGTGGCCGAGCTGTGCGAC
GCGGCGATCGCGCACGACGACAGCACGGCGCTCAACGAGCTGCTGTCGCTGGTCGGCGGGCCGGAGGCGATCACCGCGTT
CGCGTTCGCGCTGGGCGACGAGCAGACCAGGTTGGACCGCTGGGAGCCGGACCTGAACGCGGCCGAGCCGGGCGACGAGC
GGGACACGTCGACGCCGGGCGCGCTGGCCGCCGGGTACCGGAACCTGGTGCTGGGGACGGCGCTGGAGGGCGCGCGGGAG
CGGGCGGAGCTGCGCGGGTGGCTGGAGGGCGGCGGGACGGTGCTGCGCTCGGTCGTGCCGCGCGGGTGGGTGGTCGGCGG
GAAGCCGGGCGCGGCGGAGTACGGGACGCGGTGCGACGCGGCGATCGCCTGGCCCCCGGACCGCGACCCGCTGGTGGTGG
TGCTGATGTCGACCAGGCCGGAGCGGGACGCGCGCGCCGACGGGACGCTGCTGGGCGACGCGGCGCGCGTGGCGCTGGGG
GCCATGGGGGTGGGGTGA

Protein sequence :
MADTSPGAARRRTLLAALLGVPVLGVPLLGSCSTAGPAAPPPSTGAAPSGTTPSGPGGAGEAVSAELPELAELEERHGAR
LGVRVVDTGSGAAVGHRADERFPVCSLISAYAAGALLVANDWADGFFQQVITYERAELIGNSPVTGSRVDGGMTVAELCD
AAIAHDDSTALNELLSLVGGPEAITAFAFALGDEQTRLDRWEPDLNAAEPGDERDTSTPGALAAGYRNLVLGTALEGARE
RAELRGWLEGGGTVLRSVVPRGWVVGGKPGAAEYGTRCDAAIAWPPDRDPLVVVLMSTRPERDARADGTLLGDAARVALG
AMGVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaCTX-M2 ACF06162.1 beta-lactamase CTX-M2 Not tested Tn5036-like Protein 3e-45 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Amir_2178 YP_003099969.1 beta-lactamase HQ913565.1.gene1.p01 Protein 1e-44 45
Amir_2178 YP_003099969.1 beta-lactamase FJ214369.1.gene1.p1 Protein 4e-44 45
Amir_2178 YP_003099969.1 beta-lactamase EF581888.1.gene1.p01 Protein 8e-45 45
Amir_2178 YP_003099969.1 beta-lactamase AF174129.3.gene9.p01 Protein 3e-44 45
Amir_2178 YP_003099969.1 beta-lactamase HQ166709.1.gene1.p01 Protein 2e-43 45
Amir_2178 YP_003099969.1 beta-lactamase AF325133.1.gene1.p1 Protein 1e-44 45
Amir_2178 YP_003099969.1 beta-lactamase JF274247.1.gene1.p01 Protein 2e-44 45
Amir_2178 YP_003099969.1 beta-lactamase FJ214368.1.gene1.p1 Protein 2e-44 45
Amir_2178 YP_003099969.1 beta-lactamase JF274243.1.gene1.p01 Protein 4e-44 45
Amir_2178 YP_003099969.1 beta-lactamase AY029068.1.gene1.p1 Protein 8e-44 45
Amir_2178 YP_003099969.1 beta-lactamase FJ214367.1.gene1.p1 Protein 7e-45 45
Amir_2178 YP_003099969.1 beta-lactamase AY156923.1.gene1.p01 Protein 3e-44 45
Amir_2178 YP_003099969.1 beta-lactamase HQ398215.1.gene1.p01 Protein 5e-44 45
Amir_2178 YP_003099969.1 beta-lactamase FJ907381.1.gene1.p01 Protein 2e-44 45
Amir_2178 YP_003099969.1 beta-lactamase AF325134.1.gene1.p1 Protein 4e-44 45
Amir_2178 YP_003099969.1 beta-lactamase AY847147.1.gene1.p01 Protein 7e-45 45
Amir_2178 YP_003099969.1 beta-lactamase AY033516.1.gene2.p01 Protein 9e-45 45
Amir_2178 YP_003099969.1 beta-lactamase AY822595.1.gene1.p01 Protein 2e-44 45
Amir_2178 YP_003099969.1 beta-lactamase HM803271.1.gene1.p01 Protein 9e-44 45
Amir_2178 YP_003099969.1 beta-lactamase AY847145.1.gene1.p01 Protein 1e-44 45
Amir_2178 YP_003099969.1 beta-lactamase HM755448.1.gene1.p01 Protein 5e-44 45
Amir_2178 YP_003099969.1 beta-lactamase AF252622.2.gene2.p01 Protein 1e-44 45
Amir_2178 YP_003099969.1 beta-lactamase AY847143.1.gene1.p01 Protein 2e-44 45
Amir_2178 YP_003099969.1 beta-lactamase EF418608.1.gene1.p01 Protein 4e-44 45
Amir_2178 YP_003099969.1 beta-lactamase EU136031.3.gene1.p3 Protein 7e-45 45
Amir_2178 YP_003099969.1 beta-lactamase AJ416345.gene.p01 Protein 3e-44 45
Amir_2178 YP_003099969.1 beta-lactamase AF189721.1.gene1.p01 Protein 2e-43 45
Amir_2178 YP_003099969.1 beta-lactamase AY847146.1.gene1.p01 Protein 7e-45 45
Amir_2178 YP_003099969.1 beta-lactamase FJ214366.1.gene1.p1 Protein 1e-44 45
Amir_2178 YP_003099969.1 beta-lactamase AF252623.2.gene1.p01 Protein 3e-44 45
Amir_2178 YP_003099969.1 beta-lactamase AY847144.1.gene1.p01 Protein 9e-45 45
Amir_2178 YP_003099969.1 beta-lactamase JF274246.1.gene1.p01 Protein 3e-44 45
Amir_2178 YP_003099969.1 beta-lactamase HQ833652.1.gene1.p01 Protein 1e-44 45
Amir_2178 YP_003099969.1 beta-lactamase AY143430.1.gene1.p01 Protein 2e-44 45
Amir_2178 YP_003099969.1 beta-lactamase JF274242.1.gene1.p01 Protein 1e-44 45
Amir_2178 YP_003099969.1 beta-lactamase AB205197.1.gene1.p01 Protein 2e-43 44
Amir_2178 YP_003099969.1 beta-lactamase DQ663489.gene.p01 Protein 3e-43 44
Amir_2178 YP_003099969.1 beta-lactamase AY750914.gene.p01 Protein 1e-43 44
Amir_2178 YP_003099969.1 beta-lactamase AY954516.1.gene1.p1 Protein 2e-42 44
Amir_2178 YP_003099969.1 beta-lactamase AY157676.1.gene1.p01 Protein 7e-43 44
Amir_2178 YP_003099969.1 beta-lactamase HQ833651.1.gene1.p01 Protein 8e-44 44
Amir_2178 YP_003099969.1 beta-lactamase HM167760.1.gene1.p01 Protein 3e-42 44
Amir_2178 YP_003099969.1 beta-lactamase AM982522.2.gene1.p01 Protein 1e-42 44
Amir_2178 YP_003099969.1 beta-lactamase DQ211987.1.gene1.p01 Protein 5e-44 44
Amir_2178 YP_003099969.1 beta-lactamase EU545409.1.gene1.p1 Protein 2e-43 44
Amir_2178 YP_003099969.1 beta-lactamase AY005110.1.gene1.p1 Protein 7e-43 44
Amir_2178 YP_003099969.1 beta-lactamase AY303807.gene.p01 Protein 3e-42 43
Amir_2178 YP_003099969.1 beta-lactamase AB284167.2.gene1.p01 Protein 2e-44 43
Amir_2178 YP_003099969.1 beta-lactamase EF374097.1.gene1.p01 Protein 2e-45 43
Amir_2178 YP_003099969.1 beta-lactamase AF518567.2.gene4.p01 Protein 1e-41 43
Amir_2178 YP_003099969.1 beta-lactamase HM776707.1.gene1.p1 Protein 2e-45 43
Amir_2178 YP_003099969.1 beta-lactamase GQ870432.1.gene1.p1 Protein 4e-42 43
Amir_2178 YP_003099969.1 beta-lactamase X92507.1.gene1.p01 Protein 2e-45 43
Amir_2178 YP_003099969.1 beta-lactamase U95364.1.gene1.p01 Protein 9e-45 43
Amir_2178 YP_003099969.1 beta-lactamase AJ567481.1.gene1.p01 Protein 2e-45 43
Amir_2178 YP_003099969.1 beta-lactamase AJ416344.1.gene1.p01 Protein 3e-45 43
Amir_2178 YP_003099969.1 beta-lactamase GQ149243.1.gene1.p01 Protein 8e-45 43
Amir_2178 YP_003099969.1 beta-lactamase DQ023162.1.gene1.p1 Protein 2e-41 43
Amir_2178 YP_003099969.1 beta-lactamase GU127598.1.gene1.p1 Protein 2e-45 43
Amir_2178 YP_003099969.1 beta-lactamase DQ125241.gene.p01 Protein 2e-45 43
Amir_2178 YP_003099969.1 beta-lactamase FJ971899.1.gene1.p1 Protein 4e-42 43
Amir_2178 YP_003099969.1 beta-lactamase GQ149244.1.gene1.p01 Protein 2e-45 43
Amir_2178 YP_003099969.1 beta-lactamase DQ408762.1.gene1.p1 Protein 5e-45 43
Amir_2178 YP_003099969.1 beta-lactamase DQ102702.1.gene1.p1 Protein 2e-44 43
Amir_2178 YP_003099969.1 beta-lactamase DQ328639.gene.p01 Protein 3e-43 43
Amir_2178 YP_003099969.1 beta-lactamase AY034847.1.gene1.p01 Protein 6e-39 42
Amir_2178 YP_003099969.1 beta-lactamase EU729727.1.gene1.p1 Protein 6e-39 42
Amir_2178 YP_003099969.1 beta-lactamase HM066995.1.gene1.p01 Protein 2e-38 42
Amir_2178 YP_003099969.1 beta-lactamase AF395881.gene.p01 Protein 9e-39 42
Amir_2178 YP_003099969.1 beta-lactamase FJ234412.1.gene1.p01 Protein 6e-39 42
Amir_2178 YP_003099969.1 beta-lactamase EU555534.1.gene1.p01 Protein 4e-39 42
Amir_2178 YP_003099969.1 beta-lactamase GQ140348.1.gene1.p01 Protein 2e-38 42
Amir_2178 YP_003099969.1 beta-lactamase AY267213.1.gene1.p01 Protein 3e-44 42
Amir_2178 YP_003099969.1 beta-lactamase X92506.gene.p01 Protein 2e-44 42
Amir_2178 YP_003099969.1 beta-lactamase AY292654.1.gene1.p1 Protein 1e-44 42
Amir_2178 YP_003099969.1 beta-lactamase AJ557142.gene.p01 Protein 4e-44 42
Amir_2178 YP_003099969.1 beta-lactamase DQ256091.1.gene1.p1 Protein 1e-44 42
Amir_2178 YP_003099969.1 beta-lactamase AY649755.1.gene1.p01 Protein 1e-44 42
Amir_2178 YP_003099969.1 beta-lactamase AY238472.1.gene1.p01 Protein 4e-44 42
Amir_2178 YP_003099969.1 beta-lactamase EF219142.1.gene1.p01 Protein 2e-44 42
Amir_2178 YP_003099969.1 beta-lactamase AB177384.1.gene1.p01 Protein 9e-45 42
Amir_2178 YP_003099969.1 beta-lactamase AJ005045.gene.p01 Protein 4e-42 42
Amir_2178 YP_003099969.1 beta-lactamase Y14156.1.gene1.p01 Protein 4e-42 42
Amir_2178 YP_003099969.1 beta-lactamase AY327539.1.gene1.p01 Protein 8e-32 42
Amir_2178 YP_003099969.1 beta-lactamase HM246246.1.gene1.p1 Protein 7e-31 42
Amir_2178 YP_003099969.1 beta-lactamase EU024485.1.gene1.p01 Protein 6e-31 42
Amir_2178 YP_003099969.1 beta-lactamase HQ661363.1.gene1.p1 Protein 5e-31 42
Amir_2178 YP_003099969.1 beta-lactamase EU155018.1.gene1.p01 Protein 4e-31 42
Amir_2178 YP_003099969.1 beta-lactamase AF164577.1.gene1.p01 Protein 6e-31 42
Amir_2178 YP_003099969.1 beta-lactamase EU032604.1.gene1.p01 Protein 5e-31 42
Amir_2178 YP_003099969.1 beta-lactamase AF275256.gene.p01 Protein 1e-40 41
Amir_2178 YP_003099969.1 beta-lactamase HQ641421.1.gene1.p01 Protein 1e-38 41
Amir_2178 YP_003099969.1 beta-lactamase AF297554.1.gene1.p1 Protein 1e-38 41
Amir_2178 YP_003099969.1 beta-lactamase DQ061159.1.gene1.p01 Protein 7e-44 41
Amir_2178 YP_003099969.1 beta-lactamase AY847148.1.gene1.p01 Protein 2e-43 41
Amir_2178 YP_003099969.1 beta-lactamase AF305837.gene.p01 Protein 1e-44 41
Amir_2178 YP_003099969.1 beta-lactamase AF255298.1.gene1.p1 Protein 2e-44 41
Amir_2178 YP_003099969.1 beta-lactamase DQ268764.2.gene6.p01 Protein 2e-44 41
Amir_2178 YP_003099969.1 beta-lactamase DQ810789.1.gene1.p01 Protein 9e-44 41
Amir_2178 YP_003099969.1 beta-lactamase AY080894.1.gene1.p01 Protein 1e-44 41
Amir_2178 YP_003099969.1 beta-lactamase AY995206.gene.p01 Protein 5e-44 41
Amir_2178 YP_003099969.1 beta-lactamase AM411407.1.gene1.p01 Protein 2e-44 41
Amir_2178 YP_003099969.1 beta-lactamase JF966749.1.gene1.p01 Protein 3e-44 41
Amir_2178 YP_003099969.1 beta-lactamase EU402393.1.gene1.p1 Protein 5e-44 41
Amir_2178 YP_003099969.1 beta-lactamase AJ704396.1.gene1.p01 Protein 3e-44 41
Amir_2178 YP_003099969.1 beta-lactamase EF210159.1.gene1.p01 Protein 7e-44 41
Amir_2178 YP_003099969.1 beta-lactamase FJ815436.1.gene1.p01 Protein 2e-43 41
Amir_2178 YP_003099969.1 beta-lactamase FJ873739.1.gene1.p01 Protein 3e-44 41
Amir_2178 YP_003099969.1 beta-lactamase JN227085.1.gene1.p01 Protein 2e-43 41
Amir_2178 YP_003099969.1 beta-lactamase AY598759.gene.p01 Protein 2e-44 41
Amir_2178 YP_003099969.1 beta-lactamase DQ885477.1.gene1.p01 Protein 9e-44 41
Amir_2178 YP_003099969.1 beta-lactamase GQ351346.1.gene1.p01 Protein 5e-44 41
Amir_2178 YP_003099969.1 beta-lactamase Y10278.1.gene1.p01 Protein 2e-44 41
Amir_2178 YP_003099969.1 beta-lactamase EU177100.1.gene1.p01 Protein 2e-44 41
Amir_2178 YP_003099969.1 beta-lactamase AY515297.1.gene1.p1 Protein 8e-44 41
Amir_2178 YP_003099969.1 beta-lactamase EU202673.2.gene1.p2 Protein 2e-44 41
Amir_2178 YP_003099969.1 beta-lactamase EF426798.1.gene1.p1 Protein 8e-44 41
Amir_2178 YP_003099969.1 beta-lactamase AJ549244.1.gene1.p01 Protein 5e-44 41
Amir_2178 YP_003099969.1 beta-lactamase HQ398214.1.gene1.p01 Protein 1e-43 41
Amir_2178 YP_003099969.1 beta-lactamase AF091113.2.gene1.p01 Protein 5e-32 41
Amir_2178 YP_003099969.1 beta-lactamase AM087453.1.gene1.p01 Protein 9e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AJ920369.1.gene1.p01 Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AF367983.gene.p01 Protein 2e-39 41
Amir_2178 YP_003099969.1 beta-lactamase AM176551.2.gene1.p01 Protein 9e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AY528718.1.gene1.p01 Protein 5e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AM176549.2.gene1.p01 Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase DQ193536.1.gene1.p01 Protein 1e-30 41
Amir_2178 YP_003099969.1 beta-lactamase JN051143.1.gene1.p01 Protein 7e-31 41
Amir_2178 YP_003099969.1 beta-lactamase DQ174308.1.gene1.p01 Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AM176555.2.gene1.p01 Protein 9e-31 41
Amir_2178 YP_003099969.1 beta-lactamase HM751100.1.gene1.p01 Protein 3e-31 41
Amir_2178 YP_003099969.1 beta-lactamase DQ322460.1.gene1.p1 Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AF535130.1.gene1.p01 Protein 1e-30 41
Amir_2178 YP_003099969.1 beta-lactamase JX268752.1.gene1.p01 Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AF148850.1.gene1.p01 Protein 9e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AM176550.2.gene1.p01 Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AF208796.2.gene1.p01 Protein 9e-31 41
Amir_2178 YP_003099969.1 beta-lactamase EF373971.1.gene1.p01 Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AB302939.1.gene1.p01 Protein 9e-31 41
Amir_2178 YP_003099969.1 beta-lactamase HQ637576.1.gene1.p01 Protein 9e-31 41
Amir_2178 YP_003099969.1 beta-lactamase EU274581.1.gene1.p1 Protein 5e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AJ866284.2.gene1.p01 Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase HQ661362.1.gene1.p1 Protein 1e-30 41
Amir_2178 YP_003099969.1 beta-lactamase EU418913.1.gene1.p01 Protein 7e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AM176558.2.gene1.p01 Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AM176557.2.gene1.p01 Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AY263404.1.gene1.p1 Protein 1e-30 41
Amir_2178 YP_003099969.1 beta-lactamase DQ013287.1.gene1.p1 Protein 6e-31 41
Amir_2178 YP_003099969.1 beta-lactamase CP000647.1.gene1607. Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AB551737.1.gene1.p01 Protein 9e-31 41
Amir_2178 YP_003099969.1 beta-lactamase DQ836922.1.gene1.p01 Protein 1e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AF227204.1.gene1.p01 Protein 1e-30 41
Amir_2178 YP_003099969.1 beta-lactamase AF467947.1.gene1.p1 Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase FJ668814.gene1.p01 Protein 9e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AF148851.1.gene1.p01 Protein 7e-31 41
Amir_2178 YP_003099969.1 beta-lactamase DQ174305.1.gene1.p01 Protein 9e-31 41
Amir_2178 YP_003099969.1 beta-lactamase JQ029959.1.gene1.p01 Protein 8e-31 41
Amir_2178 YP_003099969.1 beta-lactamase GQ428198.1.gene1.p01 Protein 1e-30 41
Amir_2178 YP_003099969.1 beta-lactamase X98102.1.gene1.p01 Protein 7e-31 41
Amir_2178 YP_003099969.1 beta-lactamase AF299299.1.gene1.p01 Protein 9e-31 41