Gene Information

Name : Amir_0118 (Amir_0118)
Accession : YP_003097935.1
Strain : Actinosynnema mirum DSM 43827
Genome accession: NC_013093
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 125363 - 126613 bp
Length : 1251 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGATCGACCTCAAGGCACTGCGCGAGAACCCGGAAGCCGTTCGTGCGTCCCAGCGGGCGCGGGGCGAGGACGAGTCCCT
GGTCGACGCCCTGCTGTCCGCCGACGAGCGCCGCCGGTCCGCCGTCTCCCGCGCCGACACGCTGCGCGGTGAGCAGAAGG
CGTTCGGCAAGCAGGTCGGCAAGGCCCGCGGTGAGGAGCGCGAGGCGCTGCTCGTCAAGGGCAAGGAGCTGGCCGCCGAG
GTGAAGGCCGCCGAGGCCGACCAGGCCGCCGCCGAGGCCGAGCTGACCGAGCTGCACCGCTCCGTCCCCAACCTCGTGCA
CCCCGACGCCCCCGAGGGCGGCGAGGACGATTACGTCGTGGTCAAGCACGTCGGGGAGCCCCGCGAGTTCGACTTCGAGC
CCCTCGACCACCTCGACCTCGGCACCCGGCTCGGCGCGATCGACATGGAGCGCGGCGCCAAGGTGTCCGGCTCGCGGTTC
TACTTCCTCACCGGCATCGGCGCCCAGCTCGAGCTCGCCCTGCTGAACATGGCCGTCGCCCAGGCGACCGCCGCGGGCTT
CCAGCTCATGATCACCCCGACCCTGGTCCGGCCCGAGGTCATGGCGGGCACCGGGTTCCTCGGCGCGCACTCCAGCGAGA
TCTACCGCCTGGAGGCCGACGACCTCTACCTCGTCGGCACCTCCGAGGTCCCCCTCGCCGGCTACCACGCCGACGAGATC
ATCGACGGCCCGCGCCGCTACGCGGGCTGGTCGTCCTGCTACCGCCGCGAGGCGGGCTCCTACGGCAAGGACACCAGGGG
CATCATCCGGGTGCACCAGTTCAACAAGGTCGAGATGTTCTCCTACGTCCCGCCGGAGGAGGCCGAGGCCGAGCACGCCC
GCCTGCTCGCCTGGGAGGAGGAGATGCTCGCCAAGGTCGAGGTCCCCTACCGGGTGATCGACACCGCCGCGGGCGACCTC
GGCACCAGCGCCTCCCGCAAGTTCGACTGCGAGGCGTGGGTGCCCAGCCAGCAGGCCTACCGCGAGCTCACCTCCACCTC
GAACTGCACCACCTTCCAGGCCCGCAGGCTGAACGTGCGCTACCGCGACGAGAACGGCAAGTCGCAGATCACCGCCACGC
TCAACGGCACCCTGGCCACCACCCGCTGGATCGTCGCCATCCTGGAGAACCACCAGCAGGCCGACGGCTCCGTCGTCGTC
CCGCAGGCGCTGCGCCCGTTCCTGGGCAAGGACGTCCTCCTCCCGGCCTGA

Protein sequence :
MIDLKALRENPEAVRASQRARGEDESLVDALLSADERRRSAVSRADTLRGEQKAFGKQVGKARGEEREALLVKGKELAAE
VKAAEADQAAAEAELTELHRSVPNLVHPDAPEGGEDDYVVVKHVGEPREFDFEPLDHLDLGTRLGAIDMERGAKVSGSRF
YFLTGIGAQLELALLNMAVAQATAAGFQLMITPTLVRPEVMAGTGFLGAHSSEIYRLEADDLYLVGTSEVPLAGYHADEI
IDGPRRYAGWSSCYRREAGSYGKDTRGIIRVHQFNKVEMFSYVPPEEAEAEHARLLAWEEEMLAKVEVPYRVIDTAAGDL
GTSASRKFDCEAWVPSQQAYRELTSTSNCTTFQARRLNVRYRDENGKSQITATLNGTLATTRWIVAILENHQQADGSVVV
PQALRPFLGKDVLLPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-63 43