Gene Information

Name : Amir_1089 (Amir_1089)
Accession : YP_003098891.1
Strain : Actinosynnema mirum DSM 43827
Genome accession: NC_013093
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 1210449 - 1211972 bp
Length : 1524 bp
Strand : +
Note : PFAM: Aldehyde Dehydrogenase; KEGG: mxa:MXAN_5040 aldehyde dehydrogenase family protein

DNA sequence :
ATGGCGAAGTACGCGGCACCGGGGCAACCGGACAGCGTGGTGAGCTACCGGAGCAGGTACGACCACTTCATCGGCGGCGA
GTTCACCGCCCCGGCGAAGGGCGGCTACTTCGAGAACCCCACCCCGGTCACCGGTGAGACGTTCACCGAGGTCGCCAGGG
GCACGGCCGAGGACGTCGAGCGCGCCCTCGACGCCGCCCACGGCGCCGCGCCCGCGTGGGGCCGCACCTCGCCCGCCGAG
CGCGCCAACGTCCTCAACAAGATCGCGGACCGGATCGAGGCCAACCTGGAGGCCCTCGCCGTCGCCGAGACCTGGGACAA
CGGCAAGGCGGTGCGCGAGACGCTGGCGGCCGACCTGCCGCTGGCCGTCGACCACTTCCGCTACTTCGCGGGCGCCCTGC
GCGCCCAGGAGGGCGGCATCTCGCAGATCGACGAGAACCTCGTCGCCTACCACTTCCACGAGCCGCTCGGCGTGGTCGGC
CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCCGTGTGGAAGCTCGCCCCCGCGCTCGCGGCGGGCAACGCGGTCGT
GCTCAAGCCCGCCGAGCAGACCCCCGCGTCGATCATGGTGCTGGTCGAGCTGATCGCCGACCTGCTGCCGCCGGGCGTGC
TGAACGTGGTCAACGGCTTCGGCGTGGAGGCGGGCAAGCCGCTGGCCACCAGCAAGCGCGTCGCGAAGGTCGCGTTCACC
GGTGAGACCACCACCGGCAGGCTGATCATGCAGTACGCCAGCGAGAACATCATCCCGGTCACCCTGGAGCTGGGCGGCAA
GAGCCCGAACATCTTCTTCGGCGACGTGGCGGCCCAGCGCGACGAGTTCTACGACAAGGCCCTCGAGGGCTTCACGATGT
TCGCGCTCAACCAGGGCGAGGTGTGCACCTGCCCGTCCCGCGCGCTGATCCAGGGCTCGATCTACGAGCAGTTCCTCGGC
GACGCGGTCGAGCGCACCAAGGCGGTCAAGCAGGGCCACCCGCTCGACACCGACACGATGATCGGCGCGCAGGCCAGCAA
CGACCAGCTGGAGAAGATCCTCGCCTACATCGAGATCGGCAAGGCCGAGGGCGCCACGCTGCTCACCGGCGGCGGTCGCG
CGGACCTGGGCGGCGAGCTGTCCGGCGGCTACTACGTCACCCCGACCGTGTTCGAGGGCGACAACAAGATGCGGATCTTC
CAGGAGGAGATCTTCGGCCCGGTCGTGTCGGTCGCCCGCTTCGACGACTACGCCGACGCCATCAAGATCGCCAACGACAC
GCTGTACGGCCTCGGCGCGGGCGTCTGGTCCCGCGACGGGTCCACCGCCTACCGCGCGGGCCGCGAGATCCAGGCGGGCC
GGGTGTGGGTGAACAACTACCACACCTACCCGGCGCACGCGGCGTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGCGAG
AACCACCGGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTGGTCAGCTACGCCCCCGGCGCGCAGGGCTTCTT
CTGA

Protein sequence :
MAKYAAPGQPDSVVSYRSRYDHFIGGEFTAPAKGGYFENPTPVTGETFTEVARGTAEDVERALDAAHGAAPAWGRTSPAE
RANVLNKIADRIEANLEALAVAETWDNGKAVRETLAADLPLAVDHFRYFAGALRAQEGGISQIDENLVAYHFHEPLGVVG
QIIPWNFPILMAVWKLAPALAAGNAVVLKPAEQTPASIMVLVELIADLLPPGVLNVVNGFGVEAGKPLATSKRVAKVAFT
GETTTGRLIMQYASENIIPVTLELGGKSPNIFFGDVAAQRDEFYDKALEGFTMFALNQGEVCTCPSRALIQGSIYEQFLG
DAVERTKAVKQGHPLDTDTMIGAQASNDQLEKILAYIEIGKAEGATLLTGGGRADLGGELSGGYYVTPTVFEGDNKMRIF
QEEIFGPVVSVARFDDYADAIKIANDTLYGLGAGVWSRDGSTAYRAGREIQAGRVWVNNYHTYPAHAAFGGYKQSGIGRE
NHRMMLDHYQQTKNLLVSYAPGAQGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-150 61
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 8e-156 59
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 8e-156 59
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 8e-156 59
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-155 59
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-71 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Amir_1089 YP_003098891.1 aldehyde dehydrogenase VFG0082 Protein 2e-150 61