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Name : leuS (FIC_00413) Accession : YP_003094942.1 Strain : Flavobacteriaceae bacterium 3519-10 Genome accession: NC_013062 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 421779 - 424592 bp Length : 2814 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGTTCTACGACCATCAATCGATCGAAAAAAAGTGGCAGAAATTCTGGAAAGAAAACCAGACTTTTAAAACTGAAGACAA CACCCAAAAGCCTAAATATTACGTCCTCGATATGTTTCCGTATCCTTCGGGAGCCGGTCTGCACGTCGGGCATCCACTGG GCTACATTGCATCGGATATTTATGCAAGGTATAAAAGACATGAGGGTTACAACGTGCTTCATCCGGTAGGTTACGACAGC TTTGGGCTTCCGGCGGAGCAGTATGCCATTCAAACCGGCACACATCCCGCGATTACTACAGAACAGAACATCACAAGATA TGAAGAACAGCTTCGGAAGATTGGTTTTTCGTTCGACTGGAGCCGCGAAGTAAGGACTTCCGATTCCTCTTATTATAAGT GGACACAATGGATTTTTATTGAACTTTTCAATTCGTGGTACAATAAAGCTGAAGATAAAGCTGAGCCCATTACAACTCTG ATTGAATATTTTGCAAAAAATGGCTCCGCAGAATTGTCAGCTGCGCAGAATGATGAACTGAATTTTTCTGCAGAAGAATG GAATAATGCTTGCGAACTTGATCAGCAGGATATTCTTTTGAACTACCGCCTGGCTTTTCGCGCTGAAACTACCGTAAACT GGTGCCCGGGATTAGGAACAGTTCTGGCAAATGATGAAGTGAAAGACGGTAAATCCGAACGTGGCGGCTTCCCTGTATTT CAAAAGAAAATGATGCAGTGGAGTATGCGGATCACCGCTTATTCCGAAAGATTGCTGCAGGGATTACAGAATATCGACTG GCCACAGCCGCTGAAAGATGCTCAGGAATACTGGATCGGCAAATCGCAGGGTGCACAGGTCACTTTCGGTTTAGATAATG GTACTGAGCAGATTACTGTTTTCACAACGCGGCCTGACACGATCTTCGGCGCCACATTTATGGTTTTGGCTCCCGAAAAT CCGTTAGTTGAGACGATAACTACTCCTAATCAAAAGGAGGAAGTTGAAAATTATATTCAGGAAACTTCCAAAAAAACAGA GCGCGACCGCATGGCCGACGTTAAAAACGTGAGTGGAGCTTTCACCGGAGCTTATGCGGTAAACCCGTTCACGCATGAGA AAATGCCGGTTTATATTTCAGATTATGTACTGATGGGTTACGGTACCGGTGCTGTAATGGCTGTTCCGGCGCATGACGAA CGCGATCATCGTTTTGCAAAAAAGTTCGCTTTACCGATCTTAAATGTCATTAAAAACGATGAAGATATCAACGAAACTTC GTACGATTCGAAGAACTCGGTGTGTGTAAACTCTGGTTTTTTAGATGGTTTAAATTATACAGAAGCTAAAGCAAAGATTA TCTCAGAAATTGAAAAGCTCGGTATTGGCCGTGGAACAACGAACTACCGCCAACGCGATGCTATTTTCTCGCGCCAAAGA TATTGGGGCGAACCCGTTCCGGTGTATTATAAAGATGGGATGCCTTATCCGCTGCCGGTTTCAGCGCTTCCATTGGAACT TCCGGAAGTTGAAAAATATTTACCAACCGAAGACGGAGACCCACCATTAGGAAATGCAAAAAATTTCGGTTGGGACGAAA AGAACGAAAAGGTTGTTGCTACAGAACTGATTGATGAAAAGTCGGTTTTCGCGCTCGAATTATCAACAATGCCGGGCTGG GCCGGAAGTTCATGGTATTTTTTAAGATACATGGATCCGCATAACGATGAGGTTTTTGCACAAAAAGAGCTCACCGATTA TTGGGGCCAGGTTGATTTATACATTGGCGGAAGCGAACACGCTACCGGACATTTATTGTATTCAAGATTCTGGAATATGT TCTTGAAAGACCGCGGTTACGTTCAACATGATGAACCTTTCAAAAAACTGATAAATCAGGGAATGATTTTGGGGATGAGC GCGTATGTTTTCAGAATTGAAGGTACCAACCAGTTTATTTCAAAGAATTTAATTCAGGACCATACCACTCAAAAAATTCA TGTGGACGTTTCTTTATTAAAAGGAACTTCGGATGAACTGGATATCGAAAGATTCAAAAACTGGCGTTCCGAATATGCTG ATGCCGAATTTATTCTTGAAGACGGAAAATATATCACGGAAAGAGAAGTGGAAAAAATGTCCAAGTCCAAATACAATGTC GTGAATCCCGATGACATCTGTGAAGAATACGGCGCGGACTGTCTTCGTTTATACGAGATGTTCTTAGGGCCACTTGAACA GTCGAAGCCATGGAACACGCAGGGCCTCAGTGGCGTTTATGGTTTTCTGAAGAAATTCTATAATCTGTATTTTAACGGAG ACCAGTTCGAAGTTTCCGATGAAGAGCCGACAAAAGAGGAATATAAGATTCTGCATACGTTGATCAGAAAGGTGGTTTCG GATATTGCCAATTTCTCGTTCAATACTTCAGTTTCTTCTTTTATGATCGCGGTGAACGAGTACCAAAAGCTCAAAACCAA CAAACGCCAAATTCTGGAGGCAATGGCGGTGATTGTTTCGCCATATGCGCCGCACCTGTGCGAAGAACTTTGGAGCAGGC TTGGGCACAACAGTACGGTTGAGTTAGAAAAGTTCCCGGAATTCGATGAAAAATATCTGGTAGAAGACGAATTTGAGTAC CCTGTGAGTTTTAACGGAAAGATGAGATTTAAACTTTCACTGCCGGCAGATTATACGGTTTCAGAGATTGAAGAAAGTGT GATGAAAGACCAGCGTGTAATAAATCAGCTGGCCGGAAATAGTCCTAAAAAAATCATTATAGTACAGAAAAAAATCATTA ATATTGTCTCATAA Protein sequence : MFYDHQSIEKKWQKFWKENQTFKTEDNTQKPKYYVLDMFPYPSGAGLHVGHPLGYIASDIYARYKRHEGYNVLHPVGYDS FGLPAEQYAIQTGTHPAITTEQNITRYEEQLRKIGFSFDWSREVRTSDSSYYKWTQWIFIELFNSWYNKAEDKAEPITTL IEYFAKNGSAELSAAQNDELNFSAEEWNNACELDQQDILLNYRLAFRAETTVNWCPGLGTVLANDEVKDGKSERGGFPVF QKKMMQWSMRITAYSERLLQGLQNIDWPQPLKDAQEYWIGKSQGAQVTFGLDNGTEQITVFTTRPDTIFGATFMVLAPEN PLVETITTPNQKEEVENYIQETSKKTERDRMADVKNVSGAFTGAYAVNPFTHEKMPVYISDYVLMGYGTGAVMAVPAHDE RDHRFAKKFALPILNVIKNDEDINETSYDSKNSVCVNSGFLDGLNYTEAKAKIISEIEKLGIGRGTTNYRQRDAIFSRQR YWGEPVPVYYKDGMPYPLPVSALPLELPEVEKYLPTEDGDPPLGNAKNFGWDEKNEKVVATELIDEKSVFALELSTMPGW AGSSWYFLRYMDPHNDEVFAQKELTDYWGQVDLYIGGSEHATGHLLYSRFWNMFLKDRGYVQHDEPFKKLINQGMILGMS AYVFRIEGTNQFISKNLIQDHTTQKIHVDVSLLKGTSDELDIERFKNWRSEYADAEFILEDGKYITEREVEKMSKSKYNV VNPDDICEEYGADCLRLYEMFLGPLEQSKPWNTQGLSGVYGFLKKFYNLYFNGDQFEVSDEEPTKEEYKILHTLIRKVVS DIANFSFNTSVSSFMIAVNEYQKLKTNKRQILEAMAVIVSPYAPHLCEELWSRLGHNSTVELEKFPEFDEKYLVEDEFEY PVSFNGKMRFKLSLPADYTVSEIEESVMKDQRVINQLAGNSPKKIIIVQKKIINIVS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 7e-131 | 42 |
