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Name : lysS (FIC_01499) Accession : YP_003096008.1 Strain : Flavobacteriaceae bacterium 3519-10 Genome accession: NC_013062 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 1616580 - 1618277 bp Length : 1698 bp Strand : + Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGCAGTTATCAGAACAGGAAATCATCAGAAGAGAAAAGTTGCAGACCCTGCAAAAAATGGGCATCAATGCTTTTCCGGC GGAAGAATATACAATTACACATACCACAAAAGCGATTAAAGAAAGCTTCGCCGAAGGCGAAAAAGTGCAGATTGCCGGCC GACTGATGAGCCGCAGGATCCAAGGAAAGGCAAGTTTTGCCGAACTTCAGGATTCTGACGGAAGAATTCAGGTGTATTTC AACCGCGACGAGATCTGTACCGGTGACGATAAAACACTGTATAACGAAGTTTATAAACATTTGCTCGACATCGGCGATAT TATAGGCATCGAAGGCGAACTATTTACCACTCAGGTCGGCGAAATGACTGTGAAAGTTGAGAACTTTAAAATTTTAACCA AATCGCTCCGCCCGCTGCCGCAGCCAAGGACAGACGAAAACGGCGTTACGCACGATGCTTTCAACGATCCGGAACTTAGA TACAGACAACGTTATGTTGATTTAATTGTGAATCCGCAGGTGAAAGATGTCTTCGTGAAACGCACGAAACTTTTCAACGC GATGCGCACATTTTTCAATGATGCAGGTTATTTTGAAGTGGAGACGCCAATCTTGCAATCGATTCCGGGTGGCGCGGCAG CTAAACCTTTTATCACCCATCACAATGCGCTCGACATTCCGCTCTATTTAAGAATTGCGAACGAACTTTATCTGAAAAGA CTTATCGTTGGCGGTTTCGACGGGGTGTACGAATTCTCCAAAAACTTCAGAAATGAAGGGATGGACAGAACCCACAACCC GGAGTTTACGGCTCTTGAGATCTATGTGGCCTACAAAGATTATAACTGGATGATGGATTTCACTGAAAAACTGCTCGAAT ACTGTGCAGTTCAGGTAAACGGAAGCACAAACGCCACTTTTGGTGAGCATCAGATTGATTTTAAAGCGCCGTATCCACGA ATTTCGATGACTGAAGCAATCCTGAATTTCACGGGATTTGATATCACCGGAAAATCTGAAAGCGAACTTTTCGATTTTGC AAAATCGATCGGTATCGACGTGAATGAAACGATGGGCAAAGGAAAACTGATCGACGAAATATTCGGCGAAAAATGTGAAG GAAACTTTATTCAGCCTACATTTATCACCGATTATCCGATTGAGATGTCACCTTTAACCAAAAAACACCGAAGCAAGGAA GGTTTAACCGAGCGTTTTGAGCTGATGGTTTGTGGTAAAGAAGTCGCGAATGCCTATTCGGAGTTGAATGATCCGATTGA CCAACGTGAGCGCTTCGAAGCGCAGGCAGCACTTTCGGAAAGAGGAGATGACGAAGCGATGTTTATCGACAACGATTTCC TCCGCGCACTTGAATACGGAATGCCGCCAACATCTGGTTTGGGAATTGGAATGGACCGTTTGATTATGTTCCTCACGAAC AATCCGTCGATCCAGGAAATATTGTTTTTCCCACAGATGAAACCGGAAAAAACTATTCCGCAGATTGAGCTCGGCGAAGA CGAGAAAGCAATTCTTGAAATATTAAACTCACAGGAAGAAGCATTTTTACTGAATGAACTTAAAGAAAGAAGTCAGCTTT CTGGAAAAAAATGGGATAAAGCCACGAAAAATCTCACTAAATTCGAGATGATAAAAGTGACAAAAACGGACGAAAACGTT TTCGTGAATCTGATCTGA Protein sequence : MQLSEQEIIRREKLQTLQKMGINAFPAEEYTITHTTKAIKESFAEGEKVQIAGRLMSRRIQGKASFAELQDSDGRIQVYF NRDEICTGDDKTLYNEVYKHLLDIGDIIGIEGELFTTQVGEMTVKVENFKILTKSLRPLPQPRTDENGVTHDAFNDPELR YRQRYVDLIVNPQVKDVFVKRTKLFNAMRTFFNDAGYFEVETPILQSIPGGAAAKPFITHHNALDIPLYLRIANELYLKR LIVGGFDGVYEFSKNFRNEGMDRTHNPEFTALEIYVAYKDYNWMMDFTEKLLEYCAVQVNGSTNATFGEHQIDFKAPYPR ISMTEAILNFTGFDITGKSESELFDFAKSIGIDVNETMGKGKLIDEIFGEKCEGNFIQPTFITDYPIEMSPLTKKHRSKE GLTERFELMVCGKEVANAYSELNDPIDQRERFEAQAALSERGDDEAMFIDNDFLRALEYGMPPTSGLGIGMDRLIMFLTN NPSIQEILFFPQMKPEKTIPQIELGEDEKAILEILNSQEEAFLLNELKERSQLSGKKWDKATKNLTKFEMIKVTKTDENV FVNLI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 6e-95 | 44 |
| lysS | YP_005163386.1 | lysyl-tRNA synthetase | Not tested | Not named | Protein | 6e-77 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_003096008.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 3e-95 | 44 |
