Gene Information

Name : FIC_00139 (FIC_00139)
Accession : YP_003094676.1
Strain : Flavobacteriaceae bacterium 3519-10
Genome accession: NC_013062
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 131601 - 132869 bp
Length : 1269 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTACAGGTTAATTTTTTGCGCGAAGAACGCGAGCGTGTTTTAGAAGGTTTAAATAAACGGAATTTCCGGCAGATTTC
TTTGGTTGACGAAGCCATTGAAACTGATGACGAAAGAAAGAAATTTCAGACCGAACTTGACCAGAATTTGTCGGAGATGA
ATAAAATTTCGAAAGAAATCGGCATCCTGATGAAAGAAGGCAGGAAAGACGAGGCCGAGACCGCGAAATCTAAAACCGCT
GCATTTAAAGAAAATGTTCAGAATCTCCAGCAGCAGCTGAAAGATGCCGAAGCAAAGCTTCTTGAAATTCTATACCAGAT
TCCGAATATCCCAAACACAAAAGTTGTTGCCGGTACCGCTGCCGAGGATAACGAAATTGTTTACCAGTCGCATGATGTGG
AAGGTTTGGGCGAAGGCGCAATTCCACACTGGGAACTCGCCAAAAAGTATAATTTAATAGATTTTGAACTCGGGGTGAAA
GTTGCAGGTGCCGGTTTTCCGGTGTATTTTGGCAAAGGCGCGCGATTACAGCGGTCTTTGGTGCAATACTTTTTAGATAA
AAATACCGATGCCGGTTATCTTGAGGTTAATCCGCCACATGTTGTAAACGAAGCTTCGGGTTACGGTACCGGGCAGCTGC
CGGATAAAGAGGGACAGATGTATTACGCTCCCGAAGATAAACTGTACCTGATCCCGACAGCAGAAGTTCCGGTTACAAAC
CTTTACCGTGATGTTTTGTTGGAAGAGCGCGAACTGCCGATTAAAAACACCGCTTTTTCGCAGTGCTACCGCCGCGAAGC
CGGAAGTTATGGCGCGCATGTTCGGGGCCTCAACAGGCTTCATCAATTCGAAAAGGTAGAAATAGTAAGGCTTGAAAAAC
CCGAAAATTCGTACGCTGCGCTCGATGAGATGGTAGAACACGTGAAGACTCTTCTTACGGAACTGGAATTACCGTTCCGC
ATCTTGCGTCTTTGCGGTGGCGATATGGGTTTCACGTCGTCGATGACTTACGATTTTGAAGTGTGGAGTGCCGCACAGGA
AAAATGGCTCGAAGTTTCTTCAGTTTCAAATTTTGAGACTTTCCAGGCAAACAGATTGAAATGCAGGTTCAGAACCGATG
GAAAGACTCAGTTAGTCCACACCCTGAATGGTTCAGCACTTGCGCTGCCGAGAATTATGGCGGCTCTTTTAGAAAATAAC
CAAACGGCGGACGGCATTAAGATTCCGGCAAAAATTGCGGAATACACCAAGTTCGACTTGATTAGCTAA

Protein sequence :
MLQVNFLREERERVLEGLNKRNFRQISLVDEAIETDDERKKFQTELDQNLSEMNKISKEIGILMKEGRKDEAETAKSKTA
AFKENVQNLQQQLKDAEAKLLEILYQIPNIPNTKVVAGTAAEDNEIVYQSHDVEGLGEGAIPHWELAKKYNLIDFELGVK
VAGAGFPVYFGKGARLQRSLVQYFLDKNTDAGYLEVNPPHVVNEASGYGTGQLPDKEGQMYYAPEDKLYLIPTAEVPVTN
LYRDVLLEERELPIKNTAFSQCYRREAGSYGAHVRGLNRLHQFEKVEIVRLEKPENSYAALDEMVEHVKTLLTELELPFR
ILRLCGGDMGFTSSMTYDFEVWSAAQEKWLEVSSVSNFETFQANRLKCRFRTDGKTQLVHTLNGSALALPRIMAALLENN
QTADGIKIPAKIAEYTKFDLIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-66 41