Gene Information

Name : Phep_4190 (Phep_4190)
Accession : YP_003094443.1
Strain : Pedobacter heparinus DSM 2366
Genome accession: NC_013061
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 5069453 - 5070883 bp
Length : 1431 bp
Strand : -
Note : PFAM: Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGAAACCATTTCATTCTAGAACAAAAATCGTAGCCACTTTAGGCCCCGCCTCAGCTAAACCAGACGTTTTATATAGTAT
GTTTAATGCCGGACTGGATGTTTGCCGTTTAAACTTTTCTCATGGTTCACAGGCAGATCACCAGGAGGTATTGGATACCA
TTCGTGGCCTTAATGAAAAACACAATTATAATGTTGGGATCCTTGCTGATCTTCAAGGGCCGAAAATAAGGATTGGTATG
GTGAAGGACGGTGGTATTCAGCTGGTTAATGGAGCGAAAACCATTATTACCACTAAGGAGTGCATTGGCAACGAAGAACG
CATTTACATCACTTATGAGTCTTTTCCGAAAGATGTTAAAGCTGGCGAGATCATCTTATTGGATGACGGTAAACTACAGA
TGCGGGTATTGGAAACAAATCATCAAGATGAAGTTGTTTGCGAGATTGTTCATGGTGGGATACTAACTTCCAGGAAAGGT
GTGAACCTGCCAAATACCAAAGTTTCTATTCCATCGCTTACAATAGAAGACCGTAAAAACCTTGAATTTGTTCTCGAAAA
CGATGTAGAATGGATCGGGCTTTCTTTTGTACGAAATGCTGAAGACATCATAGAATTAAAGGATATCATTAAAGAACGCG
GAAAATCAGCCCGTGTGATTGCAAAAATTGAGAAACCGGAAGCGATTGCAAATATTGATGAAATTATTGCTGTTTCTGAC
GGGATTATGGTTGCACGTGGTGATCTGGGCGTTGAAATGCCAATGGAAGAAGTGCCTTTGCTGCAAAAAATGATTGTTCA
GAAATGTCGTGCTGCTTCAAAACCTGTAATTGTGGCCACACAGATGCTGGAAAGTATGATCACGACACCAAGACCAACAC
GTGCCGAGGTAAATGACGTAGCCAATTCAGTATTGGATGGGGCAGATGCAGTAATGCTGAGCGGGGAAACCTCTGTAGGT
GAGTTTCCGTTGATCGTTATTGAAACCATGCAAAAGATCATTCAGAACATCGAGCAAAACAATTATCCTTTTCATCCTGA
GAAATTCCTTAAGCCTAAAGCAGAGAGCTTTTTAAGTGATGCAGTTTGCGATACTGCCTGCTTCCTGTCAAAACAAACCA
ATGCAGTTGGTATTGTTTCGATGACACTGAGTGGCTATACCGCTTTTGAGATCTCGAGTCACAGGCCAAAAGCCCACGTT
TACATTTTTACAAGTAACAGAAGCCTGTTAAACAGTCTGAGTTTACTTTGGGGGGTTCAGGGCTTCTTTTATGACAGGTT
TGAGAGCACTGATGAAACCATACAGGATGTGAATGATTTGCTCAAAGCGAATAAACTGATCAAAAGCGGTGATGTGATTA
TCAACACAGCGGCTATCCCGATGGAGCGTAAGGGCAAAACGAATATGCTAAAAGTTACGGTTATTGATTAA

Protein sequence :
MKPFHSRTKIVATLGPASAKPDVLYSMFNAGLDVCRLNFSHGSQADHQEVLDTIRGLNEKHNYNVGILADLQGPKIRIGM
VKDGGIQLVNGAKTIITTKECIGNEERIYITYESFPKDVKAGEIILLDDGKLQMRVLETNHQDEVVCEIVHGGILTSRKG
VNLPNTKVSIPSLTIEDRKNLEFVLENDVEWIGLSFVRNAEDIIELKDIIKERGKSARVIAKIEKPEAIANIDEIIAVSD
GIMVARGDLGVEMPMEEVPLLQKMIVQKCRAASKPVIVATQMLESMITTPRPTRAEVNDVANSVLDGADAVMLSGETSVG
EFPLIVIETMQKIIQNIEQNNYPFHPEKFLKPKAESFLSDAVCDTACFLSKQTNAVGIVSMTLSGYTAFEISSHRPKAHV
YIFTSNRSLLNSLSLLWGVQGFFYDRFESTDETIQDVNDLLKANKLIKSGDVIINTAAIPMERKGKTNMLKVTVID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-61 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-61 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-61 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 7e-61 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Phep_4190 YP_003094443.1 pyruvate kinase VFG0479 Protein 8e-62 44