Gene Information

Name : Phep_3952 (Phep_3952)
Accession : YP_003094205.1
Strain : Pedobacter heparinus DSM 2366
Genome accession: NC_013061
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 4753073 - 4754347 bp
Length : 1275 bp
Strand : +
Note : PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; TIGRFAM: nucleotide sugar dehydrogenase

DNA sequence :
ATGTCAGCAGCAAATAAGCCACATATTGCAATTATCGGATTAGGCTATGTAGGGCTACCCCTGGCCATTGAATTTGCCAA
ACAGTACCAGGTATTGGGCTTTGATATTGATGAAGAAAGAATAAAAGACCTTACTGCAAACATAGACCGCACCAAAGAGG
CAGACCTGAACGCACTACAAAATGTACTTGGTAAAGGTCTTACCCTATCCTCCAATCAATCCTTATTAGAAGACTGCAAT
GTTTACATCGTAACGGTACCTACCCCTATTGATCAGTTTAAGGCGCCCGACTTAAAACCCTTGCTTAGTGCTTCTAAAAT
GCTGGCAAAGTACCTGTTAAAAGGAGATGTGGTCATTTATGAATCTACCGTTTACCCGGGCTGTACCGAAGAGGATTGCG
TACCCATCCTGGAAAAACACTCCGGTTTAAAATACAATAGCGATTTTTATTGCGGCTATTCCCCGGAAAGGATCAACCCT
GGCGACAAAGTAAACACGCTTACCAAAATCATCAAGGTTACTTCTGGTTCTACTCCCGAAGTGGCCGACTGGATTGACGG
ACTATACGCCAGCATCATTACCGCAGGTACCCACAAAGCCCCAAGCATAAAAGTTGCTGAGGCCTCAAAAGCCATAGAAA
ATGCCCAGCGGGATGTAAATATCTCCTTTGTGAACGAACTGGCACTTATATTCGATAAGCTGGATATTGATACTGCAGAC
GTGATTGCAGCTGCAGGAACAAAATGGAATTTCCTGAAATATAAGCCTGGCCTGGTGGGTGGGCACTGCATTGGGGTCGA
TCCCTATTACCTGGCACATAAATCCAATGCACTTGGTTACACCCCTCAGGTCATCCTGTCGGGCAGAAGGGTGAACGAAA
ACATGGGTATTTTTGTGGCCAGTAAGGTGGTTAAAATGATGATTGCCAAAGGATCTGCTGTAAAAGGAGAAAAAGCCCTC
ATTCTGGGTTTCGCATTTAAAGAAAACTGTCCGGACATCAGGAACACCAGGGTTATCGATATTTATACAGAGTTGCAGCA
ATTTGGTATGGAAGTAGATGTTTATGATCCATGGGCAAATGCAGATGAAGTAGCGCAGGAATATAACATTACATTAAGCC
CAGACCTGGCAAACCAGGAATATAAAGCAATCATCATTGCCGTTGCCCATAATGAGTTTTTGAGCATCGATTACCAGAAA
TACAAACAAGCGGGCGCAATCATTTTTGATACCAAATCATTTATCGACCGCAAGTTTGCAGATGCAAGATTGTAA

Protein sequence :
MSAANKPHIAIIGLGYVGLPLAIEFAKQYQVLGFDIDEERIKDLTANIDRTKEADLNALQNVLGKGLTLSSNQSLLEDCN
VYIVTVPTPIDQFKAPDLKPLLSASKMLAKYLLKGDVVIYESTVYPGCTEEDCVPILEKHSGLKYNSDFYCGYSPERINP
GDKVNTLTKIIKVTSGSTPEVADWIDGLYASIITAGTHKAPSIKVAEASKAIENAQRDVNISFVNELALIFDKLDIDTAD
VIAAAGTKWNFLKYKPGLVGGHCIGVDPYYLAHKSNALGYTPQVILSGRRVNENMGIFVASKVVKMMIAKGSAVKGEKAL
ILGFAFKENCPDIRNTRVIDIYTELQQFGMEVDVYDPWANADEVAQEYNITLSPDLANQEYKAIIIAVAHNEFLSIDYQK
YKQAGAIIFDTKSFIDRKFADARL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 3e-114 54
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 3e-114 54
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-101 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Phep_3952 YP_003094205.1 nucleotide sugar dehydrogenase VFG0431 Protein 1e-114 54