Gene Information

Name : leuS (Phep_3538)
Accession : YP_003093791.1
Strain : Pedobacter heparinus DSM 2366
Genome accession: NC_013061
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 4209456 - 4212266 bp
Length : 2811 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGATTACCAATTTAAAGAGATAGAACAAAAGTGGCAGAAATTCTGGGCGCAGCATAAAACATTTAAGGCAGCTGATGC
CAGTAATAAACCTAAGTTTTATGTATTGGATATGTTTCCTTACCCCTCCGGGGCCGGGTTACATGTTGGTCATCCGCTGG
GATATATTGCCTCCGATATCTTTTCAAGATATAAAAGGTTAAAGGGCTTTAATGTGCTGCATCCCATGGGCTATGATTCT
TTTGGGTTGCCGGCCGAACAGTATGCAATACAGACCGGGCAGCATCCTGCATTAACAACCGAAGCCAATATCAATACTTA
CCGTAAACAGCTGGATGGGCTTGGATTTTCTTTCGACTGGAGCAGGGAAGTGCGTACCAGTGATCCGGAATATTATAAAT
GGACACAGTGGATTTTTATGCAATTGTTTAACTCCTGGTATAACCTGGAAACGGACAGGGCAGAAGATATAACCACGCTG
ATAGAAAAATTTAATGCCTCGGGCAGTGCCGACGTAAAAGCCGTTTGTGATGAAGACACAAAGACCTTTATGCCGAGCGA
CTGGGCTGTTATGACTGATGAGGAAAAACAGGAAGAACTGTTAAAATACCGACTCACTTATTTAAAGGAAAGCACTGTAA
ACTGGTGTGCTGCATTGGGTACAGTGCTGGCCAATGACGAAGTAAAAGATGGTTTTTCTGAGCGTGGAGGGCATCCGGTA
GAACAGAAAAAGATGATGCAATGGAGCATGCGGATCTCTGCTTATGCAGAGCGTTTGCTGCAGGGTTTAAATACGATAGA
CTGGCCTGAGCCGGTTAAAGAGATGCAGCGCAACTGGATAGGTAAAAGTATCGGTGCCGCTGTGAAGTTTAAAATTGAAG
CTGCAGTCAGCAAAGCATTGCCTGCTGGTGTAGATGCCATTGAAGTTTTTACTACCCGCGTAGATACCATTTTCGGAGTT
TCGTACCTGGTACTGGCGCCTGAACATGAGCTGGTGACGGCCTTAACTACGCCCGGACAACTTGATGCGGTGAACAGTTA
TATCGCCCAGACCAAAAAGAAATCTGAACTGGACCGTATGGCCGATACCAAAACCGTATCGGGTGCTTTTACAGGAAGTT
ATGTGATTAACCCGGTAAGCGGTGAGCGCATCCAGCTGTGGATTGCCGATTATGTGCTTGCTGGTTATGGAACCGGTGCG
GTAATGGGTGTGCCGAGCGGCGACCAGCGCGACTGGTTGTTTGCTACGCATTTTAACCTGCCAATTGTGCAGATCCTGGA
TGCACAACAGGATATTGAGCATCAGGCCGATGCTACTAAAGACGGAAAATACATCAATTCCGGTTTCATTAACGGAATGA
ATTATACGGAGGCTACGGCTACTTTAAATGCCTGGCTGGAAGAGCAGGGGCAAGGTAAAGCGAAAATAAATTACCGCATG
CGCGACGCGATATTTGGTCGCCAGCGCTATTGGGGCGAGCCAATCCCGGTATATTTTAAAGATGGCCTGCCCTATTTAAT
TAAAGCAGAAGAATTGCCTTTACTGCTGCCCGAAATTGATAAGTATTTGCCTACAGAGACAGGCGAGCCGCCATTGGGCA
GAGCTGAGGACTGGAAATATGAGGATGAATACGAGTACGAGCTGAGCACCATGCCTGGCTGGGCTGGTTCCAGCTGGTAT
TGGTACCGTTATATGGATGCAAAAAATGATTCGGATTTTGCTTCAGCAGAAGCCATTAAATACTGGAAGGATGTAGACCT
GTATATCGGCGGAGCTGAACATGCTACAGGCCACCTGCTGTACAGTCGTTTCTGGAACAAGTTTTTAAAAGATCTGGGCT
ACGTGCAGGAAGAAGAGCCTTTCAAAAAGCTGATTAACCAGGGTATGATCCAGGGCAGGAGCAACTTTGTATACCGGGTA
ATTGATGAAGAGGGAAGGGGTACAAATAAGCTGGTTTCCTATGGCTTAAGAAAAGATTATAAAACATCGGCATTGCATGT
AGATGTGAATATTGTAGACAATGAGGTCCTGAACATTGAGCAGTTTAAGCTGTTTAGACCCGAATTTGCAGATGCAGAAT
TTATTTTGGAGAATGGCAGATACATCTGTGGTGTTGAAGTAGAGAAGATGTCCAAATCCAAGTTTAACGTGGTAAATCCC
GATGTGCTGATAGAGAGTTACGGTGCTGATACCTTGCGCATGTATGAAATGTTTCTGGGGCCGCTTGAACAGAGCAAACC
ATGGAATACCAATGGCATTGAAGGGGTATTTAAATTCCTGCGTAAGTTTTGGCGCCTGTTCCATAATGAAGCATGGACAT
TTCATGTAAACGATTCGGTGCCCTCTAAAGCGGAACTAAAAGCCCTGCACAAAATCATTAAAAAGGTGCAGGATGATGTT
GAAAGGTTCTCTTTCAATACCTCTGTTTCCAGCTTTATGATTGCAGTGAACGAGCTGACTGATCTGAAATGTAAAAACCG
TCAGGTGCTGGAAGACCTGGTGGTGGTACTTTCACCTTATGCACCACATATATGTGAAGAGCTTTGGATGTTGCTGGGCA
ATGAGGCTGGCAGCTTGTCCTATACACCATATCCAACCTTTAATCCGGCTTACCTGGTTGAAGATGAGTTCAGTTACCCT
GTTTCGGTAAATGGTAAAACCCGTTTAAACCTGAGCATGAGCCTTACTTTAGAGGCTAAAGAAGTAGAAGAAACCGTTTT
GGCCAATGAAGATGTGCAGAAATACCTGGAAGGTAAGGCACCTAAAAAAGTAATTGTAGTGAAGGGCAGGATTGTCAATA
TTGTGATCTAA

Protein sequence :
MDYQFKEIEQKWQKFWAQHKTFKAADASNKPKFYVLDMFPYPSGAGLHVGHPLGYIASDIFSRYKRLKGFNVLHPMGYDS
FGLPAEQYAIQTGQHPALTTEANINTYRKQLDGLGFSFDWSREVRTSDPEYYKWTQWIFMQLFNSWYNLETDRAEDITTL
IEKFNASGSADVKAVCDEDTKTFMPSDWAVMTDEEKQEELLKYRLTYLKESTVNWCAALGTVLANDEVKDGFSERGGHPV
EQKKMMQWSMRISAYAERLLQGLNTIDWPEPVKEMQRNWIGKSIGAAVKFKIEAAVSKALPAGVDAIEVFTTRVDTIFGV
SYLVLAPEHELVTALTTPGQLDAVNSYIAQTKKKSELDRMADTKTVSGAFTGSYVINPVSGERIQLWIADYVLAGYGTGA
VMGVPSGDQRDWLFATHFNLPIVQILDAQQDIEHQADATKDGKYINSGFINGMNYTEATATLNAWLEEQGQGKAKINYRM
RDAIFGRQRYWGEPIPVYFKDGLPYLIKAEELPLLLPEIDKYLPTETGEPPLGRAEDWKYEDEYEYELSTMPGWAGSSWY
WYRYMDAKNDSDFASAEAIKYWKDVDLYIGGAEHATGHLLYSRFWNKFLKDLGYVQEEEPFKKLINQGMIQGRSNFVYRV
IDEEGRGTNKLVSYGLRKDYKTSALHVDVNIVDNEVLNIEQFKLFRPEFADAEFILENGRYICGVEVEKMSKSKFNVVNP
DVLIESYGADTLRMYEMFLGPLEQSKPWNTNGIEGVFKFLRKFWRLFHNEAWTFHVNDSVPSKAELKALHKIIKKVQDDV
ERFSFNTSVSSFMIAVNELTDLKCKNRQVLEDLVVVLSPYAPHICEELWMLLGNEAGSLSYTPYPTFNPAYLVEDEFSYP
VSVNGKTRLNLSMSLTLEAKEVEETVLANEDVQKYLEGKAPKKVIVVKGRIVNIVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-133 44