Gene Information

Name : Phep_2908 (Phep_2908)
Accession : YP_003093168.1
Strain : Pedobacter heparinus DSM 2366
Genome accession: NC_013061
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 3469512 - 3470651 bp
Length : 1140 bp
Strand : -
Note : PFAM: Cys/Met metabolism PLP-dependent enzyme

DNA sequence :
ATGAAGTTCGCGACTAAAGCTATCCACGCGGGTCAGGAGCCTGATCCAACCACAGGGGCCGTAATGACCCCCATATACCA
AACCTCTACGTACTGGCAGAAATCGCCCGGCGATCATAAGGGTTTTGAATATTCCAGAGGTACCAACCCTACGCGTAAAG
CTTTGGAAGATTGCCTGGCGGCCCTGGAAAATGCCAAACATGGCCTGGCTTTCTCGAGCGGAATGGGTGCTACCGATGCA
GTGATGAAATTGCTGCAGCCTGGTGATGAGGTGATCACAGGCAACGATCTTTACGGGGGCTCTTACCGCATCTTTACCAA
GATCTATGCAAAATATGGGATTAAATTCCATTTTCTTGATCTTTCCAGACCGGAAAATATTTTGCCTTTTGTAAACGATA
AAACAAAGCTGGTATGGATAGAGACACCTACCAACCCGACTATGCAGATTGTAGATATCGCCGGTATTTCCAAACTGGCC
AAAGCGCATAACCTGTTGCTGGCGGTTGACAATACTTTTGCTTCCCCTTACCTGCAAAACCCGATAGACCTGGGTGCTGA
TATTGTGATGCACTCAGTTACCAAATACCTGGGCGGCCACTCTGACGTGGTAATGGGTGCTTTAATGGTAAATGACGAAC
AATTGTATAAAGACCTTTGGTTTATTTACAATGCCTGCGGAGCCACTCCTGGTCCGCAAGACGCATTTTTGGTTTTAAGG
GGCATTAAAACCCTGCACCTGCGCATGAAAGCACATTGCGAAAATGGGGCTAAAGTAGCGCATTTCCTTAAAAAACACCC
TAAAGTTGATCGGATCTACTGGCCGGGCTTTGAAGATCATCCGAACCATGCTATTGCCAAACAGCAAATGCGCGATTTTG
GGGGCATGGTATCCTTTACTTTAAAAAATGCCGATCTGCAGGAAACTTTCCGCGTAGCAGGTTCTTTTAAAGTTTTTGCA
CTTGCTGAATCTTTGGGCGGAGTAGAGTCGCTGATCAACCATCCGGTATCTATGACACATGGCTCTATTCCAAAGGAAGA
GCGTGAGAAGGTTGGTGTAACGGATAACCTGTTGCGTTTGAGCGTTGGTATTGAAGATATTGACGATCTTATTCAGGATC
TGGAACAGGCACTTAAATAA

Protein sequence :
MKFATKAIHAGQEPDPTTGAVMTPIYQTSTYWQKSPGDHKGFEYSRGTNPTRKALEDCLAALENAKHGLAFSSGMGATDA
VMKLLQPGDEVITGNDLYGGSYRIFTKIYAKYGIKFHFLDLSRPENILPFVNDKTKLVWIETPTNPTMQIVDIAGISKLA
KAHNLLLAVDNTFASPYLQNPIDLGADIVMHSVTKYLGGHSDVVMGALMVNDEQLYKDLWFIYNACGATPGPQDAFLVLR
GIKTLHLRMKAHCENGAKVAHFLKKHPKVDRIYWPGFEDHPNHAIAKQQMRDFGGMVSFTLKNADLQETFRVAGSFKVFA
LAESLGGVESLINHPVSMTHGSIPKEEREKVGVTDNLLRLSVGIEDIDDLIQDLEQALK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-83 49
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-82 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-58 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Phep_2908 YP_003093168.1 cystathionine gamma-lyase BAC0207 Protein 7e-67 42